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| 1 | Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis显示文摘瞄准:在有人半胱氨酸(HCY ) 和 haemostatic 系统的各种各样的部件的 PBC 和它的关系估计 hypercoagulability。方法:我们调查了 51 个 PBC 病人(43F/8M;意味着年龄:63+/-13.9 年) 并且 102 个健康题目(86 个 women/16 人;63+/-13 年) ,并且由 PFA-100 由 Sonoclot 分析和血小板功能在全血评估了 haemostatic 过程设备。我们然后测量了 HCY (禁食并且在蛋氨酸装载以后) ,织物因素(TF ) , thrombin-antithrombin 建筑群(梭织) , D 暗淡(D-D ) , thrombomodulin (TM ) , folic,维生素 B6 和 B12 血浆铺平。C677T 5,10-methylenetetrahydrofolate 还原酶(MTHFR ) 多型性被分析。结果:病人的 Sonoclot 率值是显著地(P<0.001 ) 比那些高控制。山峰价值的 Sonoclot 时间和 PFA-100 闭合时间在病人和控制是可比较的。梭织, TF 和 HCY 层次,两个在禁食并且蛋氨酸以后的装载,显著地(P<0.001 ) 在病人更高与比在控制。维生素缺乏在 45/51 病人(88.2%) 被检测。同型结合的 TT677 MTHFR 遗传型的流行比在控制(17.5%)(P<0.05 ) 在病人(31.4%) 是显著地更高的。Sonoclot 率价值与 HCY 层次和 TF 显著地相关。结论:在 PBC, hyper-HCY 与维生素缺少和基因预先安排因素有关。内皮激活的增加的 TF 和 HCY 层次和符号与 hypercoagulability 被联系并且可以在血凝固激活有一个重要角色。 | Maria Rosa Biagini Alessandro Tozzi Rossella Marcucci Rita Paniccia Sandra Fedi Stefano Milani Andrea Galli Elisabetta Ceni Marco Capanni Raffaele Manta Rosanna Abbate Calogero Surrenti | 2006 | World Journal of Gastroenterology2006，12，10： | 6 |
| 2 | Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants显示文摘 | Ruggeri L Capanni M Urbani E | 2002 | Science2002，295，6： | 2 |
| 3 | Role of natural killer cell alloreactivity in HLA - mismatched hematopoietic stem- cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，1： | 2 |
| 4 | Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants显示文摘 | Ruggeri L Capanni M Urbani E | 2002 | Science2002，295，5562： | 1 |
| 5 | Cellular therapy: exploiting NK cell alloreactivity in transplantation显示文摘 | Ruggeri L Capanni M Martelli MF | 2001 | Curt Opin Hematol2001，8，6： | 1 |
| 6 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，1： | 1 |
| 7 | Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia:challenging its predictive value显示文摘 | Ruggeri L Mancusi A Capanni M | 2007 | Blood2007，110，1： | 1 |
| 8 | Altered pre lamin A processing is a common mechanism leading to lipodystrophy显示文摘 | Capanni C Mattioli E Columbaro M | 2005 | Hum Mol Genet2005，14，： | 1 |
| 9 | Phase-shifting speckle interfereo-metry: a noise reduction filter for phase un- wrapping 显示文摘 | CAPANNI A PEZZATI L BERTANI D | 1997 | Optical Engineering1997，36，9： | 1 |
| 10 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，： | 1 |
| 11 | Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants显示文摘 | Ruggefi L Capanni M Urbani E | 2002 | Science2002，295，5562： | 1 |
| 12 | Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study显示文摘 | CAPANNI M CALELLA F BIAGINI M R | 2006 | Alimentary Pharmacology and Therapeutics2006，23，8： | 1 |
| 13 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，1： | 1 |
| 14 | Investigation of the effects of copper ions on protein aggregation using a model system显示文摘 | Capanni C | 2004 | Cell Mol Life Sci2004，61，78： | 1 |
| 15 | Effectiveness of donor natural killer cell alloreaetivity in mismatched hematopoietic transplants 显示文摘 | Ruggeri I Capanni M Urbani E | 2002 | Sience2002，295，5562： | 1 |
| 16 | Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic trans- plantation for acute myeloid leukemia:challenging its predictive val- ue显示文摘 | Rugged L Mancusi A Capanni M | 2007 | Blood2007，110，1： | 1 |
| 17 | Exploitation of alloreactive NK cells in adoptive immunotherapy of cancer显示文摘 | Ruggeri L Mancusi A Capanni M | 2005 | Curt Opin Immunol2005，17，： | 1 |
| 18 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | RUGGERI L CAPANNI M CASUCCI M | 1999 | Blood1999，94，1： | 1 |
| 19 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，1： | 1 |
| 20 | Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation显示文摘 | Ruggeri L Capanni M Casucci M | 1999 | Blood1999，94，： | 1 |
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