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| 1 | Direct anterior total hip arthroplasty: Literature review of variations in surgical technique显示文摘The direct anterior approach to the hip has been suggested to have several advantages compared to previously popular approaches through its use of an intra-muscular and intra-nervous interval betweenthe tensor fasciae latae and sartorius muscles. Recent increased interest in tissue-sparing and minimallyinvasive arthroplasty has given rise to a sharp increase in the utilization of direct anterior total hip arthroplasty. A number of variations of the procedure have been described and several authors have published their experiences and feedback to successfully accomplishing this procedure. Additionally, improved understanding of relevant soft tissue constraints and anatomic variants has provided improved margin of safety for patients. The procedure may be performed using speciallydesigned instruments and a fracture table, however many authors have also described equally efficacious performance using a regular table and standard arthroplasty tools. The capacity to utilize fluoroscopy intraoperatively for component positioning is a valuable asset to the approach and can be of particular benefit for surgeons gaining familiarity. Proper management of patient and limb positioning are vital to reducing risk of intra-operative complications. An understanding of its limitations and challenges are also critical to safe employment. This review summarizes the key features of the direct anterior approach for total hip arthroplasty as an aid to improving the understanding of this important and effective method for modern hip replacement surgeons. | Keith P Connolly Atul F Kamath | 2016 | World Journal of Orthopedics2016，7，1： | 33 |
| 2 | Direct anterior total hip arthroplasty:Comparative outcomes and contemporary results显示文摘Direct anterior total hip arthroplasty has become increasingly more popular among arthroplasty surgeons,in large part due to the use of an intramuscular interval and desire to reduce soft tissue damage.Several studies have now been published comparing the anterior intramuscular to other commonly used approaches,and many studies have published complication rates on large series of patients.Review of comparative studies indicates direct anterior hips tend towards shorter hospital stays and high rates of patients discharged to home.Although some studies show evidence of early benefit in functional outcomes,there is no strong evidence that the anterior approach provides any long term functional improvements compared to other approaches.Additionally,evidence to support reduced damage to soft tissue may not translate to certain clinical significance.Rates of intra-operative femur fracture,operative time and blood loss rates are notably higher for those developing familiarity with this approach.However,when surgeons have performed a modest number of procedures,the complication rates tend to markedly decrease in most studies to levels comparable to other approaches.Accuracy of component positioning also favors the anterior approach in some studies.This review summarizes the available literature comparing the direct anterior to other approaches for total hip arthroplasty and provides a comprehensive summary of common complications. | Keith P Connolly Atul F Kamath | 2016 | World Journal of Orthopedics2016，7，2： | 14 |
| 3 | 比较胺碘酮加β受体阻断剂、单用索他洛尔与单用β受体阻断剂预防埋藏式复律除颤器电击的随机试验:OPTIC研究显示文摘Context: Implantable cardioverter defibrillator(ICD) therapy is effective but is associated with high-voltage shocks that are painful. Objective: To determine whether amiodarone plus β -blocker or sotalol are better than β -blocker alone for prevention of ICD shocks. Design, Setting, and Patients: A randomized controlled trial with blinded adjudication of events of 412 patients from 39 outpatient ICD clinical centers located in Canada, Germany, United States, England, Sweden, and Austria, conducted from January 13, 2001, to September 28, 2004. Patients were eligible if they had received an ICD within 21 days for inducible or spontaneously occurring ventricular tachycardia or fibrillation. Intervention: Patients were randomized to treatment for 1 year with amiodarone plus β -blocker, sotalol alone, or β -blocker alone. Main Outcome Measure: Primary outcome was ICD shock for any reason. Results: Shocks occurred in 41 patients(38.5% ) assigned to β -blocker alone, 26(24.3% ) assigned to sotalol, and 12(10.3% ) assigned to amiodarone plus β -blocker. A reduction in the risk of shock was observed with use of either amiodarone plus β -blocker or sotalol vs β -blocker alone(hazard ratio[HR], 0.44; 95% confidence interval[CI], 0.28- 0.68; P< .001). Amiodarone plus β -blocker significantly reduced the risk of shock compared with β -blocker alone(HR, 0.27; 95% CI, 0.14- 0.52; P< .001) and sotalol(HR, 0.43; 95% CI, 0.22- 0.85; P=.02). There was a trend for sotalol to reduce shocks compared with β -blocker alone(HR, 0.61; 95% CI, 0.37- 1.01; P=.055). The rates of study drug discontinuation at 1 year were 18.2% for amiodarone, 23.5% for sotalol, and 5.3% for β -blocker alone. Adverse pulmonary and thyroid events and symptomatic bradycardia were more common among patients randomized to amiodarone. Conclusions: Despite use of advanced ICD technology and treatment with a β -blocker, shocks occur commonly in the first year after ICD implant. Amiodarone plus β -blocker is effective for preventing these shocks and is more effective than sotalol but has an increased risk of drug-related adverse effects. Clinical Trials Registration: ClinicalTrials.gov Identifier: NCT00257959. | Connolly S.J Dorian P Roberts R.S. 黄浙勇 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，5： | 3 |
| 4 | The A'BC for life'programme-teaching basic life support in schools显示文摘 | Connolly M Toner P Connolly D | 2007 | Resuscitation2007，72，2： | 1 |
| 5 | A thermodynamic-basedevaluation of organic chemical accumulation in aquatic organisms显示文摘 | CONNOLLY J P PEDERSON C J | 1988 | Environmental Science and Technology1988，22，1： | 1 |
| 6 | Elastic impedance normalization显示文摘 | Whitcombe D N Connolly P A Reagan R L | 2002 | Geophysics2002，67，1： | 1 |
| 7 | Elastic impedance显示文摘 | Connolly P | 1999 | The Leading Edge1999，18，： | 1 |
| 8 | Anterior cervical plate fixation with the titanium hollow screw plate system显示文摘 | Kostuik JP Connolly P J Esses SI | 1993 | Spine1993，18，： | 1 |
| 9 | Elastic impedance显示文摘 | Connolly P | 1999 | The Leading Edge1999，18，4： | 1 |
| 10 | Notch-l mediates endo thelial cell activation and invasion in psoriasis显示文摘 | Rooney P Connolly M Gao W | 2014 | Exp Dermatol2014，23，2： | 1 |
| 11 | Comparison of beta-blockers, amiodarone plus beta-blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: the OPTIC Study: a randomized trial 显示文摘 | Connolly SJ Dorian P Roberts RS | 2006 | JAMA2006，295，2： | 1 |
| 12 | Elastic impedance显示文摘 | CONNOLLY P | 1999 | The Leading Edge1999，18，： | 1 |
| 13 | The effect of concentration of adsorbing solids on the partition coefficient显示文摘 | O'CONNOR D J CONNOLLY J P | 1980 | Water Research1980，14，10： | 1 |
| 14 | Scoping prediction of re-radiated ground-borne noise and vibration near high speed rail lines with variable soils显示文摘 | CONNOLLY D P KOUROUSSIS G | 2014 | Soil Dynamics and Earthquake Engineering2014，66，： | 1 |
| 15 | Environ- mental and geometric constraints on Indo-Pacific coral reef biodiversity显示文摘 | Bellwood D R Hughes T P Connolly S R | 2005 | Ecol Lett2005，763，： | 1 |
| 16 | Elastic impedance 显示文摘 | Connolly P | 1999 | The Leading Edge1999，18，4： | 1 |
| 17 | Elastic impedance显示文摘 | Connolly P | 1999 | The Leading Edge1999，18，4： | 1 |
| 18 | Comparison of beta- blockers,amiodarone plus beta-blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: the OPTIC Study : a randomized trial显示文摘 | Connolly S J Dorian P Roberts RS | 2006 | JAM A2006，295，2： | 1 |
| 19 | Comparison of beta-blockers,amiodarone plus beta-blockers,or sotalol for prevention of shocks from implantable cardioverter defibrillators:the OPTIC Study:a randomized trial显示文摘 | Dorian P Roberts RS | 2006 | JAMA2006，295，16： | 1 |
| 20 | Septin roles in tumorigenesis显示文摘 | Connolly D Abdesselam I Verdier-Pinard P | 2011 | Biol Chem2011，392，89： | 1 |
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