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| 1 | Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered显示文摘AIM: To study the blood-brain barrier integrity in prehe-patic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: GroupⅠ: Sham14d, sham operated; GroupⅡ: PH14d, portal vein stenosis; (both groups were used 14 days after surgery); GroupⅢ: Sham40d, Sham operated and GroupⅣ: PH40d Portal vein stenosis (GroupsⅡandⅣused 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility, Hemo-dynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. | Francisco Eizayaga Camila Scorticati Juan P Prestifilippo Salvador Romay Maria A Fernandez José L Castro Abraham Lemberg Juan C Perazzo | 2006 | World Journal of Gastroenterology2006，12，9： | 3 |
| 2 | Business and so- cial reputation: Exploring the concept and main Dimen- sions of corporate reputation 显示文摘 | De Castro G M Lopez J E N Sdez P L | 2006 | Journal of Business Ethics2006，63，4： | 1 |
| 3 | Yield and composition of the essential oil of Ocimum selloi Benlh cultivated under colored netting显示文摘 | Costa L C B Pinto J E B P Castro E M | 2010 | Journal of Essential Oil Research2010，22，1： | 1 |
| 4 | A systems ap- proach for the estimation of the effects of land consolidation project (LCPs): a model and its application 显示文摘 | Castro Colho J Aguiar Pinto P Mira da Silva L | 2001 | Agricultural System2001，68，： | 1 |
| 5 | Anaerobic sludge granulation显示文摘 | Hulshoff P L W de Castro L S I Lettinga G | | 0，，06： | 1 |
| 6 | A systems approach for the estimation of the effects of land consolidation projects (LCPs) :a model and its application 显示文摘 | CASTRO C J AGUIAR P P MIRA D S L | 2001 | Agricultural Systems2001，68，3： | 1 |
| 7 | Correlation between valsalva leak point pressure and maximal urethral closure pressure in women with stress urinary incontinence 显示文摘 | Feldner P C Jr Bezerra L R de Castro R A | 2004 | Int Urogynecol J Pelvic Floor Dysfunct2004，15，3： | 1 |
| 8 | Parameterized fast deeoupled power flow methods for obtaining the maximum loading point of power systems Part Ⅰ and Part Ⅱ显示文摘 | Alves D A Da Silva L C P Castro C A | 2004 | Electric Power Systems Research2004，69，： | 1 |
| 9 | Anaerobic sludge granulation显示文摘 | HULSHOFF P L W CASTRO L S I LETTINGA G | 2004 | Water Research2004，38，： | 1 |
| 10 | Astringency removal of ' Giombo' persimmon fruits submitted to different temperatures 显示文摘 | Antoniolli L R De Camargo e Castro P R Kluge R A | 2002 | Pesquisa Agropecuaria Brasileira2002，37，5： | 1 |
| 11 | Part 3 : Burst tests of pipeline with extensive longitudinal metal loss 显示文摘 | Freire J L F Vieira R D Castro J T P | 2006 | Experimental Techniques2006，30，6： | 1 |
| 12 | Rapid separation of free fatty acids in vegetable oils by capillary electrophoresis 显示文摘 | Castro C Barra P M D C Oliveira M A L D | 2014 | Phytochemical Analysis2014，25，3： | 1 |
| 13 | Reliability evaluation of substation control system显示文摘 | Castro L R Crossley P A | 1999 | IEE Pro-Gener Trans and Distrib1999，146，6： | 1 |
| 14 | Heart energy metabolism and its role in the treatment of heart failure 显示文摘 | Castro P Gabrielli L Verdejo H | 2010 | Rev Med Chil2010，138，8： | 1 |
| 15 | Inhibition of interleukin - lbeta re- duces mouse lung inflammation induced by ex- posure to cigarette smoke 显示文摘 | Castro P Legora - Machado A Cardilo - Reis L | 2004 | Eur J Phar- macol2004，498，123： | 1 |
| 16 | Nanocrystalline chal- copyrite materials (CuInSz and CuInSez ) via low temperature pyroly- sis of molecular single-source preeursors显示文摘 | Castro S L Bailey S G Raffaelle R P | 2003 | Chem Mater2003，15，16： | 1 |
| 17 | Effects of coloured shade netting on the vegetative development and leaf structure of Ocimum sellol显示文摘 | Costa L C D B Pinto J E B P de Castro E M | 2010 | Bragantia2010，69，2： | 1 |
| 18 | Doppler-derived myocardial systolic strain rate is a strong index of left ventricular contractility显示文摘 | GREENBERG N L FIRSTENBERG M S CASTRO P L | 2002 | Circulation2002，105，： | 1 |
| 19 | Constructed wet- land systems vegetated with different plants applied to the treat- ment of tannery wastewater显示文摘 | CALHEIROS C RANGEL A CASTRO P M L | 2007 | Water Research2007，41，： | 1 |
| 20 | Corrosion of reinforced concrete in a topical marine environment and in accelerated tests显示文摘 | Castro P Veleva L Balancan M | 1997 | Construction and Building Materials1997，11，2： | 1 |
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