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| 1 | Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases显示文摘AIM:To access the efficacy of chemotherapy plus radiofrequency ablation(RFA)as one line of treatment in inoperable colorectal liver metastases.METHODS:Eligible patients were included in three PhaseⅡstudies.In the first study percutaneous RFA was used first followed by 6 cycles of 5-fluorouracil,leucovorin and irinotecan combination(FOLFIRI)(adjunctive chemotherapy trial).In the other two,chemotherapy(FOLFIRI or 5-fluorouracil,leucovorin and oxaliplatin combination)up to 12 cycles was used first with percutaneous RFA offered to responding patients (primary chemotherapy trials).RESULTS:Thirteen patients were included in the adjunctive chemotherapy trial and 17 in the other two.At inclusion they had 1-4 liver metastases(up to 6.5 cm in size).Two patients died during chemotherapy.All patients in the adjunctive chemotherapy trial and 44%in the primary chemotherapy studies had their metastases ablated.Median PFS and overall survival in the adjunctive study were 13 and 24 mo respectively while in the primary chemotherapy studies they were 10 and 21 mo respectively.Eighty one percent of the patients had tumour relapse in at least one previously ablated lesion.CONCLUSION:Chemotherapy plus RFA in patients with low volume inoperable colorectal liver metastases seems safe and relatively effective.The high local recurrence rate is of concern. | Joseph Sgouros James Cast Krishna K Garadi Maria Belechri David J Breen John RT Monson Anthony Maraveyas | 2011 | World Journal of Gastrointestinal Oncology2011，3，4： | 4 |
| 2 | Nleumaeic dilatation in effective long - term treatment for achalasia 显示文摘 | Kak PO Gilben J CastelI DO | 2011 | Digest Dis Sci2011，43，9： | 1 |
| 3 | Essential fatty acid requirement of the Chinese prawn, Penaeus chinensis 显示文摘 | XU X WEN J J CASTE L L | 1994 | Aquaculture1994，127，1： | 1 |
| 4 | Recombinant human interleukin-6 (IL-6/ BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes 显示文摘 | Casted JV Gomez-Lechon M J David M Hirano T Kishimoto T Heinrich PC | 1988 | FEBS Lett1988，232，2： | 1 |
| 5 | Immune response in healthy volunteers vaccinated with killed leishmanial promastigotes plus BCG I skin test reactivity T cell proliferation and interferon-gamma production显示文摘 | Blackwell J Trujillo D | 1994 | Vaccine1994，12，： | 1 |
| 6 | Pitfalls of liver stiffness measurement:a 5-year prospective study of 13,369 examinations显示文摘 | Castéra L Foucher J Bernard PH | | 0，，03： | 1 |
| 7 | The effectiveness of disaster training for health care workers: a systematic review显示文摘 | Williams J Noeera M Casted C | 2008 | Ann Emerg Med2008，52，3： | 1 |
| 8 | A theory of self-esteem 显示文摘 | Cast Alicia D Burke Peter J | 2002 | So- cial Forces2002，80，10： | 1 |
| 9 | Prospective com parison of transient elastography,Fibrotest,APRI,and liver biopsy for the assessm ent of fibrosis in chronic hepatitis C显示文摘 | Castéra L VerqniolJ Foucher J | 2005 | Gastroenterology2005，128，2： | 1 |
| 10 | Encapsulation of bovino serum albumin in poly(lactide co -glycolide) microsphcrcs by the solid in oil in water technique 显示文摘 | Cast~llanos I J Carrasquillo K G Lopez J D | 2001 | J Pharm Pharmacol2001，53，2： | 1 |
| 11 | Prevalence and factors associated with failure of liver stiffness measurement using Fibro- Scan in a prospective study of 2114 examinations显示文摘 | Foucher J Castéra L Bernard PH | 2006 | Eur J Gas- troenterol Hepatol2006，18，4： | 1 |
| 12 | 查看详情显示文摘 | Saint Cast P Benick J Kania D Weiss L Hofmann M Rentsch J Preu R Glunz W G | | 0，，： | 1 |
| 13 | Appalachina basin stratigraphic response to convergent-margin structural evolution显示文摘 | Caste J W | 2001 | Basin Research2001，13，4： | 1 |
| 14 | Percutaneous transhepatic biliary drainage (PTBD) with or without stenting-complications,re stent rate and a new risk stratification score显示文摘 | Tapping CR Byass OR Cast J | 2011 | Eur Radiol2011，21，： | 1 |
| 15 | VP1,the putative RNA-dependent RNA polymerase of infectious bursal disease virus,forms complexes with the capsid protein VP3,leading to efficient encapsidation into virus-like particles显示文摘 | Lombardo E Maraver A Castón J R | 1999 | J Virol1999，73，8： | 1 |
| 16 | HPLC Determination of tetracyclines in lamb musele using an RP-C18 monolithic显示文摘 | CASTE UARI M GARCIA REGUEIRO J A | 2003 | Type Column Chromatographia2003，58，11： | 1 |
| 17 | Early experience with percutaneous radiofrequency ablation of small solid renal masses 显示文摘 | Choudhry S H Cast J E Cooksey G | 2003 | AJR2003，180，12： | 1 |
| 18 | Pitfalls of liver stiffness measurement:a 5-vear prospective study of 13,369examinations显示文摘 | Castéra L Foucher J Bernard P H | | 0，，03： | 1 |
| 19 | Allelo- chemicals in soil from no-tillage versus conventional-tillage wheat ( Triticum aestivum ) fields 显示文摘 | CAST K G MCPHERSON J K POLLARD A J | 1990 | Journal of Chemical E cology1990，16，7： | 1 |
| 20 | Epidemiology of invasive fungal infection显示文摘 | Castón-Osorio J J Rivero A Torre-Cisneros J | 2008 | Int J Antimicrob Agents2008，32，2： | 1 |
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