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| 1 | Finding the solution for incomplete small bowel capsule endoscopy显示文摘AIM:To evaluate whether the use of real time viewer(RTV)and administration of domperidone to patients with delayed gastric passage of the capsule could reduce the rate of incomplete examinations(IE)and improve the diagnostic yield of small bowel capsule endoscopy(SBCE).METHODS:Prospective single center interventional study,from June 2012 to February 2013.Capsule location was systematically checked one hour after ingestion using RTV.If it remained in the stomach,the patient received 10 mg domperidone per os and the location of the capsule was rechecked after 30 min.If the capsule remained in the stomach a second dose of10 mg of domperidone was administered orally.After another 30 min the position was rechecked and if the capsule remained in the stomach,it was passed into the duodenum by upper gastrointestinal(GI)endoscopy.The rate of IE and diagnostic yield of SBCE were compared with those of examinations performed before the use of RTV or domperidone in our Department(control group,January 2009-May 2012).RESULTS:Both groups were similar regarding age,sex,indication,inpatient status and surgical history.The control group included 307 patients,with 48(15.6%)IE.The RTV group included 82 patients,with3(3.7%)IE,P=0.003.In the control group,average gastric time was significantly longer in patients with IE than in patients with complete examination of the small bowel(77 min vs 26 min,P=0.003).In the RTV group,the capsule remained in the stomach one hour after ingestion in 14/82 patients(17.0%)vs 48/307(15.6%)in the control group,P=0.736.Domperidone did not significantly affect small bowel transit time(260min vs 297 min,P=0.229).The capsule detected positive findings in 39%of patients in the control group and 49%in the RTV group(P=0.081).CONCLUSION:The use of RTV and selective administration of domperidone to patients with delayed gastric passage of the capsule significantly reduces incomplete examinations,with no effect on small bowel transit time or diagnostic yield. | José Cotter Francisca Dias de Castro Joana Magalhes Maria Joo Moreira Bruno Rosa | 2013 | World Journal of Gastrointestinal Endoscopy2013,5,12: | 4 |
| 2 | Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease显示文摘This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's disease.The vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of mood.It can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous system.Preclinical and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment responses.These findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's disease.More studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit. | Júlio César Claudino dos Santos Leandro Freitas Oliveira Felipe Micelli Noleto Camilla Teixeira Pinheiro Gusmão Gerly Anne de Castro Brito Glauce Socorro de Barros Viana | 2023 | Neural Regeneration Research2023,18,12: | 2 |
| 3 | 西印度洋地区海草生态系统显示文摘海草是海洋被子植物,广泛分布在温带和热带的海岸带水域,是地球上水生生态系统中最具生产力的生物之一。在西印度洋地区大概有13种海草,这些海草覆盖了12000kg海岸线的近岸柔软海底广大区域。海草床一般分布在潮间带和潮下带,有时向下延伸至40m,并经常出现在珊瑚礁和红树林附近。由于具有很高的初级生产力和复杂的栖息环境,海草供养了许多底栖生物和浮游生物。许多鱼类和贝类,包括那些具有商业价值的种类都被吸引到海草栖息地,将海草作为其食物来源和避难场所,特别是在它们的幼年期。分布在西印度洋海草床附近广泛而丰富的鱼类资源就足以说明这一点。这些鱼分别属于天竺鲷科、亚科、玻甲鱼科、银鲈科、虾虎鱼科、隆头鱼科、裸颊鲷科、笛鲷科、单角亚科、鹦嘴鱼科、科、篮子鱼科、海龙科和Teraponidae科。因此,西印度洋地区的海草生态系统无论对当地还是整个地区的渔业发展都是非常有价值的资源。尽管如此,与其他地区相比,该地区有关海草资源的研究还十分缺乏,而且大多数研究也都集中在植物多样性和生态学上。本文主要阐述西印度洋地区海草床研究现状,特别强调鱼类和渔业。目前,该课题的大多数研究主要是在东非海岸开展的,如肯尼亚,坦桑尼亚,莫桑比克以及南非东部地区,而在索马里和西印度洋地区的岛屿国家(塞舌尔、科摩罗、法属留尼旺岛、毛里求斯、马达加斯加等)此类研究却很少,有关海草鱼类生态系统的论文也少有发表,而且大部分都是描述性的。因此,需要通过研究和实验获得有关描述模式和处理方法的科学知识。关于海草鱼类群落的定量研究,类似本文所介绍的案例研究在西印度洋地区是很少的,而这些研究对于渔业的管理前景而言是必不可少的。值得强调的是由于海岸人口的不断增长以及人类活动的侵扰给该地区海草床带来的压力与日俱增,如污染,海水富营养化,沉积作用,捕鱼以及无脊椎动物的采集等活动,而这些活动对于海草床的影响却鲜为人知。因此,需要开展广泛的研究,为西印度洋地区海草生态系统可持续管理提供有用的信息服务。 | Martin Gullstrm Maricela de la Torre Castro Salomo O.Bandeira Mats Bjrk Mattis Dahlberg Nils Kautsky Patrik Rnnbck Marcus C.hman 章任群 | 2002 | AMBIO-人类环境杂志2002,31,7: | 2 |
| 4 | Singular and non-singular approaches for predicting fatigue crack growth be- havior显示文摘 | Castro J T P Meggiolaro M A Miranda A C O | 2005 | International Journal of Fatigue2005,27,: | 1 |
| 5 | A novel muta-tion in the growth and differentiation factor 9 (GDF9)gene is associated, in homozygosis, with increased ovula-tion rate in Santa Ines sheep 显示文摘 | Melo E O Silva B D M Castro E A | 2008 | Biology of Reproduction2008,78,141: | 1 |
| 6 | Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins显示文摘 | Sangfelt O Erickson S Castro J | 1999 | Oncogene1999,18,18: | 1 |
| 7 | Pneumococcal antimicro-bial resistance:therapeutic strategy and management in community-acquired pneumonia显示文摘 | Aspa J Rajas O de Castro F R | 2008 | Expert Opin Pharmacother2008,9,2: | 1 |
| 8 | Fuzzy granular gravitational clustering algorithm for multivariate data显示文摘 | SANCHEZ M A CASTILLO O CASTRO J R | 2014 | Information Sci- ences2014,279,2: | 1 |
| 9 | Interpretation of chloride profiles from concrete exposed to tropical marine environments显示文摘 | CASTRO P DE RINCON O T PAZINI E J | 2001 | Cement and Concrete Research2001,31,4: | 1 |
| 10 | Concurrent and Simple Digital Controller of an AC/DC Converter with Power Factor Correction Based on an FPGA显示文摘 | De Castro A Zumel P Garcia O | 2003 | IEEE Trans on Power Electronics2003,18,1: | 1 |
| 11 | Exhalednitrie oxide predicts control in patients with difllcult-to-treat asthma显示文摘 | Perez-de-LIano LA Carballada F Castro Anon O | 2010 | Eur Respir J2010,35,6: | 1 |
| 12 | Advanced oxidation processes for treatment of effluents from a detergent industry显示文摘 | RuiC. Martins AdriánM.T. Silva Sérgio Castro‐Silva Paulo Gar??o‐Nunes RosaM. Quinta‐Ferreira | 2011 | Environmental Technology2011,,9: | 1 |
| 13 | Glandular trichornes on the leaves and flowers of Plectranthus ornatus morphology,distribution and histochemistry显示文摘 | ASCENS(A)O L MOAT L CASTRO M M | 1999 | Annals of Botany1999,84,: | 1 |
| 14 | Histologic characterization of acute spinal cord injury treated with intravenous methylprednisolone显示文摘 | Mecrola A O'Brien MF Castro BA | 2002 | J Orthop Trauma2002,16,3: | 1 |
| 15 | COL1A1 Sp1-binding site polymorphism as a risk factor for genital prolapse显示文摘 | Andrea Moura Rodrigues Manoel Jo?o Batista Castello Gir?o Ismael Dale Cotrim Guerreiro Silva Marair Gracio Ferreira Sartori Karina de Falco Martins Rodrigo de Aquino Castro | 2008 | International Urogynecology Journal2008,,11: | 1 |
| 16 | Total volatile base nitrogen and its use to assess freshness in European sea bass stored in iee显示文摘 | Castro P Padr O N J C P | 2006 | Food Control2006,,17: | 1 |
| 17 | Histologic characterization of acute spinal cord injury treated with intravenous methylpred- nisolone显示文摘 | Merola A O'Brien MF Castro BA | 2002 | J Orthop Trauma2002,16,: | 1 |
| 18 | Oral health - relatedquality of life of 11 and 12year old public school children in Rio de Janeiro 显示文摘 | Castro Rde A Portela MC Le o AT | 2011 | Community Dent Oral Epidemiol2011,39,4: | 1 |
| 19 | Drug-resistant pneumococcal pneumonia:clinical relevance and related factors显示文摘 | Aspa J Rajas O Rodriguez de Castro F | 2004 | Clin Infec DiS2004,38,: | 1 |
| 20 | Corrison behavior of Zn and Zn alloy coatings in alkaline media显示文摘 | Girciene O Ramanauskas R Castro P | 2001 | Trans I M F2001,79,6: | 1 |