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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Isolation and characterization of a zinc finger polypede gene at the human chromosome 11 Wilms'tumor locus显示文摘 | Call KM Glaser T Ito CY | | Cell0，60，： | 1 |
| 3 | Silver toxicity to #Chironomus# tentans in two freshwater sediments显示文摘 | CALL D J POLKINGHORNE C N MARKEE T P | 1999 | Environmental Toxicological Chemistry1999，18，1： | 1 |
| 4 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call K M Glaser T Ito C Y | 1990 | Ce111990，60，3： | 1 |
| 5 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call KM Glaser T Ito CY | 1990 | Cell1990，60，3： | 1 |
| 6 | Isolation and characterization of zine finger polypeptide gene at the human chromosome 11 wilms' tumor locus 显示文摘 | Call K M Glaser T Ito C Y | 1990 | Cell1990，，60： | 1 |
| 7 | Removal of naphthalene,phenanthrene,and pyrene by sorbents from hot gas显示文摘 | MASTRAL A M GARCIAA T CALLEN M S | 2001 | Environ Sci Technol2001，35，： | 1 |
| 8 | Three-ring PAH removal from waste hot gas by sorbents:influence of the sorbent characteristics显示文摘 | MASTRAL A M GARCIAA T CALLEN M S | 2002 | Environ Sci Technol2002，36，： | 1 |
| 9 | Isolation and characterization of a zinc fmger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call KNI Glaser T Ito CY | 1990 | Cell1990，60，3： | 1 |
| 10 | Does the determination of inorganic arsenic in rice depend on the method 显示文摘 | de la Calle M B Emteborg H Linsinger T P J | 2011 | Trends in Ana- lytical Chemistry2011，30，： | 1 |
| 11 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call KM Glaster T Ito CY | 1990 | Cell1990，60，： | 1 |
| 12 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms tumor loeus显示文摘 | Call K M Glaser T Ito C Y | 1990 | Ce111990，60，3： | 1 |
| 13 | Perception and transduction of an elicitor signal in cultured Parsley cells 显示文摘 | Numberger T Calling C Hahlbrock K | 1994 | Biochemical Society Symposium1994，60，： | 1 |
| 14 | Analytical methods for the determination of acrylamide in the food products:a review显示文摘 | Beatriz de la Calle M Anklam E | 2003 | Food Additives and Contaminants2003，20，10： | 1 |
| 15 | Carbohydrate restfietion, as a first-Line dietary inter-ention, effeetively reduees biomarkers of metabolie syndromein emiratiAduhs 显示文摘 | Sarraj T Saadi H Calle MC | 2009 | Nutr2009，，7： | 1 |
| 16 | Improved screening coefficients for the hydrogenic ion model显示文摘 | Marchand R Calle S and Lee Y T | 1990 | JQRST1990，43，2： | 1 |
| 17 | Herpesvirus - associated papillomas in koi carp ( Cyprinus carpio) 显示文摘 | CALLE P R MCNAMARA T KRESS Y | 1999 | J Zoo Wildl Med1999，30，1： | 1 |
| 18 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus 显示文摘 | Call KM Glaser T Ito CY | 1990 | Cell1990，60，3： | 1 |
| 19 | A field investigation of the relationship between zinc and acid volatile sulfide concentrations in freshwater sediments 显示文摘 | Ankley G T Liber K Call D J | 1996 | Journal of Aquatic Ecosystem Health1996，5，4： | 1 |
| 20 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call KM Glaser T Ito CY | 1990 | Cell1990，600，： | 1 |
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