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| 1 | Recurrent headaches may be caused by cerebral toxoplasmosis显示文摘AIM: To establish seroprevalence and provide characteristics of Toxoplasma gondii(TG) infection in children with recurrent headaches. METHODS: The study was performed in 178 children aged 7-17 years admitted consecutively to the Department of Pediatric Neurology from November 2009 to July 2011. The children were surveyed with a questionnaire with the help and assistance of their parents and blood samples taken on admission were studied for the presence of specific anti-TG Ig M, Ig G antibodies and Ig G avidity using enzyme immunoassay Platelia Toxo Ig M, Ig G. RESULTS: The study showed that 19 children(8 boys, 11 girls; 8-17 years old, mean age 14.36 years) hadhigh serum anti-TG Ig G antibody levels(range: 32.2 > 240 UI/m L, mean 120.18 UI/m L; positive value for Ig G was ≥ 9 UI/m L). The avidity index(AI) ranged from 0.202 to 0.925(scale: ≥ 0.5 high AI). The results for Ig M antibodies were all negative and the obtained results ranged from 0.113 to 0.25 U/m L(mean = 0.191 IU/m L) and all values below 0.8 IU/m L were considered negative. The most frequent complaints found in the seropositive patients were headaches that affected the frontal(13 children), occipital(4) and parietal areas(5). Headaches usually had a pulsating(in 7 patients) and squeezing(6) character and rarely were piercing, dull or expanding. Interestingly, 8 children did not feel discomfort during the headaches, probably because they did not have sufficiently increased intracranial pressure yet. The headaches usually appeared 1-2 times/mo, lasted for 2-6 h, and had a mean intensity of 5.5 points in a 10 point subjective scale. The comorbidities included epilepsy(5 patients), various infections in 3 children(chronic eustachitis, chronic rhinitis, chronic purulent tonsillitis, streptococcal pharyngitis, meningitis, allergic diseases), disturbances of behavior, deficits of attention, and ocular and motor concentration disorders in 1 child. The electroencephalographic and neuroimaging studies performed in our patients had a very limited value in establishing cerebral toxoplasmosis.CONCLUSION: Ten point six seven percent of the studied children had markedly increased serum anti-TG Ig G antibodies and high AI indicated chronic infestation. It is suggested that tests for TG infection should be introduced to routine diagnostics in patients with recurrent headaches. | Joseph Prandota Anna Gryglas Aleksander Fuglewicz Agata Zesawska-Faleńczyk Barbara Ujma-Czapska Leszek Szenborn Janusz Mierzwa | 2014 | World Journal of Clinical Pediatrics2014，3，3： | 4 |
| 2 | Variations of phosphorus release from sediments in stratified lakes 显示文摘 | Czyk T G Casper P Koschel R | 1997 | Water Air Soil Pollut1997，99，14： | 1 |
| 3 | Variations of phosphorus release from sediments in stratified lakes显示文摘 | Czyk T G Casper P Koschel R | 1997 | Water Air Soil Pollut1997，99，14： | 1 |
| 4 | A Comparative Experimental Study of Biomass,Lignite and Hard Coal Steam Gasification显示文摘 | Smoli(n)ski A Howaniec N Sta(n)czyk K | | 0，，6： | 1 |
| 5 | Protection of me dical diagnostic laboratory workers against biohazards 显示文摘 | Kozajda A Szadkowska-Stan czyk I | 2011 | Med Pr2011，62，3： | 1 |
| 6 | Steam Co-gasification of Coal and Biomass Derived Chars with Synergy Effect as an Innovative Way of Hydrogen-rich Gas Production显示文摘 | Howaniec N Smoli(n)ski A Sta(n)czyk K | | 0，，22： | 1 |
| 7 | Fast track surgery particularly in case of patiEENts undergoing colonic resection显示文摘 | Morończyk DA Krasnodbski IW | | 0，，01： | 1 |
| 8 | In situ atomic force microscopy observation of change in thickness of nickel hydroxide layer on Ni electrode显示文摘 | Kowal A Niewiara R Pero(n)czyk B | | 0，，10： | 1 |
| 9 | Lactones 29 Enzyme resolution of racemic γ-lactones显示文摘 | Fajkowska M Obara R Wawrze(n)czyk C | | 0，，： | 1 |
| 10 | Cortical mapping by functional magnetic resonance imaging in patients with brain tumors显示文摘 | Majos A Tybor K Stefaczyk L | 2005 | Eur Radiol2005，15，6： | 1 |
| 11 | Use of alternative fuels in the Polish cement industry 显示文摘 | Mokrzycki E Uliasz-Boche czyk A Sarna M | 2003 | Applied Energy2003，74，1： | 1 |
| 12 | Variations of Phosphorus Release from Sediments in Stratified Lakes显示文摘 | Czyk TG Casper P Koschel R | 1997 | Water Air Soil Pollute1997，99，14： | 1 |
| 13 | Notch: A new player in MS mechanisms显示文摘 | Maciej Juryńczyk Krzysztof Selmaj | 2009 | Journal of Neuroimmunology2009，，1： | 1 |
| 14 | Pollution of water dur- ing underground coal gasification of hard coal and lignite 显示文摘 | Krzysztof Kapusta Krzysztof Stan czyk | 2011 | Fuel2011，，90： | 1 |
| 15 | Chemometric study of the exsitu underground coal gasification wastewater experimental data显示文摘 | Smoliński A Stańczyk K Kapusta K | 2012 | Water Air&Soil Pollution2012，223，9： | 1 |
| 16 | Bromodomain-containing subunits BRD1, BRD2, and BRD13 are required for proper functioning of SWI/SNF complexes in Arabidopsis显示文摘SWI/SNF chromatin remodelers are evolutionarily conserved multiprotein complexes that use the energy of ATP hydrolysis to change chromatin structure.A characteristic feature of SWI/SNF remodelers is the occurrence in both the catalytic ATPase subunit and some auxiliary subunits,of bromodomains,the protein motifs capable of binding acetylated histones.Here,we report that the Arabidopsis bromodomaincontaining proteins BRD1,BRD2,and BRD13 are likely true SWI/SNF subunits that interact with the core SWI/SNF components SWI3C and SWP73B.Loss of function of each single BRD protein caused early flowering but had a negligible effect on other developmental pathways.By contrast,a brd triple mutation(brdx3)led to more pronounced developmental abnormalities,indicating functional redundancy among the BRD proteins.The brdx3 phenotypes,including hypersensitivity to abscisic acid and the gibberellin biosynthesis inhibitor paclobutrazol,resembled those of swi/snf mutants.Furthermore,the BRM protein level and occupancy at the direct target loci SCL3,ABI5,and SVP were reduced in the brdx3 mutant background.Finally,a brdx3 brm-3 quadruple mutant,in which SWI/SNF complexes were devoid of all constituent bromodomains,phenocopied a loss-of-function mutation in BRM.Taken together,our results demonstrate the relevance of BRDs as SWI/SNF subunits and suggest their cooperation with the bromodomain of BRM ATPase. | Kamila Jarończyk Katarzyna Sosnowska Adam Zaborowski Piotr Pupel Maria Bucholc Ewelina Małecka Nina Siwirykow Paulina Stachula Roksana Iwanicka-Nowicka Marta Koblowska Andrzej Jerzmanowski Rafał Archacki | 2021 | Plant Communications2021，2，4： | 1 |
| 17 | Electronic tongue for the detection of taste-masking microencapsulation of active pharmaceutical substances显示文摘 | JA(N)CZYK M KUTYLA A SOLLOHUB K | | 0，，01： | 1 |
| 18 | Chemometric study of the ex-situ underground coal gasification wastewater experimental data显示文摘 | Adam Smoliński Krzysztof Stańczyk Krzysztof Kapusta | 2012 | Water Air Soil Pollut2012，223，： | 1 |
| 19 | Spontaneous NF-κB activation by autocrine TNFαsignaling:a computational analysis显示文摘 | P?kalski J Zuk PJ Kochańczyk M Junkin M Kellogg R | 2013 | PLo S One2013，8，78： | 1 |
| 20 | Semi-technical underground coal gasification(UCG)using the shaft method in Experimental Mine'Barbara'显示文摘 | Wiatowski M Stańczyk K | 2012 | Fuel2012，99，： | 1 |
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