| 4 | Immobilization of penicillin G acylase onto amino-modified silica hydrogel显示文摘Amino-modified silica hydrogel(N-MSHG)was prepared by a simple sol-gel processing via the cocondensation of commercial silica sol with 3-aminopropyltrieoxysilane.Penicillin G acylase(PGA),a model enzyme,was covalently immobilized onto the N-MSHG and then was used for the enzymatic synthesis of amoxicillin.The samples were characterized by Nitrogen sorption analysis,FT-IR and thermal gravimetric analysis(TGA).The results showed that the amino-modified gel was a mesoporous material with an average pore size of 12.64±0.17 nm.The immobilization process was efficient and the immobilized enzyme showed high catalytic efficiency.The yield of the synthesis of amoxicillin in aqueous media was 38%for 2.5 h.This sol-gel preparation is simple and shows prominent potential value in industrial processing. | Weibing DONG Huining HE Junbo GONG Victor CYANG | 2010 | Frontiers of Chemical Science and Engineering2010，4，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员