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| 1 | Cerebral ischemia and neuroregeneration显示文摘Cerebral ischemia is one of the leading causes of morbidity and mortality worldwide. Although stroke(a form of cerebral ischemia)-related costs are expected to reach 240.67 billion dollars by 2030, options for treatment against cerebral ischemia/stroke are limited. All therapies except anti-thrombolytics(i.e., tissue plasminogen activator) and hypothermia have failed to reduce neuronal injury, neurological deficits, and mortality rates following cerebral ischemia, which suggests that development of novel therapies again st stroke/cerebral ischemia are urgently needed. Here, we discuss the possible mechanism(s) underlying cerebral ischemia-induced brain injury, as well as current and future novel therapies(i.e., growth factors, nicotinamide adenine dinucleotide, melatonin, resveratrol, protein kinase C isozymes, pifithrin, hypothermia, fatty acids, sympathoplegic drugs, and stem cells) as it relates to cerebral ischemia. | Reggie H.C.Lee Michelle H.H.Lee Celeste Y.C.Wu Alexandre Couto e Silva Harlee E.Possoit Tsung-Han Hsieh Alireza Minagar Hung Wen Lin | 2018 | Neural Regeneration Research2018，13，3： | 30 |
| 2 | Postpartum depression:A systematic review of the genetics involved显示文摘Postpartum depression is one of the most prevalent psychopathologies. Its prevalence is estimated to be between 10% and 15%. Despite its multifactorial etiology, it is known that genetics play an important role in the genesis of this disorder. This paper reviews epidemiological evidence supporting the role of genetics in postpartum depression(PPD). The main objectives of this review are to determine which genes and polymorphisms are associated with PPD and discuss how this association may occur. In addition, this paper explores whether these genes are somehow related to or even the same as those linked to Major Depression(MD). To identify gaps in the current knowledge that require investigation, a systematic review was conducted in the electronic databases Pub Med, LILACS and Sci ELO using the index terms 'postpartum depression' and 'genetics'. Literature searches for articles in peerreviewed journals were made until April 2014. PPD was indexed 56 times with genetics. The inclusion criteria were articles in Portuguese, Spanish or English that were available by institutional means or sent by authors upon request; this search resulted in 20 papers. Genes and polymorphisms traditionally related to MD, which are those involved in the serotonin, catecholamine, brain-derived neurotrophic factor and tryptophan metabolism, have been the most studied, and some have been related to PPD. The results are conflicting and some depend on epigenetics, which makes the data incipient. Further studies are required to determine the genes that are involved in PPD and establish the nature of the relationship between these genes and PPD. | Tiago Castro e Couto Mayra Yara Martins Brancaglion António Alvim-Soares Lafaiete Moreira Frederico Duarte Garcia Rodrigo Nicolato Humberto Corrêa Regina Amélia Lopes P Aguiar Henrique Vitor Leite | 2015 | World Journal of Psychiatry2015，5，1： | 5 |
| 3 | Decoloufization of synthetic dyes by Trametes hirsute in expanded-bed reactors显示文摘 | Couto S R Rosales E Sanroman M A | 2006 | Chemosphcre2006，62，： | 1 |
| 4 | Relationships be-tween the mineralogical and chemical composition of tropical soils and to-pography from hyperspectral remote sensing data显示文摘 | GAL~VAO L S FORMAGGIO A R COUTO E G | 2008 | ISPRS Journal ofPhotogrammetry and Remote Sensing2008，63，2： | 1 |
| 5 | Sequential injection analysis of chloride and nitrate in waters with improved accuracy using potentiometric detection显示文摘 | Santos E Montenegro M C B S M Couto C | 2004 | Talanta2004，63，3： | 1 |
| 6 | Chemical speciation and phase fractionation of N, S and C1 compounds in the atmosphere of Reconcavo, Bahia, Brazil显示文摘 | Campos V P Couto E R Miranda J P | 2013 | Microchemical Journal2013，109，： | 1 |
| 7 | An Investi- gation of Two-Phase Oil/Water Paraffin Deposition 显示文摘 | Couto G H Chen H Dellecase E | 2008 | SPE Production & Operations2008，23，1： | 1 |
| 8 | Increased laccase production by Trametes hirsuta grown on ground orange peelings显示文摘 | Rosales E Couto S R Sanroman M A | 2007 | Enzyme and Microbial Technology2007，40，5： | 1 |
| 9 | Macrophages mediate cardioprotective cel|ular postconditioning in acute myocardial infarction 显示文摘 | de Couto G Liu W Tseliou E | 2015 | JClin Invest2015，，8： | 1 |
| 10 | An improved method for the determination of petroleum hydrocarbons from soil using a simple ultrasonic extraction and fourier transform infrared spectrophotometry显示文摘 | Couto MN Borges JR Guedes P Almeida R Monteiro E Almeida CMR Basto MCP Vaseoncelos MTSD | 2014 | Petroleum Science and Technology2014，32，4： | 1 |
| 11 | Late results concerning feasibility and compliance from a randomized trial of ultrasonographic screening for abdominal aortic aneurysm显示文摘 | Vardulaki KA Walker NM Couto E | 2002 | Br J Surg2002，89，7： | 1 |
| 12 | Folate intake and colorectal cancer risk显示文摘 | Sanjoaquin MA Allen N Couto E | 2005 | Int J Cancer2005，135，11： | 1 |
| 13 | Macrophages mediate cardioprotective cellular posteonditioning in acute myocardial infarction显示文摘 | De Couto G Liu W Tseliou E | 2015 | The Journal of clinical investigation2015，125，8： | 1 |
| 14 | Folate intake and colorectal cancer risk:ameta-analytical approach显示文摘 | Sanjoaquin MA Allen N Couto E | 2005 | Int J Cancer2005，113，5： | 1 |
| 15 | New uses of food waste:application to laccase production by Trametes hirsuta 显示文摘 | E Rosales S Rodriguez Couto A Sanroman | 2004 | Biotechnology Letters2004，24，9： | 1 |
| 16 | Relation-ships between the mineralogical and chemical composi-tion of tropical soils and topography from hyperspectralremote sensing data显示文摘 | Galvao L S Formaggio A R Couto E G | 2008 | ISPRS Journal of Photogramme-try & Remote Sensing2008，63，2： | 1 |
| 17 | Utilisation of grape seeds for laccase production in solid-state fermentors 显示文摘 | Couto S R Lopez E Sanroman M a | 2006 | Journal of Food Engineering2006，74，： | 1 |
| 18 | Human capital and socialcapital in entrepreneurs and managers of small and mediumenterprises 显示文摘 | FEL魱CIO J A COUTO E CAIADO J | 2012 | Journal of Business Economics and Management2012，13，3： | 1 |
| 19 | Detection and identification of grape varieties in must and wine using nuclear and chloro plast microsatellite markers显示文摘 | BALEIRAS COUTO M M EIRAS-DISA J E | | 0，，： | 1 |
| 20 | DOC and DIC in flowpaths of amazonian headwater catchments with hydrologically contrasting soils显示文摘 | Johnson M Lehmann J Couto E | 2006 | Biogeochemistry2006，81，1： | 1 |
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