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| 1 | Clinical significance of main pancreatic duct dilation on computed tomography: Single and double duct dilation显示文摘AIM: To study the patients with main pancreatic duct dilation on computed tomography (CT) and thereby to provide the predictive criteria to identify patients at high risk of significant diseases, such as pancreatic cancer, and to avoid unnecessary work up for patients at low risk of such diseases. METHODS: Patients with dilation of the main pancreatic duct on CT at Emory University Hospital in 2002 were identified by computer search. Clinical course and ultimate diagnosis were obtained in all the identified patients by abstraction of their computer database records. RESULTS: Seventy-seven patients were identified in this study. Chronic pancreatitis and pancreatic cancer were the most common causes of the main pancreatic duct dilation on CT. Although the majority of patients with isolated dilation of the main pancreatic duct (single duct dilation) had chronic pancreatitis, one-third of patients with single duct dilation but without chronic pancreatitis had pancreatic malignancies, whereas most of patients with concomitant biliary duct dilation (double duct dilation) had pancreatic cancer. CONCLUSION: Patients with pancreatic double duct dilation need extensive work up and careful followup since a majority of these patients are ultimately diagnosed with pancreatic cancer. Patients with single duct dilation, especially such patients without any evidence of chronic pancreatitis, also need careful follow-up since the possibility of pancreatic malignancy, including adenocarcinoma and intraductal papillary mucinous tumors, is still high. | Mark D Edge Maarouf Hoteit Amil P Patel Xiaoping Wang Deborah A Baumgarten Qiang Cai | 2007 | World Journal of Gastroenterology2007，13，11： | 9 |
| 2 | Elucidation of the ‘Honeycrisp’ pedigree through haplotype analysis with a multi-family integrated SNP linkage map and a large apple (Malus×domestica) pedigree-connected SNP data set显示文摘The apple(Malus×domestica)cultivar Honeycrisp has become important economically and as a breeding parent.An earlier study with SSR markers indicated the original recorded pedigree of‘Honeycrisp’was incorrect and‘Keepsake’was identified as one putative parent,the other being unknown.The objective of this study was to verify‘Keepsake’as a parent and identify and genetically describe the unknown parent and its grandparents.A multi-family based dense and high-quality integrated SNP map was created using the apple 8 K Illumina Infinium SNP array.This map was used alongside a large pedigree-connected data set from the RosBREED project to build extended SNP haplotypes and to identify pedigree relationships.‘Keepsake’was verified as one parent of‘Honeycrisp’and‘Duchess of Oldenburg’and‘Golden Delicious’were identified as grandparents through the unknown parent.Following this finding,siblings of‘Honeycrisp’were identified using the SNP data.Breeding records from several of these siblings suggested that the previously unreported parent is a University of Minnesota selection,MN1627.This selection is no longer available,but now is genetically described through imputed SNP haplotypes.We also present the mosaic grandparental composition of‘Honeycrisp’for each of its 17 chromosome pairs.This new pedigree and genetic information will be useful in future pedigree-based genetic studies to connect‘Honeycrisp’with other cultivars used widely in apple breeding programs.The created SNP linkage map will benefit future research using the data from the Illumina apple 8 and 20 K and Affymetrix 480 K SNP arrays. | Nicholas P Howard Eric van de Weg David S Bedford Cameron P Peace Stijn Vanderzande Matthew D Clark Soon Li Teh Lichun Cai James J Luby | 2017 | Horticulture Research2017，4，1： | 9 |
| 3 | Protein phosphatase PP4 is overexpressed in human breast and lung tumors显示文摘 | Bo Wang Ailian Zhao Lingling Sun Xueyan Zhong Jianing Zhong Haibo Wang Minhua Cai Jing Li Yi Xu Ji Liao Jianli Sang Dipanj an Chowdhury Gerd P Pfeifer Yun Yen Xingzhi Xu | 2008 | Cell Research2008，18，9： | 2 |
| 4 | Spatial pattern and its evolution of Chinese provincial population: Methods and empirical study显示文摘中国一直在经历一个崭新的都市化过程。在 2011,瓷器城市的人口与 51.27% 的都市化率到达了 6.91 亿。都市化水平被期望在 2030 在中国增加到 70% ,反映将近 3 亿个人将从农村区域移植到在这个时期上的城市的区域的设计。同时,瓷器人口的全部的富饶率由于经济生长,环境带能力,和现代社会知觉的联合效果正在衰退。中国政府由允许生育夫妇只要他们的任何一个来自一个一个孩子家庭,有第二个孩子逐渐地松开了它的一个孩子政策。在如此的很快发展中的国家,自然生长和空间移植将一致地重塑人口的空间模式。未来的精确预言人口和它的进化趋势的空间模式是批评的给政策制定的过程并且包括都市化,陆地使用发展,生态的保存和环境保护的在中国的空间计划调音。在这份报纸,一个自顶向下的方法被开发从 2010 ~ 2050 在省的水平和省的迁居与两自然人口生长的考虑投射瓷器未来人口的空间分发。这上的大楼,空间模式和中国省的人口的进化趋势被分析。结果建议中国人口的全面空间模式将是不大可能的在下四十年变化了,与有最高的人口密度的东方区域并且由中央区域,东北和西方区域列在后面。在东方,上海,北京,天津和江苏的四个省,将以人口密度仍然是顶在中国,和 Xinjiang, Qinghai 和西藏将继续有人口的最低密度。我们介绍了一个索引系统以省的人口密度分类中国省进三个范畴:快变化的占据区域(FCPR ) ,低变化占据区域(LCPR ) 和不活跃的占据区域(IPR ) 。在 FCPR,瓷器人口被投射继续在网移民集中收到将近 99% 新积累的流动人口的领先的类型(NILT ) 区域。上海的人口密度,北京,浙江将在 2030 达到顶点,当在广东的人口密度将不停地增加直到 2035 时。为 75% 移民人口让移民赚领先的类型(NELT ) 区域愿望报道,包括河南省,安徽,重庆和湖北。自然生长将在带类型区域的自然生长起一个主导的作用,例如辽宁和山东,因为将有很少移民人口。由于大量动人外面劳动和逐渐地衰退的富饶率, LCPR 区域的人口密度展出一向下趋势,除了福建和海南。西方的省的多数将是可能的仍然是相对低的人口密度,与平均价值仅仅 100 个人每 km 2 。 | DENG Yu LIU Shenghe CAI Jianming LU Xi Chris P NIELSEN | 2015 | Journal of Geographical Sciences2015，25，12： | 2 |
| 5 | Doped graphene/carbon black hybrid catalyst giving enhanced oxygen reduction reaction activity with high resistance to corrosion in proton exchange membrane fuel cells显示文摘Nitrogen doping of the carbon is an important method to improve the performance and durability of catalysts for proton exchange membrane fuel cells by platinum–nitrogen and carbon–nitrogen bonds. This study shows that p-phenyl groups and graphitic N acting bridges linking platinum and the graphene/carbon black(the ratio graphene/carbon black = 2/3) hybrid support materials achieved the average size of platinum nanoparticles with(4.88 ± 1.79) nm. It improved the performance of the lower-temperature hydrogen fuel cell up to 0.934 W cm^(-2) at 0.60 V, which is 1.55 times greater than that of commercial Pt/C. Doping also enhanced the interaction between Pt and the support materials, and the resistance to corrosion, thus improving the durability of the low-temperature hydrogen fuel cell with a much lower decay of 10 mV at 0.80 A cm^(-2) after 30 k cycles of an in-situ accelerated stress test of catalyst degradation than that of 92 mV in Pt/C, which achieves the target of Department of Energy(<30 mV). Meanwhile,Pt/Nr EGO_(2)-CB_(3) remains 78% of initial power density at 1.5 A cm^(-2) after 5 k cycles of in-situ accelerated stress test of carbon corrosion, which is more stable than the power density of commercial Pt/C, keeping only 54% after accelerated stress test. | Zhaoqi Ji Jianuo Chen María Pérez-Page Zunmin Guo Ziyu Zhao Rongsheng Cai Maxwell T.P.Rigby Sarah J.Haigh Stuart M.Holmes | 2022 | Journal of Energy Chemistry2022，31，5： | 2 |
| 6 | Locally transplanted enteric glia improve functional and structural recovery in a rat model of spinal cord injury显示文摘<正>BACKGROUND:We have previously reported that adult enteric glia(EG) facilitate the growth of transected dorsal root axons into the uninjured spinal cord to form functional connections with their targets. OBJECTIVE:The present study investigated the effects of EG on spinal cord function,tissue injury, and axonal regeneration following transplantation into injured rat spinal cords,according to histological and functional outcomes. DESIGN,TIME AND SETTING:A randomized controlled animal experiment was performed at McMaster University,Canada from January 2006 to March 2008. MATERIALS:EG were isolated from rat intestine. METHODS:One week following spinal cord crush,female Wistar rats were injected with an EG suspension(2μL,1×10~5/μL,n=10) or with the same volume of fresh culture medium alone(control animals,n=11).The third group did not receive any injection following laminectomy and served as the sham-operated controls(n=5). MAIN OUTCOME MEASURES:Behavior was tested prior to transplantation and weekly following transplantation,with nine behavioral examinations in total.Open field,hind limb placement response, foot orientation response,and inclined plane test were utilized.Immediately following the final behavioral examination,spinal cord T_9 to L_1 segments were harvested for immunohistochemical and hematoxylin-eosin staining to determine astroglial scarring,axonal regeneration and spinal cord lesion size. RESULTS:Rats with EG transplantation exhibited significantly better locomotor function with reduced tissue damage,compared with the control rats.Cystic cavities were present 2 months after injury in spinal cords from both control groups.In contrast,rats injected with EG did not present with cystic lesions.In addition,the injury site consisted of cellular material and nerve fibers,and axonal regeneration was apparent,with dense labeling of neurofilament-positive axons within the injury site. Moreover,regenerating axons were intimately associated with transplanted EG CONCLUSION:These data indicated that EG enhanced functional improvement,which was associated with reduced tissue damage and axonal regeneration following transplantation into injured spinal cords. | Shucui Jiang Mohammad I. Khan James R. Bain Cai Jiang Christopher R. Hansebout Zesheng Yu Yuqing Liu Michel P, Rathbone | 2009 | Neural Regeneration Research2009，4，9： | 2 |
| 7 | Dynamic analysis of a flexible hub-beam system with tip mass显示文摘 | Cai G P Hong J Z Yang S X | 2005 | Mechanics Research Communications2005，32，2： | 1 |
| 8 | Endothelin-1 increases expression of cyclooxygenase-2 and production of interlukin-8 in hunan pulmonary epithelial cells显示文摘 | Peng H Chen P Cai Y | 2008 | Peptides2008，29，3： | 1 |
| 9 | Tomato leaf curl Guangxi virus is a distinct begomovirus species显示文摘 | Xu Y P Cai X Z Zhou X P | 2007 | European Journal of Plant Pathology2007，118，3： | 1 |
| 10 | Colloid Au-enhanced DNA immobilization for the dectrochemical detection of sequence-specific DNA显示文摘 | Xu C He P | 2001 | Journaof Electmanalytical Chemistry2001，510，12： | 1 |
| 11 | A two-pole 900/ 1800-MHz microstrip filter for dual-band applications显示文摘 | GUAN X MA Z CAI P | 2006 | Micowave Opt Tech Lett2006，48，7： | 1 |
| 12 | MAAN:A Multi-attribute Addressable Network for Grid Information Services显示文摘 | Cai Min Frank M Szekely P | 2004 | Journal of Grid Computing2004，2，1： | 1 |
| 13 | Tourist purchase decision involvement and information preferences显示文摘 | Cai L P Feng R M Breiter D | 2004 | Journal of Vacation Marketing2004，10，2： | 1 |
| 14 | Oral N-acetylcysteine attenuates pulmonary emphysema and alveolar septal cell apoptosis in smoking-induced COPD in rats 显示文摘 | Cai S Chen P Zhang C | 2009 | Respirology2009，14，3： | 1 |
| 15 | Photocatalytic degradation of phenol in aqueous nitrogen-doped TiO2 suspensions with various light sources 显示文摘 | Wang Z P Cai W M Hong X T | 2005 | Appl Catal B Environ2005，57，： | 1 |
| 16 | Shape effects of filamentsversus spherical particles in-ow and drug delivery显示文摘 | Yan G Dalhaimer P Cai S S | 2007 | NatureNanotechnology2007，2，3： | 1 |
| 17 | Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells显示文摘 | Cai JY Wu M Nelson KC Sternberg P Jones DP | 1999 | Invest Ophthalmol Vis Sci1999，40，： | 1 |
| 18 | Synthesis and properties of the geometrically controlled mixed-valence tetrahedral Ru^Ⅱ2 Ru^Ⅲ2 L6 cluster 显示文摘 | Cai P Li M Duan C | 2005 | Eur J Inorg Chem2005，，： | 1 |
| 19 | Indicator free DNA hybridization detection by impedance measurement based on the DNA-doped conducting polymer film formed on the carbon nanotube modified electrode显示文摘 | Cai H Xu Y He P G | 2003 | Electroanalysis2003，15，： | 1 |
| 20 | Cooperative branding for rural destinations显示文摘 | CAI L P | 2002 | Annals of Tourism Research2002，29，3： | 1 |
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