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217篇 您的检索式:作者名="COMBS E"
    题名 作者 年代 出处 被引量
1Regulation of Wnt/β-catenin signaling by herpesviruses显示文摘The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact with and manipulate this pathway. Successful coexistence with the host requires that herpesviruses establish a lifelong infection that includes periods of latency and reactivation or persistence. Many herpesviruses establish latency in progenitor cells and viral reactivation is linked to host-cell proliferation and differentiation status. Importantly, Wnt/β-catenin is tightly connected to stem/progenitor cell maintenance and differentiation. Numerous studies have linked Wnt/β-catenin signaling to a variety of cancers, emphasizing the importance of Wnt/β-catenin pathways in development, tissue homeostasis and disease. This review details how the alpha-, beta-, and gammaherpesviruses interact and manipulate the Wnt/β-catenin pathway to promote a virus-centric agenda.Kevin J Zwezdaryk Joseph A Combs Cindy A Morris Deborah E Sullivan 2016World Journal of Virology2016,5,4:2
2高羊茅干草部分替代玉米和紫花苜蓿青贮饲料对奶牛消化、泌乳性能的影响显示文摘试验旨在研究高羊茅干草替代玉米或紫花苜蓿青贮对奶牛中性洗涤纤维(NDF)消化率、泌乳性能的影响。选取初产哺乳荷斯坦奶牛(产奶75±35 d)24头,经产荷斯坦奶牛(产奶68±19 d)40头,随机分成4组,共设置32个进料闸门,记录采食量。每组8个进料阀门,以1头牛为1个试验单位,每头牛试验过程中可接触8个进料闸门。试验用高羊茅干草(TF)取代玉米青贮饲料(CS)或紫花苜蓿青贮饲料(AS),试验设计为:33%AS和67%CS(空白组)、60%TF和40%AS(试验1组)、60%TF和40%CS(试验2组)、33%TF和67%CS(试验3组)。试验进行7周,前2周进行预饲。试验结果表明,各组间牛奶产量无显著差异,平均值为40.4 kg·d^(-1)。各组间牛奶中脂肪含量和浓度、蛋白质含量和浓度均无显著差异,平均值为1.58 kg·d^(-1)和3.94%、1.28 kg·d^(-1)和3.15%。与试验1组(22.1 kg·d^(-1))、试验3组(22.7 kg·d^(-1))相比,空白组的干物质摄入量最高,为24.5kg·d^(-1)。各组间总的干物质消化率无显著差异,平均值为66.2%。与试验2组(44.4%)、试验3组(45.3%)相比,空白组的NDF消化率较低,为37.8%,与试验1组(42.4%)相近。各组间奶牛体内NDF消化率(42.3%)与预估的NDF消化率(42.6%)相近。试验结果表明,饲喂高羊茅干草可提高饲料中NDF消化率,部分替代玉米和紫花苜蓿时对产奶量无显著影响,在市场价格较低时,可作为经济实用的奶牛饲料。Bender R W Lopes F Cook D E Combs D K 2016饲料博览2016,0,8:2
3MR imaging of neoplas tie central nervous system lesions: review and recommendations for current practice显示文摘Essig M Anzalone N Combs S E 2012AJNR2012,33,5:1
4Optical and scintillation properties of pure and Ce3+-doped Cs2LiYCl6 and Li3YCl6:Ce3+ crystals显示文摘COMBES C M DORENBOS P VAN EIJK C W E 1999J Lumin1999,82,29:1
5Identifi-cation of microglial signal transduction pathways me-diating a neurotoxic response to amyloidogenic frag-ments of beta-amyloid and prion proteins显示文摘Combs C K Johnson D E?Cannady S B 1999J Neu-rosci1999,19,:1
6Combinatorial rule explosion eliminated by fuzzy rule configuration 显示文摘Combs W E Andrews J E 1998IEEE Transaction on Fuzzy Systems1998,6,1:1
7Anaemia in haemodialysis patients of five European countries:association with morbidity and mortality in the Dialysis Outcomos and Practice Patterns Study(DOPPS)显示文摘Locatelli F Pisoni RL Combe E 2004Nephrol Dial Transplant2004,19,:1
8ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism显示文摘Berg A H Combs T P Scherer P E 2002Trends in Endocrinology and Metabolism2002,13,2:1
9Relationship of fetal maerosomia to maternal post prandial glucose control during pregnaney显示文摘Combs CA Gunderson E Kitzmiller JL 1992Diabetes Care1992,10,:1
10Optical and scintillation properties of Li Ba F3∶Ce crystals显示文摘Combes C M Dorenbos P van Eijk C W E 1997Journal of Luminescence1997,7274,:1
11Effect of selenium and vitamin E dietary deficiencies on chick lymphoid organ development 显示文摘MARSH J A COMBS G F WHITACRE M E 1986Proc Soc Exp Biol Med1986,182,:1
12Comparative evaluation of radiochemotherapy with temozolomide versus stan- dard - of- care postoperative radiation alone in patients with WHO grade Ⅲ astrocytie tumors 显示文摘Stephanie E Combs M N Lutz E 2008Radiother Oncol2008,88,2:1
13Structure and promoter activity of the 5 flanking region of ace-l, the gene encoding acetylcholinesterase of class A in Caenorhabditis elegans 显示文摘Culetto E Combes D Fedon Y 1999Journal of Molecular Biology1999,290,5:1
14Beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes显示文摘McDonald D R Bamberger M E Combs C K 1998J Neurosci1998,18,12:1
15Procalcitonin Kinetics as a Prognostic Marker of Ventilator-associated Pneumonia 显示文摘Luyt C E Guerin V Combes A 2005Am J Respir Crit Care Med2005,171,1:1
16Effect of population size and unbalanced data sets on QTL detec- tion using genome-wide association mapping in barley breeding germplasm 显示文摘WANG H Y SMITH K P COMBS E 2012Theoretical and Applied Ge- netics2012,124,1:1
17Relationship of fetalmacrosom ia to maternal postp randial glucose control during Pregnancy显示文摘Combs CA Gunderson E Kitzmiller JL 1992Diabetes Care1992,10,:1
18Response of advanced bipolar processes to ionizing radiation显示文摘Enlow E W Pease R L Combs W 1991IEEE Trans Nucl Sci1991,49,6:1
19Cryo-SEM and ESEM s new techniques tO investigate phase interactions within reservoir rocks显示文摘Robin M Combes R Rosenberg E 1999SPE 568291999,,:1
20Product performance and consumersatisfaction : A new concept 显示文摘Swan J E Combs L J 1976Journal of Marketing1976,40,2:1
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