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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Modeling and control of magnetorheological dampers forseismic response reduction 显示文摘 | DYKE S J SPENCER B F SAIN M K CARLSON J D | 1996 | Smart Materials and Structures1996，5，5： | 2 |
| 3 | Sentinel lymph node biopsy for breast cancer: a suitable alternative to routine axillary dissection in multi-inatitutional practice when optimal technique is used显示文摘 | MCMASTERS K M TUTTLE T M CARLSON D J | 2000 | J Clin Oncel2000，18，13： | 1 |
| 4 | Floc morphology and cyclic sheafing recovery: comparison of alum and polyaluminum chloride coagulants 显示文摘 | McCurdy K Carlson K Gregory D | 2004 | Water Research2004，38，2： | 1 |
| 5 | RH-5849, a nonsteroidal ecdysone agonist: effects on larval lepidoptera 显示文摘 | K D Wing R A Slawecki G R Carlson | 1988 | Science1988，241，： | 1 |
| 6 | Development of new feeding-distance rules using casting simulation: part II, the new rules 显示文摘 | Ou S Carlson K D Hardin R A | 2002 | Metallurgical and Materials Transactions B2002，33，： | 1 |
| 7 | Viscoelastic properties of magneto-and electro-rheological fluids显示文摘 | CARLSON J D NIXON D A | 1994 | Journal of Intelligent Material Systems and Structure1994，，5： | 1 |
| 8 | Construction and initial validation of a multidimensional measure of work - family conflict 显示文摘 | Carlson D S Kacmar K M Williams L J | 2000 | Journal of Vocational Behavior2000，56，2： | 1 |
| 9 | Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1Subtype B Gag Proteins显示文摘 | Boutwell C L Carlson J M Lin T H Seese A Power K A Peng J Tang Y Brumme Z L Heckerman D Schneidewind A Allen TM | 2013 | J Virol2013，87，7： | 1 |
| 10 | 显示文摘 | Carlson J D Weiss K D | 1994 | Machine Design1994，，8： | 1 |
| 11 | Acid- and basecatalyzed hydrolysis of chloroacetamide herbicides 显示文摘 | Carlson D L Than K D Roberts A L | 2006 | Journal of Agricultural and Food Chemistry2006，53，16： | 1 |
| 12 | A Growing Attraction to Magnetic Fluids 显示文摘 | Carlson J D Weiss K D | 1994 | Machine Design1994，8，1： | 1 |
| 13 | Prediction of shrinkage pore volume fraction using a dimensionless niyama criterion 显示文摘 | Carlson K D Beckermann C | 2009 | Metallurgical and Materials Transactions A2009，40，： | 1 |
| 14 | Engineering applications of electro-rheological materials显示文摘 | Weiss K D Carlson J D | 1993 | Journal of Intelligent Material System and Structure1993，10，： | 1 |
| 15 | Ubiquitous tar balls with a California-source signature on the shorelines of Prince William Sound, Alaska显示文摘 | Kvenvolden K A Hostettler F D Carlson P R Rapp J B Threlkeld C N Warden A | 1995 | Environ Sci Technol1995，29，10： | 1 |
| 16 | Phenomenological model of a magnetorheological damper 显示文摘 | Spencer B F Dyke S J Sain M K Carlson J D | 1997 | Journal of Engineering Mechanics1997，123，3： | 1 |
| 17 | Construction and initial validation of a multidimensional measure of work-family conflict显示文摘 | Carlson S D Kaoman K M Willianus Ld | 2000 | dournal of Vacational Behavior2000，，9： | 1 |
| 18 | Regulatory Focus as a Mediator of the Influ- ence of Initiating Structure and Servant Leadership on Employee Behavior显示文摘 | NEUBERT M J KACMAR K M CARLSON D S | 2008 | Journal of Applied Psy- chology2008，93，6： | 1 |
| 19 | A processbased hydrology submodel dynamically linked to plant component of the simulation of production and utilization on rangelands SPUR model显示文摘 | Pierson F B Carlson D H Spaeth K E | 2001 | Ecological Modeling2001，141，： | 1 |
| 20 | Impacts of maternal selenium and nutritional level on growth, adiposity, and glucose tolerance in female offspring in sheep 显示文摘 | Vonnahme K A Luther J S Reynolds L P Hammer C J Carlson D B Redmer D A Caton J S | 2010 | Domestic Animal Endocrinology2010，39，4： | 1 |
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