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| 1 | Actual concept of 'probiotics':Is it more functional to science or business?显示文摘It is our contention that the concept of a probiotic as a living bacterium providing unspecified health benefits is inhibiting the development and establishment of an evidence base for the growing field of pharmacobiotics.We believe this is due in part to the current regulatory framework,lack of a clear definition of a probiotic,the ease with which currently defined probiotics can be positioned in the market place,and the enormous profits earned for minimum investment in research.To avoid this,we believe the following two actions are mandatory:international guidelines by a forum of stakeholders made available to scientists and clinicians,patient organizations,and governments;public research funds made available to the scientific community for performing independent rigorous studies both at the preclinical and clinical levels. | Michele Caselli Francesca Cassol Girolamo Calò John Holton Giovanni Zuliani Antonio Gasbarrini | 2013 | World Journal of Gastroenterology2013，19，10： | 3 |
| 2 | Modern surgical strategies for perianal Crohn's disease显示文摘One of the most challenging phenotypes of Crohn’s disease is perianal fistulizing disease(PFCD).It occurs in up to 50%of the patients who also have symptoms in other parts of the gastrointestinal tract,and in 5%of the cases it occurs as the first manifestation.It is associated with severe symptoms,such as pain,fecal incontinence,and a significant reduction in quality of life.The presence of perianal disease in conjunction with Crohn’s disease portends a significantly worse disease course.These patients require close monitoring to identify those at risk of worsening disease,suboptimal biological drug levels,and signs of developing neoplasm.The last 2 decades have seen significant advancements in the management of PFCD.More recently,newer biologics,cell-based therapies,and novel surgical techniques have been introduced in the hope of improved outcomes.However,in refractory cases,many patients face the decision of having a stoma made and/or a proctectomy performed.In this review,we describe modern surgical management and the most recent advances in the management of complex PFCD,which will likely impact clinical practice. | Gilmara Pandolfo Zabot Ornella Cassol Rogerio Saad-Hossne Willem Bemelman | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 3 | Follicular epithelial dysplasi- a of the thyroid: morphological and immunohistochemical charac- terization of a putative preneoplastic lesion to papillary thyroid car- cinoma in chronic lymphocytic thyroiditis 显示文摘 | Chui MH Cassol CA Asa SL | 2013 | Virchows Arch2013，462，5： | 1 |
| 4 | Persistent microbial translocation and immune activation in HIV-l-infected South Africans receiving combination antiretroviral therapy显示文摘 | Cassol E Malfeld S Mahasha P | 2010 | J Infect Dis2010，202，5： | 1 |
| 5 | Macrophage polarization in health and disease 显示文摘 | Cassetta L Cassol E Poli G | 2011 | Scientific World Journal2011，11，： | 1 |
| 6 | Dendritic cell-specific ICAM-3 gabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro 显示文摘 | Cassol E Cassetta L Rizzi C | 2013 | AIDS2013，27，5： | 1 |
| 7 | Detection of HIV type 1 env subtypes, A, B, C and E in Asia using dried blood spots:a new surveillance tool for molecular epidemiology显示文摘 | Cassol S Weniger BG Babu PG | 1996 | AIDS Res Hum Retroviruses1996，12，： | 1 |
| 8 | Physiological analysis of leaf senescence of two rice cul- tivars with different yield potential显示文摘 | Falqueto A R Cassol D Magalhes Junior A M ez at | 2009 | J Pesq Agropec Bras2009，44，7： | 1 |
| 9 | Follicular epithelial dysplasia of the thyroid: morphological and immunohistochemical characterization of a putative preneoplastic lesion to papillary thyroid carcinoma in chronic lymphocytic thyroiditis显示文摘 | Chui M H Cassol C A Asa S L | 2013 | Virchows Arch2013，462，5： | 1 |
| 10 | Prognostic and predictive markers in medullary thyroid carcinoma显示文摘 | Erovic B M Kim D Cassol C | | Endocr Pathol0，23，4： | 1 |
| 11 | Macrophage polarization in health and disease 显示文摘 | Cassetta L Cassol E Poll G | 2011 | Scientific World Journal2011，11，： | 1 |
| 12 | M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms显示文摘 | Cassol E Cassetta L Rizzi C | 2009 | J Immunol2009，182，10： | 1 |
| 13 | The role of Pd nanoparticles in ionic liquid in the Heck reaction显示文摘 | CASSOL C C UMPIERRE A P MACHADO G | 2005 | J Am Chem Soc2005，127，10： | 1 |
| 14 | The Effects of Creatine Supplementation arid Physical Exercise on Traumatic Brain Injury显示文摘 | Preire Royes LF Cassol G | 2015 | Mini Rev Med Chem2015，16，1： | 1 |
| 15 | Macrophage polarization in health and disease 显示文摘 | Cassetta L Cassol E Poli G | 2011 | Scientific World Journal2011，11，2： | 1 |
| 16 | Prevalence of symptoms of asthma,rhinitis,and atopic eczema among adolescents living in urban and rural areas in different regions of Brazil显示文摘 | Solé D Cassol VE Silva AR | | 0，，06： | 1 |
| 17 | Engineered polyamine accumulation in tomato enhances phytonutrient content,juice quality,and vine life显示文摘 | Mehta R A Cassol T Li N | 2002 | Nature Biotechnology2002，20，6： | 1 |
| 18 | Effects of age on pulmonary artery systolic pressure at rest and during exercise in normal adults 显示文摘 | Mahjoub H Levy F Cassol M | 2009 | EurJ Echocardiogr2009，10，5： | 1 |
| 19 | Flow hydraulics and sediment transport in rills of a sandy clay loam soil显示文摘 | Cantalice J R B Cassol E A Reichert J M | 2005 | Revista Brasileira De Ciencia Do Solo2005，29，4： | 1 |
| 20 | Prognostic and predictive markers in medullary thyroid carcinoma显示文摘 | Erovic B M Kim D Cassol C | 2012 | Endocr Pathol2012，23，4： | 1 |
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