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| 1 | The Cytotoxic Constituents from Marine-derived Streptomyces 3320^(#)显示文摘现在的工作从 marine-derivedstreptomyces 学习化学成分 3320 ~# 并且他们的反肿瘤活动。酵素肉汤 of3320~# 的 n-BuOH 摘录在用 antitoumor 活动分开混合物的硅石胶化, Sephadex LH-20, ODS 列和 HPLC 上被用色层法分离。他们的结构用红外被识别,紫外, NMR, MSspectroscopic 技术并且与出版数据相比。isolates 的反肿瘤活动是用 SRB 方法和流动 cytometry 试金的 assayed,对哺乳动物的 tsFT210 房间在轻显微镜下面与房间的词法观察伴随了。十混合物,出租机动三轮车--(翼列伊) 1 ,出租机动三轮车--( Ala-Ile ) 2 ,出租机动三轮车--( Ala-Val ) 3 ,出租机动三轮车--(Phe-职业人员) 4 ,出租机动三轮车--( Phe-Gly ) 5 ,出租机动三轮车--(列伊职业人员) 6 , 1-methyl-1 , 2 , 3 ,4-tetrahydro-β- carboline-3-carboxylic 酸 7 ,N-( 4-hydroxyphenethyl )乙酰胺 8 ,4-methyoxy-1-( 2-hydroxy )乙醇苯 9 并且 uridine 10 ,从 streptomyces 的酵素肉汤被孤立 3320 ~#。在他们之中,加重 6, 7, 8 和 10 对有 IC_(50 ) 的 tsFT210 房间的显示出的有势力 cytotoxicity 3.6, 7.2, 5.2 和 1.6 mmolL~ 珍视(-1), 分别地。加重 8,在 2.0 mmolL~ 下面的 10 也展出的 apoptosis 导致活动(-1) 。混合物 6,7,8 和 10 是原则简历为海洋的 streptomyces 的 theantitumor 活动负责的活跃成分 3320 ~# 。化合物 7 第一次从这种被孤立。 | REN Hong GU Qianqun CUI Chengbin ZHU Weiming | 2006 | Journal of Ocean University of China2006,5,1: | 4 |
| 2 | Construction of a Metagenomic DNA Library of Sponge Symbionts and Screening of Antibacterial Metabolites显示文摘为了学习简历,活跃代谢物由导出海绵的未耕作的共生者生产了,海绵 Gelliodes gracilis 的共生者的一个 metagenomic DNA 图书馆被构造。DNA 的平均尺寸在图书馆插入是 20kb。这个图书馆用纸圆盘 assaying 为抗菌素活动被屏蔽。二克隆对小球菌 tetragenus 显示了抗菌剂活动。这二克隆的代谢物通过 HPLC 被分析。结果证明他们的代谢物与主人 E 的那些相当不同。包含向量 pHZ132 的关口 i DH5 α和主人。这研究可以介绍一条新途径给探索简历海绵共生者的活跃代谢物。 | CHEN Juan ZHU Tianjiao LI Dehai CUI Chengbin FANG Yuchun LIU Hongbing LIU Peipei GU Qianqun ZHU Weiming | 2006 | Journal of Ocean University of China2006,5,2: | 3 |
| 3 | General synthesis of hollow mesoporous conducting polymers by dual-colloid interface co-assembly for high-energy-density micro-supercapacitors显示文摘Rational design and precise regulation over the morphology, structure, and pore size of functional conducting mesoporous polymers with enriched active sites and shorten electron–ion transport pathway are extremely important for developing high-performance micro-supercapacitors (MSCs), but still remain a great challenge. Herein, a general dual-colloid interface co-assembly strategy is proposed to fabricate hollow mesoporous polypyrrole nano-bowls (mPPy-nbs) for high-energy-density solid-state planar MSCs. By simply adjusting the size of block copolymer micelles, the diameter of polystyrene nanospheres and the amount of pyrrole monomer, mesopore size of the shell, void and shell thickness of mPPy-nbs can be simultaneously controlled. Importantly, this strategy can be further utilized to synthesize other hollow mesoporous polymers, including poly(tris(4-aminophenyl)amine), poly(1,3,5-triaminobenzene) and their copolymers, demonstrative of excellent universality. The structurally optimized mPPy-nb exhibits high specific surface area of 122 m^(2) g^(−1)and large capacitance of 225 F g^(−1) at 1 mV s^(−1). Furthermore, the MSCs assembled by mPPy-nbs deliver impressive volumetric capacitance of 90 F cm^(−3) and energy density of 2.0 mWh cm^(−3), superior to the most reported polymers-based MSCs. Also, the fabricated MSCs present excellent flexibility with almost no capacitance decay under varying bending states, and robust serial/parallel self-integration for boosting voltage and capacitance output. Therefore, this work will inspire the new design of mesoporous conducting polymer materials toward high-performance microscale supercapacitive devices. | Jing Cui Fei-Fei Xing Hao Luo Jie-Qiong Qin Yan Li Yonghui Zhong Facai Wei Jianwei Fu Chengbin Jing Jiangong Cheng Zhong-Shuai Wu Shaohua Liu | 2021 | Journal of Energy Chemistry2021,30,11: | 3 |
| 4 | Carbazole alkaloids as new cell cycle inhibitor and apopTosis inducers from Clauaena dunniana Levl 显示文摘 | CUI Chengbin YAN Shaoyu CAI Bing | 2002 | Journal of Asian Natural Products Research2002,4,4: | 1 |
| 5 | Hollow Bio-derived Polymer Nanospheres with Ordered Mesopores for Sodium-Ion Battery显示文摘Bio-inspired hierarchical self-assembly provides elegant and powerful bottom-up strategies for the creation of complex materials.However,the current self-assembly approaches for natural bio-compounds often result in materials with limited diversity and complexity in architecture as well as microstructure.Here,we develop a novel coordination polymerization-driven hierarchical assembly of micelle strategy,using phytic acid-based natural compounds as an example,for the spatially controlled fabrication of metal coordination bio-derived polymers.The resultant ferric phytate polymer nanospheres feature hollow architecture,ordered meso-channels of^12 nm,high surface area of 401 m2 g−1,and large pore volume of 0.53 cm3 g−1.As an advanced anode material,this bio-derivative polymer delivers a remarkable reversible capacity of 540 mAh g−1 at 50 mA g−1,good rate capability,and cycling stability for sodium-ion batteries.This study holds great potential of the design of new complex bio-materials with supramolecular chemistry. | Yan Ai Yuxiu You Facai Wei Xiaolin Jiang Zhuolei Han Jing Cui Hao Luo Yucen Li Zhixin Xu Shunqi Xu Jun Yang Qinye Bao Chengbin Jing Jianwei Fu Jiangong Cheng Shaohua Liu | 2020 | Nano-Micro Letters2020,12,3: | 1 |
| 6 | EXPRESSION OF CALCITONING GENE-RELATED PEPTIDE IN VASCULAR SMOOTH MUSCLE CELLS BY RETROVIRUS-MEDIATED GENE TRANSFER显示文摘Background:The contemporary treatment of coronary athero-occlusive disease bypercutaneous transluminal coronary angioplasty is hampered by maladaptive woundhealing,resulting in significant failure rates.Morbid sequelae include smooth musclecell(SMC)hyperplesia and restenosis due to vascular neointimal formation.Calcitoningene-related peptide(CGRP)has been proposed as a potential therapeutic neuopeptide forintimal hyperplastic vascular disease.Methods and Results:In this study,we investigated CGRP gene expression in culturedrat thoracic arterial smooth muscle cells(SMCs)A replication-defective,recombinantretrovirus containing human α-CGRP cDNA(termed pRCGRP)was constructed and usedto infect SMCs in culture.Following selection with G418,cells traneduced by pRCGRPwere found to express CGRP and stable transfer of CGRP in SMCs was achieved withretroviral vector.CGRP gene expression was observed only when cultured SMCs weretransduced with vectors containing the CGRP cDNA No evidence of similar geneexpression was observed in nontranfected or empty vector transfected SMCs CGRPexpressed in the transduced SMCs was secreted into culture medium and was detected byradioimmunoassay(RIA).The highest level of CGRP gene product reached 18.2±0.6pM,whereas that of normal and control group were undectable.Conclusions:The fact that a recombinant gene can be readily inserted and efficientlyexpressed in vascular smooth muscle cells suggests that CGRP gene may be served as apromising candidate gene for gene therapy in atharosclerosis and restenosis.Retroviralmediated CGRP gene transfer may he used to treat atherosclerosis and restenosis. | Junfeng CUI Xiaofeng JIN Tong Zhang Yuqing HUO Chengbin XU people’s Hospital,Beijing Medical University,Beijing 100044,China Address for correspondence:Professor Xu Cheng-bin,Department of Cardiology,People’s Hospital,Beijing Medical Universy,Beijing 100044,Tel:68314422-5347 | 1998 | 中国介入心脏病学杂志1998,6,4: | 1 |
| 7 | Carbazole alkaloids as new cell cycle inhibitor and apopTosis inducers from Clausena dunniana Levi显示文摘 | CUI Chengbin YAN Shaoyu CA1 Bing | 2002 | Journal of Asian Natural Products Research2002,4,4: | 1 |
| 8 | Two-dimensional mesoporous sensing materials显示文摘Two-dimensional mesoporous materials combing ultrathin nanosheet morphology with well-defined mesoporous structures,are now emerging and becoming increasingly important for their promising applications in energy storage,electronic devices,electrocatalysts and so on.Here,we synthesized a kind of polypyrrole-based two-dimensional mesoporous materials with uniform pore size,ultrathin thickness and high surface area.Serving for electrochemical NH3 sensor,they exhibited a fast response and high sensitivity.Therefore,our study would promote much interest in design of new materials for gas sensor applications. | Yu Wen Facai Wei Wenqian Zhang Anyang Cui Jing Cui Chengbin Jing Zhigao Hu Qingguo He Jianwei Fu Shaohua Liu Jiangong Cheng | 2020 | Chinese Chemical Letters2020,31,2: | 0 |
| 9 | Cerebrovascular hemodynamics in patients with cerebral arteriosclerosis显示文摘The present study observed hemodynamic changes in 26 patients with cerebral arteriosclerosis using a cerebral circulation dynamics detector and transcranial Doppler. In patients with cerebral arteriosclerosis the blood supply and flow rate in the bilateral carotid arteries and the blood flow rate in the anterior cerebral and middle cerebral arteries were similar to normal controls, but the cerebral vascular resistance, critical pressure and pulsatility index were increased, and cerebral arterial elasticity and cerebral blood flow autoregulation were decreased. Compared with the le-sioned hemisphere of patients with cerebral infarction, the total blood supply and blood flow rate of patients with cerebral arteriosclerosis were higher. Compared with normal subjects, patients with cerebral arteriosclerosis exhibited cognitive disturbances, mainly in short-term memory, attention, abstract capability, and spatial and executive dysfunction. Results showed that cerebral arteriosclerosis does not directly affect the blood supply of a cerebral hemisphere, but affects cognitive function. The increased cerebral vascular resistance and reduced autoregulation of cerebral blood vessels may be important hemodynamic mechanisms of arteriosclerosis-induced cerebral infarction. | Jianbo Yang Changcong Cui Chengbin Wu | 2011 | Neural Regeneration Research2011,6,32: | 0 |