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| 1 | aunalysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza显示文摘 | Haibin Xu Jingyuan Song Hongmei Luo Yujun Zhang Qiushi Li Yingjie Zhu Jiang Xu Ying Li Chi Song Bo Wang Wei Sun Guoan Shen Xin Zhang Jun Qian Aijia Ji Zhichao Xu Xiang Luo Liu He Chuyuan Li Chao Sun Haixia Yah Guanghong Cui Xiwen Li Xian 'en Li Jianhe Wei Juyan Liu Yitao Wang Alice Hayward David Nelson Zemin Ning Reuben J. Peters Xiaoquan Qi Shilin Chen | 2016 | Molecular Plant2016,9,6: | 70 |
| 2 | Service-aware 6G:An intelligent and open network based on the convergence of communication,computing and caching显示文摘With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network. | Yiqing Zhou Ling Liu Lu Wang Ning Hui Xinyu Cui Jie Wu Yan Peng Yanli Qi Chengwen Xing | 2020 | Digital Communications and Networks2020,6,3: | 57 |
| 3 | A life support-based comprehensive treatment regimen dramatically lowers the in-hospital mortality of patients with fulminant myocarditis: a multiple center study显示文摘Fulminant myocarditis(FM) has unacceptable high mortality. This study aimed to evaluate the therapeutic efficacy of a life support-based comprehensive treatment regimen(LSBCTR), a completely novel treatment regimen, for FM. A total of 169 FM patients recruited from January 2008 to December 2018 were divided into two groups: patients receiving LSBCTR(81 cases),which includes(i) mechanical life support(positive pressure respiration, intra-aortic balloon pump with or without extracorporeal membrane oxygenation),(ii) immunomodulation therapy using sufficient doses of glucocorticoids and immunoglobulins, and(iii) application of neuraminidase inhibitors, and those receiving conventional treatment(88 cases). The endpoints were in-hospital death and heart-transplantation. Of all the population, 44 patients(26.0%) died in hospitals. Inhospital mortality was 3.7%(3/81) for LSBCTR group and 46.6%(41/88) for traditional treatment(P<0.001). Early application of LSBCTR, mechanical life support, neuraminidase inhibitors, and immunomodulation therapy significantly contributed to reduction in in-hospital mortality. This study describes a novel treatment regimen for FM patients that dramatically reduces inhospital mortality. Its generalization and clinical application will efficiently save lives although further optimization is needed.This study offers an insight that virus infection induced inflammatory waterfall results in cardiac injury and cardiogenic shock and is the therapeutic target. | Sheng Li Shengyong Xu Chenze Li Xiao Ran Guanglin Cui Mengying He Kun Miao Chunxia Zhao Jiangtao Yan Rutai Hui Ning Zhou Yan Wang Jiangang Jiang Jing Zhang Daowen Wang | 2019 | Science China(Life Sciences)2019,62,3: | 43 |
| 4 | Programmable time-domain digital-coding metasurface for non-linear harmonic manipulation and new wireless communication systems显示文摘Optical non-linear phenomena are typically observed in natural materials interacting with light at high intensities, and they benefit a diverse range of applications from communication to sensing. However,controlling harmonic conversion with high efficiency and flexibility remains a major issue in modern optical and radio-frequency systems. Here, we introduce a dynamic time-domain digital-coding metasurface that enables efficient manipulation of spectral harmonic distribution. By dynamically modulating the local phase of the surface reflectivity, we achieve accurate control of different harmonics in a highly programmable and dynamic fashion, enabling unusual responses, such as velocity illusion. As a relevant application, we propose and realize a novel architecture for wireless communication systems based on the time-domain digital-coding metasurface, which largely simplifies the architecture of modern communication systems, at the same time yielding excellent performance for real-time signal transmission. The presented work, from new concept to new system, opens new pathways in the application of metamaterials to practical technology. | Jie Zhao Xi Yang Jun Yan Dai Qiang Cheng Xiang Li Ning Hua Qi Jun Chen Ke Guo Dong Bai Shuo Liu Shi Jin Andrea Alù Tie Jun Cui | 2019 | National Science Review2019,6,2: | 46 |
| 5 | Sleep and Cognitive Abnormalities in Acute Minor Thalamic Infarction显示文摘In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction(AMTI), we enrolled 27 patients with AMTI and 12 matched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography(PSG) were performed on days 14 and 90 post-stroke. Compared to healthy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3;more sleep-related breathing disorders occurred; and cognitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance,sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients. | Wei Wu Linyang Cui Ying Fu Qianqian Tian Lei Liu Xuan Zhang Ning Du Ying Chen Zhijun Qiu Yijun Song Fu-Dong Shi Rong Xue | 2016 | Neuroscience Bulletin2016,32,4: | 28 |
| 6 | Requirement and Functional Redundancy of Ib Subgroup bHLH Proteins for Iron Deficiency Responses and Uptake in Arabidopsis thaliana显示文摘在 Arabidopsis 的 bHLH 基因家庭的 Ib 亚群包含四个成员(AtbHLH38, AtbHLH39, AtbHLH100,和 AtbHLH101 ) 。AtbHLH38 和 AtbHLH39 以前被证实与象 FER 一样铁缺乏交往导致的抄写因素(合适) ,直接在 ferricchelate reductase FRO2 和高亲密关系的铁的铁 transporter IRT1 的表示的激活工作。在这个工作,我们在铁缺乏回答和举起的规定描绘了 AtbHLH100 和 AtbHLH101 的功能。酵母二混血儿的分析和双分子的荧光互补试金证明 AtbHLH100 和 AtbHLH101 能交往与合适。AtbHLH100 或 AtbHLH101 与的双表示装入激活的酵母房间 FRO2 和 IRT1 的倡导者驾驶的 GUS 表示。工厂 overexpressing 与 AtbHLH101 结合了在根显示出 FRO2 和 IRT1 的组成的表示,并且在射击积累了更多的铁。进一步, AtbHLH38, AtbHLH39, AtbHLH100,和 AtbHLH101 的单个、双、三倍的猛烈异种被产生并且描绘。在根的 FRO2 和 IRT1 表示和在射击的铁内容更急速地比双的可得到的其它和四基因的三倍的异种的在 AtbHLH39, AtbHLH100,和 AtbHLH101 的三倍的猛烈异种被减少。象在在铁缺乏下面的多重猛烈异种的 FRO2 和 IRT1 的表示一样的生理的回答的比较表明 AtbHLH100, AtbHLH38, AtbHLH101,和 AtbHLH39 在铁缺乏回答和举起起了逐渐地增加的重要作用。一起拿所有,我们断定四 Ib 亚群 bHLH 蛋白质在 Arabidopsis 为铁缺乏回答和举起的激活与微分意义被要求并且拥有冗余的功能。 | Ning Wang Yan Cui Yi Liu Huajie Fan Juan Du Zongan Huang Youxi Yuan Huilan Wu Hong-Qing Ling | 2013 | Molecular Plant2013,6,2: | 26 |
| 7 | Anti-cd TCR antibody-expanded cd T cells:a better choice for the adoptive immunotherapy of lymphoid malignancies显示文摘Cell-based immunotherapy for lymphoid malignancies has gained increasing attention as patients develop resistance to conventional treatments.cd T cells,which have major histocompatibility complex(MHC)-unrestricted lytic activity,have become a promising candidate population for adoptive cell transfer therapy.We previously established a stable condition for expanding cd T cells by using anti-cd T-cell receptor(TCR)antibody.In this study,we found that adoptive transfer of the expanded cd T cells to Daudi lymphoma-bearing nude mice significantly prolonged the survival time of the mice and improved their living status.We further investigated the characteristics of these antibody-expanded cd T cells compared to the more commonly used phosphoantigen-expanded cd T cells and evaluated the feasibility of employing them in the treatment of lymphoid malignancies.Slow but sustained proliferation of human peripheral blood cd T cells was observed upon stimulation with anti-cd TCR antibody.Compared to phosphoantigen-stimulated cd T cells,the antibody-expanded cells manifested similar functional phenotypes and cytotoxic activity towards lymphoma cell lines.It is noteworthy that the anti-cd TCR antibody could expand both the Vd1 and Vd2 subsets of cd T cells.The in vitro-expanded Vd1 T cells displayed comparable tumour cell-killing activity to Vd2 T cells.Importantly,owing to higher C–C chemokine receptor 4(CCR4)and CCR8 expression,the Vd1 T cells were more prone to infiltrate CCL17-or CCL22-expressing lymphomas than the Vd2 T cells.Characterizing the peripheral blood cd T cells from lymphoma patients further confirmed that the anti-cd TCR antibody-expanded cd T cells could be a more efficacious choice for the treatment of lymphoid malignancies than phosphoantigen-expanded cd T cells. | Jianhua Zhou Ning Kang Lianxian Cui Denian Ba Wei He | 2012 | Cellular & Molecular Immunology2012,9,1: | 17 |
| 8 | Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality显示文摘Severe fever with thrombocytopenia syndrome (SFTS),an emerging tick-borne infectious disease caused by a novel phlebovirus (SFTS virus, SFTSV), was listed among the top 10 priority infectious diseases by the World Health Organization due to its high fatality of 12%-50% and possibility of pandemic transmission. Currently, effective anti-SFTSV intervention remains unavailable. Here, by screening a library of FDA-approved drugs, we found that benidipine hydrochloride, a calcium channel blocker (CCB), inhibited SFTSV replication in vitro. Benidipine hydrochloride was revealed to inhibit virus infection through impairing virus internalization and genome replication. Further experiments showed that a broad panel of CCBs, including nifedipine, inhibited SFTSV infection. The anti-SFTSV effect of these two CCBs was further an a lyzed in a humanized mouse model in which CCB treatment resulted in reduced viral load and decreased fatality rate. Importantly, by performing a retrospective clinical investigation on a large cohort of 2087 SFTS patients, we revealed that nifedipine administration enhaneed virus clearance, improved clinical recovery, and remarkably reduced the case fatality rate by >5-fold. These findings are highly valuable for developing potential host-oriented therapeutics for SFTS and other lethal acute viral infections known to be inhibited by CCBs in vitro. | Hao Li Lei-Ke Zhang Shu-Fen Li Shao-Fei Zhang Wei-Wei Wan Yu-Lan Zhang Qi-Lin Xin Ke Dai Yuan-Yuan Hu Zhi-Bo Wang Xiang-Tao Zhu Yu-Jie Fang Ning Cui Pan-He Zhang Chun Yuan Qing-Bin Lu Jie-Ying Bai Fei Deng Geng-Fu Xiao Wei Liu Ke Peng | 2019 | Cell Research2019,29,9: | 15 |
| 9 | Adult intussusception:A retrospective review of 41 cases显示文摘AIM:To optimize the preoperative diagnosis and surgical management of adult intussusception (AI).METHODS:A retrospective review of the clinical features,diagnosis,management and pathology 41 adult patients with postoperative diagnoses of intussusception was conducted.RESULTS:Forty-one patients with 44 intussusceptions were operated on,24.4% had acute symptoms,24.4% had subacute symptoms,and 51.2% had chronic symptoms.70.7% of the patients presented with intestinal obstruction.There were 20 enteric,15 ileocolic,eight colocolonic and one sigmoidorectal intussusceptions.65.9% of intussusceptions were diagnosed preoperatively using a computed tomography (CT) scan (90.5% accurate) and ultrasonography (60.0% accurate,rising to 91.7% for patients who had a palpable abdominal mass).Coloscopy located the occupying lesions of the lead point of ileocolic,colocolonic and sigmoidorectal intussusceptions.Four intussusceptions in three patients were simply reduced.Twenty-one patients underwent resection after primary reduction.There was no mortality and anastomosis leakage perioperatively.Except for one patient with multiple small bowel adenomas,which recurred 5 mo after surgery,no patients were recurrent within 6 mo.Pathologically,54.5% of the intussusceptions had a tumor,of which 27.3% were malignant.9.1% comprised nontumorous polyps.Four intussusceptions had a gastrojejunostomy with intestinal intubation,and four intussusceptions had no organic lesion.CONCLUSION:CT is the most effective and accurate diagnostic technique.Colonoscopy can detect most lead point lesions of non-enteric intussusceptions.Intestinal intubation should be avoided. | Ning Wang Xing-Yu Cui Yu Liu Jin Long Yuan-Hong Xu Ren-Xuan Guo Ke-Jian Guo | 2009 | World Journal of Gastroenterology2009,15,26: | 15 |
| 10 | Clinical significance of HOTAIR expression in colon cancer显示文摘AIM: To detect the expression of the long noncoding RNA HOTAIR in colon cancer and analyze its relationship with clinicopathological parameters of colon cancer. METHODS: Total RNA was extracted from 80 colon cancer tissues and matched tumor-adjacent normal colon tissues and reverse transcribed. Quantitative polymerase chain reaction was used to detect the expression of HOTAIR. The relationship between the expression of HOTAIR and clinicopathological parameters of colon cancer was analyzed. RESULTS: The expression of HOTAIR was significantly higher in colon cancer tissues than in matched tumoradjacent normal colon tissues(P < 0.05). HOTAIR expression was significantly higher in cases with lymph node metastasis than in those without metastasis; in lowly differentiated and undifferentiated cases than in highly and moderately differentiated cases; and in stages Ⅲ + Ⅳ cases than in stages?Ⅰ?+ Ⅱ cases(P < 0.05).CONCLUSION: HOTAIR expression is upregulated in colon cancer, suggesting that HOTAIR plays an important role in the tumorigenesis, development and metastasis of colon cancer. HOTAIR may act as an oncogene and represents a new molecular target for the treatment of colon cancer. | Zhi-Fen Luo Dan Zhao Xi-Qing Li Yong-Xia Cui Ning Ma Chuang-Xin Lu Ming-Yue Liu Yun Zhou | 2016 | World Journal of Gastroenterology2016,22,22: | 14 |
| 11 | The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats显示文摘Objective To explore the Intervention effect of Rosiglitozone in ovarian fibrosis of PCOS rats.Methods 60 female SD rats were randomly divided into 3 groups:control group,model group and treatment group.The model and treatment groups were established by subcutaneous injection of DHEA,while the treatment group was given RGZ.The serum hormone values,pathohistology of ovarian structure of rats,ovarian ultrastructure and the expressions of TGF-β 1 and CTGF were detected.Results The PCOS model was established successfully.The expression intensity of TGF-β 1 and CTGF in Oocytes of the PCOS groups was 9.545±2.954 and 9.665±2.400,respectively and was significantly higher than that of the control group 6.636±2.264 and 7.036±2.133;after treatment with rosiglitazone,the expression was significantly decreased 6.980±2.421 and 6.642±2.721 as compared with that of the model group (P<0.05,P<0.001).The values in serum of the PCOS groups were 3.749±2.054 and 0.265±0.129,and 1.914±1.801 and 0.096±0.088 in the control group which had statistically significant difference (P<0.05,P<0.001).After treatment with rosiglitazone,the values were 2.3100±1.825 and 0.112±0.187 and were significantly different with those of the model group (P<0.05,P<0.001).Conclusion TGF-β 1 and CTGF play an important role in the development of ovary fibrosis in PCOS.However,RGZ may postpone the development of fibrosis by decreasing the levels of TGF-β 1 and CTGF. | MIAO Zhu Lin GUO Liang WANG Yong Xia CUI Rong YANG Ning HUANG Mi Qiong QIN Wei Bing CHEN Jin LI Hong Mei WANG Zi Neng WEI Xiang Cai | 2012 | Biomedical and Environmental Sciences2012,25,1: | 14 |
| 12 | The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence. | Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023,66,8: | 14 |
| 13 | Spatial distribution and focal mechanism solutions of the Wenchuan earthquake series:Results and implications显示文摘We relocate the spatial distribution of the devastating 12 May 2008 Wenchuan earthquake and its aftershocks.The relocation database is obtained from 89 stations deployed by the China Earthquake Administration,including 54 525 seismograms from 1 376 local earthquakes over MS3.5 between 12 May 2008 and 3 August 2008.The cross-correlation technique used in this paper has greatly improved the relocation precision by giving much more accurate P-wave differential travel-time measurements than those obtained from routinely picked phase onsets.At the same time,we pick P-wave polarity observations of the Wenchuan earthquake series (hereafter referred to as WES) from 1 023 stations in China and 59 IRIS (Incorporated Research Institutions of Seismology) stations.Then,employing a newly developed program CHNYTX,we obtain 83 well-determined focal mechanism solutions (hereafter referred to as FMSs).Based on spatial distribution and FMSs of the WES,we draw following conclusions:(1) The region near the main shock exhibits a buried low-angle northwest-dipping seismic zone with the main shock at its upper end and two conjugated seismic zones dipping southeast with roughly equal dip-angle;(2) The compressional directions of all kinds of FMSs of the WES are subhorizontal,which reflects the dominant stress in this area is compressional;(3) The principal compressional direction of the regional stress around Wenchuan is roughly perpendicular to the strike of Beichuan-Yingxiu fault,while around Qingchuan it is roughly parallel to the strike of Qingchuan fault.In intermediate part of the Longmenshan area,the principal compressional direction of the stress should be in-between;(4) The possibly existed molten materials in the lower crust of Songpan-Garze terrain have small contribution to the local stress state in Longmenshan area.The listric geometries of the Longmenshan faults most probably resulted from subhorizontal compression along NW-SE direction in history. | Chen Cai Chunquan Yu Kai Tao Xingping Hu Yuan Tian Hao Zhang Xiaofeng Cui Jieyuan Ning | 2011 | Earthquake Science2011,24,1: | 13 |
| 14 | Function identification of miR482b, a negative regulator during tomato resistance to Phytophthora infestans显示文摘Tomato is an important horticultural and economic crop cultivated worldwide.As Phytophthora infestans becomes a huge threat to tomato production,it is necessary to study the resistance mechanisms of tomato against P.infestans.Our previous research has found that miR482 might be involved in tomato–P.infestans interaction.In this study,miR482b precursor was cloned from Solanum pimpinellifolium“L3708”and miR482b was shown to decrease in abundance in tomato following P.infestans infection.Compared to wild-type tomato plants,tomato plants that overexpressed miR482b displayed more serious disease symptoms after P.infestans infection,with more necrotic cells,longer lesion diameters,and increased P.infestans abundance.Meanwhile,silencing of miR482b was performed by short tandem target mimic(STTM),resulting in enhancement of tomato resistance to P.infestans.Using miRNA and degradome data sets,NBS–LRR disease-resistance genes targeted by miR482b were validated.Negative correlation between the expression of miR482b and its target genes was found in all miR482b-overexpressing and-silencing tomato plants.Our results provide insight into tomato miR482b involved in the response to P.infestans infection,and demonstrate that miR482b–NBS–LRR is an important component in the network of tomato–P.infestans interaction. | Ning Jiang Jun Meng Jun Cui Guangxin Sun Yushi Luan | 2018 | Horticulture Research2018,5,1: | 13 |
| 15 | Tomato lncRNA23468 functions as a competing endogenous RNA to modulate NBS-LRR genes by decoying miR482b in the tomato-Phytophthora infestans interaction显示文摘Our previous studies indicated that tomato miR482b could negatively regulate the resistance of tomato to Phytophthora infestans and the expression of miR482b was decreased after inoculation with P.infestans.However,the mechanism by which the accumulation of miR482b is suppressed remains unclear.In this study,we wrote a program to identify 89 long noncoding RNA(lncRNA)-originated endogenous target mimics(eTMs)for 46 miRNAs from our RNA-Seq data.Three tomato lncRNAs,lncRNA23468,lncRNA01308 and lncRNA13262,contained conserved eTM sites for miR482b.When lncRNA23468 was overexpressed in tomato,miR482b expression was significantly decreased,and the expression of the target genes,NBS-LRRs,was significantly increased,resulting in enhanced resistance to P.infestans.Silencing lncRNA23468 in tomato led to the increased accumulation of miR482b and decreased accumulation of NBS-LRRs,as well as reduced resistance to P.infestans.In addition,the accumulation of both miR482b and NBS-LRRs was not significantly changed in tomato plants that overexpressed lncRNA23468 with a mutated eTM site.Based on the VIGS system,a target gene of miR482b,Solyc02g036270.2,was silenced.The disease symptoms of the VIGS-Solyc02g036270.2 tomato plants were in accordance with those of tomato plants in which lncRNA23468 was silenced after inoculation with P.infestans.More severe disease symptoms were found in the modified plants than in the control plants.Our results demonstrate that lncRNAs functioning as eTMs may modulate the effects of miRNAs in tomato and provide insight into how the lncRNA23468-miR482b-NBS-LRR module regulates tomato resistance to P.infestans. | Ning Jiang Jun Cui Yunsheng Shi Guanglei Yang Xiaoxu Zhou Xinxin Hou Jun Meng Yushi Luan | 2019 | Horticulture Research2019,6,1: | 12 |
| 16 | Narrow-band imaging in the diagnosis of early esophageal cancer and precancerous lesions显示文摘最近的年里的背景,在中国的食道的癌症的发生有 increased.The 钥匙点因为提起幸存率在成像( NBI )能提高的一个早stage.Narrow乐队是诊断和治疗没有 staining.This 学习的食管的粘膜的对比试图在诊断探索 NBI 的价值早食道癌症和癌症前期的 lesions.Methods 食管与平常的内视镜检查法和 NBI endoscopy.Pit 模式和血 capilla | HUANG Liu-ye CUI Jun WU Cheng-rong LIU Yun-xiang XU Ning | 2009 | Chinese Medical Journal2009,,7: | 12 |
| 17 | Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China:focus on the safety显示文摘Background:World Health Organization recommends countries introducing new drug and short treatment regimen for drug resistant tuberculosis(DR-TB)should develop and implement a system for active pharmacovigilance that allows for detection,reporting and management of adverse events.The aim of the study is to evaluate the frequency and severity of adverse events(AEs)of bedaquiline-containing regimen in a cohort of Chinese patients with multidrug-resistant(MDR)/extensively drug-resistant(XDR)-TB based on active drug safety monitoring(aDSM)system of New Drug Introduction and Protection Program(NDIP). | Jing-Tao Gao Juan Du Gui-Hui Wu Yi Pei Meng-Qiu Gao Leonardo Martinez Lin Fan Wei Chen Li Xie Yu Chen Hua Wang Long Jin Guo-Bao Li Pei-Lan Zong Yu Xiong Qian-Hong Wu Ming-Wu Li Xiao-Feng Yan Yan-Fang Miao Qing-Shan Cai Xin-Jie Li Da-Peng Bai Shu-Jun Geng Guo-Li Yang Pei-JunTang Yi Zeng Xiao-Hong Chen Tong-Xia Li Cui Cai Yun Zhou Ma Zhuo Jian-Yun Wang Wen-Long Guan Lin Xu Ji-Chan Shi Wei Shu Li-Li Cheng FeiTeng Yu-Jia Ning Shi-Heng Xie Yu-Xian Sun Li-Jie Zhang Yu-Hong Liu | 2021 | Infectious Diseases of Poverty2021,10,2: | 11 |
| 18 | Space-Air-Ground Integrated Network (SAGIN) for 6G: Requirements, Architecture and Challenges显示文摘As the fifth-generation(5G)mobile communication network may not meet the requirements of emerging technologies and applications,including ubiquitous coverage,industrial internet of things(IIoT),ubiquitous artificial intelligence(AI),digital twins(DT),etc.,this paper aims to explore a novel space-air-ground integrated network(SAGIN)architecture to support these new requirements for the sixth-generation(6G)mobile communication network in a flexible,low-latency and efficient manner.Specifically,we first review the evolution of the mobile communication network,followed by the application and technology requirements of 6G.Then the current 5G non-terrestrial network(NTN)architecture in supporting the new requirements is deeply analyzed.After that,we proposes a new flexible,low-latency and flat SAGIN architecture,and presents corresponding use cases.Finally,the future research directions are discussed. | Huanxi Cui Jun Zhang Yuhui Geng Zhenyu Xiao Tao Sun Ning Zhang Jiajia Liu Qihui Wu Xianbin Cao | 2022 | China Communications2022,19,2: | 11 |
| 19 | LA-ICP-MS Zircon U-Pb Geochronology of the Fine-grained Granite and Molybdenite Re-Os Dating in the Wurinitu Molybdenum Deposit,Inner Mongolia,China显示文摘The Wurinitu molybdenum deposit,located in Honggor,Sonid Left Banner of Inner Mongolia,China,is recently discovered and is considered to be associated with a concealed fine-grained granite impregnated with molybdenite.The wall rocks are composed of Variscan porphyritic-like biotite granite and the Lower Ordovician Wubin'aobao Formation.LA-ICP-MS zircon U-Pb dating of the fine-grained granite reveals two stages of zircons,one were formed at 181.7±7.4 Ma and the other at 133.6±3.3 Ma.The latter age is beli... | Cui LIU Jinfu DENG Weiqiong KONG Liquan XU Guochun ZHAO Zhaohua LUO Ning LI | 2011 | Acta Geologica Sinica(English Edition)2011,85,5: | 10 |
| 20 | Luteolin-7-diglucuronide attenuates isoproterenolinduced myocardial injury and fibrosis in mice显示文摘心肌的损害和随后的 fibrotic 改变损害正常的心建筑学并且引起心脏的机能障碍。氧化应力在心脏的机能障碍的心脏的损害和前进的致病作为一个关键播放器被认出了,并且支持纤维变性。在当前的学习,我们调查了是否 luteolin-7-diglucuronide (L7DG ) ,一种自然地发生的抗氧化剂在可食的植物发现了,能稀释导致的 isoproterenol (ISO ) 在老鼠和内在的机制的心肌的损害和纤维变性。心肌的损害和纤维变性经由 ISO 的注射在老鼠被导致(5 mg 瑡湩 ? 湥潤汰獡業? ?????????? ? 椠 ' 諗珮 I? 敲数晲獵潩吗?? | Bing-bing NING Yong ZHANG Dan-dan WU Jin-gang CUI Li LIU Pei-wei WANG Wen-jian WANG Wei-liang ZHU Yu CHEN Teng ZHANG | 2017 | Acta Pharmacologica Sinica2017,38,3: | 10 |