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| 1 | Systematic review of health-related quality of life after esophagectomy for esophageal cancer显示文摘This study is aimed to assess the long-term health-related quality of life(HRQL) of patients after esopha-gectomy for esophageal cancer in comparison with es-tablished norms,and to evaluate changes in HRQL during the different stages of follow-up after esopha-geal resection. A systematic review was performed bysearching medical databases(Medline,Embase andthe Cochrane Library) for potentially relevant studiesthat appeared between January 1975 and March 2011.Studies were included if they addressed the questionof HRQL after esophageal resection for esophage alcancer. Two researchers independently performed the study selection,data extraction and analysis processes.Twenty-one observational studies were included witha total of 1282(12-355) patients. Five studies were performed with short form-36(SF-36) and 16 with European Organization for Research and Treatment of Cancer(EORTC) QLQ C30(14 of them also utilized the disease-specific OES18 or its previous version OES24) .The analysis of long-term generic HRQL with SF-36showed pooled scores for physical,role and socialfunction after esophagectomy similar to United Statesnorms,but lower pooled scores for physical function,vitality and general health perception. The analysis of HRQL conducted using the Global EORTC C30 globalscale during a 6-mo follow-up showed that global scaleand physical function were better at the baseline. The symptom scales indicated worsened fatigue,dyspneaand diarrhea 6 mo after esophagectomy. In contrast,however,emotional function had significantly improved after 6 mo. In conclusion,short- and long-term HRQLis deeply affected after esophagectomy for cancer. The impairment of physical function may be a long-termconsequence of esophagectomy involving either the respiratory system or the alimentary tract. The short-and long-term improvement in the emotional function of patients who have undergone successful operationsmay be attributed to the impression that they have survived a near-death experience. | Marco Scarpa Stefano Valente Rita Alfieri Matteo Cagol Giorgio Diamantis Ermanno Ancona Carlo Castoro | 2011 | World Journal of Gastroenterology2011，17，42： | 15 |
| 2 | Impact of jejunostomy during esophagectomy for cancer on health related quality of life显示文摘Background: The aim of this study was to evaluate the impact of jejunostomy during esophagectomy for cancer on postoperative health-related quality of life(HRQL).Methods: We evaluate all consecutive patients who underwent esophagectomy for cancer at the surgical oncology unit of the Veneto Institute of Oncology(IOV-IRCCS) between January 2008 and March 2014. The primary outcome was HRQL, which was assessed using nine scales of EORTC C30 and OES18 questionnaires. General linear models were estimated to evaluate mean score difference(MD) of each selected scale in patients with and without jejunostomy, adjusting for clinically relevant confounders. The secondary outcomes were morbidity, hospital stay, postoperative weight loss and postoperative albumin impairment. Results: Jejunostomy was performed in 40 on 109 patients(41.3%) who participated in quality of life investigation. A clinically and statistically significantly worse eating at admission(P=0.009) became not clinically significant at 3 months after surgery(MD =9.1). Jejunostomy was associated to clinically and statistically significantly poorer emotional function(EF) at 3 months after surgery(MD =-15.6; P=0.04). Hospital stay was longer in jejunostomy group(median, 20 vs. 17 days, P=0.02).Conclusions: In our series patients who had a jejunostomy during esophagectomy had been selected for their risk for postoperative complication. However, their postoperative outcome was actually similar compared to those without jejunostomy. Nevertheless, jejunostomy was associated to clinically and statistically significantly poorer EF at 3 months after surgery. Therefore, patient candidate to esophagectomy and feeding jejunostomy should receive additional psychological support. | Marco Scarpa Francesco Cavallin Giulia Noaro Eleonora Pinto Rita Alfieri Matteo Cagol Carlo Castoro | 2014 | Chinese Journal of Cancer Research2014，26，6： | 2 |
| 3 | Programmed cell death 4 protein in esophageal cancer显示文摘 | Fassan M Cagol M Pennelli G | 2010 | Oncol Rep2010，24，1： | 1 |
| 4 | Low perioperative serum pre- albumin predicts early recurrence after curative pulmonary resection for non-smaU-cell lung cancer显示文摘 | Cavallin F Searpa M Cagol M | 2013 | World J Surg2013，36，12： | 1 |
| 5 | Potential advantages of loco-regional intra-arterial chemotherapy显示文摘 | Cagol P P Pasqual E Bacchetti S | | 0，，6： | 1 |
| 6 | Prophylactic thoracic duct mass liga- tion prevents chylothorax after transthoracic esophagectomy for cancer 显示文摘 | Cagol M Ruol A Castore C | 2009 | World J Surg2009，33，8： | 1 |
| 7 | Potential advantages of locoregional intra-arterial chemotherapy显示文摘 | Cagol P P Pasqual E Bacchetti S | 2006 | In Vivo2006，20，6： | 1 |
| 8 | Surgical complications do not affect longterm survival after esophagectomy for carcinoma of the thoracic esophagus and cardia显示文摘 | Ancona E Cagol M Epifani M | 2006 | J Am Coil Surg2006，203，5： | 1 |
| 9 | Surgical complications do not affect longterm survival after esophagetcomy for carcinoma of the thoracic esophagus and cardia显示文摘 | Ancona E Cagol M Epifani M | 2006 | J Am Coil Surg2006，203，： | 1 |
| 10 | Prophylactic thoracic duct mass ligation prevents chylothorax after transthoracic esophagectomy for cancer显示文摘 | Cagol M Ruol A Castoro C | 2009 | World J Surg2009，33，8： | 1 |
| 11 | Prophylaetie thoracic duet mass ligation prevents chylothorax after transthoraeic esophageetomy for eaneer显示文摘 | Cagol M Ruol A Castoro C | 2009 | World J Surg2009，33，8： | 1 |
| 12 | Complete clinical responseafter neoadjuvant chemoradiotherapy for squamous cell cancer of thethoracic oesophagus: is surgery always necessary-显示文摘 | Castoro C Scarpa M Cagol M | 2013 | J GastrointestSurg2013，17，8： | 1 |
| 13 | Surgical complica- tions do not affect longterm survival after esophagectomy for carcinoma of the thoracic esophagus and cardia显示文摘 | Ancona E Cagol M Epifani M | 2006 | J Am Coll Surg2006，203，5： | 1 |
| 14 | Complete clinical re- sponse after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic oesophagus:is surgery always necessary?显示文摘 | Castoro C Scarpa M Cagol M | 2013 | J Gastrointest Surg2013，17，8： | 1 |
| 15 | Programmed cell death 4(PDCD4)protein in esophageal cancer显示文摘 | Fassan M Cagol M Pennelli G | 2010 | Oncol Rep2010，24，1： | 1 |
| 16 | Programmed cell death 4 protein in esophageal cancer 显示文摘 | Fassan M Cagol M Pennelli G | 2010 | Oneol Rep2010，24，1： | 1 |
| 17 | Low perioperative serum prealbumin predicts early recurrence after curative pulmonary resection for non-small-cell lung cancer显示文摘 | Cavallin F Scarpa M Cagol M | 2013 | World J Surg2013，37，8： | 1 |
| 18 | Poten- tial advantages of locoregional intra- arterial chemotherapy 显示文摘 | Cagol PP Pasqual E Bacchetti S | 2006 | Iv Vivo2006，20，6： | 1 |
| 19 | Potential advantages of loco-re- gional intra-arterial chemotherapy 显示文摘 | Cagol PP Pasqual E Bacchetti S | 2006 | In Vivo2006，20，6： | 1 |
| 20 | Programmed cell death 4 protein in esophageal cancer显示文摘 | Fassan M Cagol M Pennelli G | 2010 | Oncology Reports2010，24，1： | 1 |
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