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| 1 | Diagnostic delay in oral squamous cell carcinoma: the role of cognitive and psychological variables显示文摘This retrospective study investigated, in two cohorts of subjects living in Southern Italy and awaiting treatment for oral squamous cell carcinoma(OSCC), the variables related to diagnostic delay ascribable to the patient, with particular reference to the cognitive and psychological ones. A total of 156 patients with OSCC(mean age: 62 years, M/F: 2.39 : 1) were recruited at the Universities of Palermo and Naples. Risk factors related to patient delay included: sociodemographic, health-related, cognitive and psychological variables. The analysis was conducted by considering two different delay ranges: dichotomous(f1 month vs..1 month) and polytomous(,1 month, 1–3 months,.3 months) delay. Data were investigated by univariate and multivariate analyses and a P value f0.05 was considered statistically significant. For both delay measurements, the most relevant variables were: ‘Personal experience of cancer'(dichotomous delay: P50.05, odds ratio(OR)50.33, 95% confidence interval(CI)50.11–0.99; polytomous delay: P50.006, Chi-square510.224) and ‘Unawareness'(dichotomous delay: P,0.01, OR54.96, 95% CI52.16–11.37; polytomous delay: P50.087, Chi-square54.77). Also ‘Denial'(P,0.01, OR56.84, 95% CI52.31–20.24) and ‘Knowledge of cancer'(P50.079, Chi-square58.359) were found to be statistically significant both for dichotomous and for polytomous categorization of delay, respectively. The findings of this study indicated that, in the investigated cohorts, the knowledge about cancer issues is strongly linked to the patient delay. Educational interventions on the Mediterranean population are necessary in order to increase the patient awareness and to emphasize his/her key role in early diagnosis of OSCC. | Vera Panzarella Giuseppe Pizzo Francesco Calvino Domenico Compilato Giuseppe Colella Giuseppina Campisi | 2014 | International Journal of Oral Science2014，6，1： | 2 |
| 2 | Microbiota revolution:How gut microbes regulate our lives显示文摘The human intestine is a natural environment ecosystem of a complex of diversified and dynamic microorganisms,determined through a process of competition and natural selection during life.Those intestinal microorganisms called microbiota and are involved in a variety of mechanisms of the organism,they interact with the host and therefore are in contact with the organs of the various systems.However,they play a crucial role in maintaining host homeostasis,also influencing its behaviour.Thus,microorganisms perform a series of biological functions important for human well-being.The host provides the microorganisms with the environment and nutrients,simultaneously drawing many benefits such as their contribution to metabolic,trophic,immunological,and other functions.For these reasons it has been reported that its quantitative and qualitative composition can play a protective or harmful role on the host health.Therefore,a dysbiosis can lead to an association of unfavourable factors which lead to a dysregulation of the physiological processes of homeostasis.Thus,it has previously noted that the gut microbiota can participate in the pathogenesis of autoimmune diseases,chronic intestinal inflammation,diabetes mellitus,obesity and atherosclerosis,neurological disorders(e.g.,neurological diseases,autism,etc.)colorectal cancer,and more. | Marica Colella Ioannis Alexandros Charitos Andrea Ballini Concetta Cafiero Skender Topi Raffaele Palmirotta Luigi Santacroce | 2023 | World Journal of Gastroenterology2023，29，28： | 2 |
| 3 | Deoxycholic acid activates protein kinase C and phospholipase C via increased Ca^2+ entry at plasma membrane显示文摘 | Lau B W Colella M Ruder W C | 2005 | Gastroenterology2005，128，3： | 1 |
| 4 | The piecewise parabolic method (PPM) for gas dynamical simulations显示文摘 | Colella P Woodward PR | 1984 | Journal of Computational Physics1984，54，1： | 1 |
| 5 | Analysis of the Ventilation Systems in the Dartford Tunnels using a Multi- scale Modelling Approach 显示文摘 | COLELLA F REIN G CARVEL R O | 2010 | Tunneling and Underground Space Technology2010，，25： | 1 |
| 6 | Malignant intracerebellar schwannoma显示文摘 | Maiuri F Colella G D Acunzi G | | 0，，1： | 1 |
| 7 | Non-erythropoietic eryth-ropoietin derivatives protect from light-induced and genetic photore-ceptor degeneration显示文摘 | Colella P Iodice C Di Vicino U | 2011 | Hum Mol Genet2011，20，11： | 1 |
| 8 | Matrix refinement equations: and uniquess 显示文摘 | Hell C Colella D | 1996 | Fourier AnalAppl1996，，2： | 1 |
| 9 | Diffusion and adsorption of hydrocarbons from automotive engine exhaust in zeolitic adsorbents显示文摘 | Caputo D Eie M Colella C | 2002 | Studies in Surface Science and Catalysis2002，142，： | 1 |
| 10 | Leptin effect on en- dothelial nitric oxide is mediated through Aket-endothe- lial nitric oxide sythase phosphorylation pathway 显示文摘 | Vecchione C Maffei A Colella S | 2002 | Di- abetes2002，51，1： | 1 |
| 11 | Endoscopy versus microsurgical cyst excision and shunting for treating intracranial arachnoid cysts显示文摘 | Gangemi M Seneca V Colella G et ai | 2011 | J Neurosurg Pediatrics2011，8，2： | 1 |
| 12 | Leptin effect on endothelial nitricoxide is mediated through Akt-endothelial nitricoxidesynthase phosphorylation pathway显示文摘 | Vecchione C Maffei A Colella S | 2002 | Diabetes2002，51，1： | 1 |
| 13 | Is endoscopic third ventriculostomy an internal shunt alone显示文摘 | Gangemi M Maim1 F Colella G | 2007 | Minim Invasive Neurosurg2007，50，1： | 1 |
| 14 | Primary energy savings through thermal storage in district heating networks显示文摘 | Vittorio Verda Francesco Colella | 2011 | Energy2011，，7： | 1 |
| 15 | Dual-site lef ventricular cardiac resynchronization therapy 显示文摘 | Padeletti L Colella A Michelucci A | 2008 | The American journal of cardiology2008，102，12： | 1 |
| 16 | Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovalian cancer 显示文摘 | Zafaroni N Pennati M Colella G et 81 | 2002 | Cell Mol Life Sci2002，59，8： | 1 |
| 17 | Increased cell density decreases eysteine proteinase inhibitor activity and increases invasive ability of two prostate tumor cell lines显示文摘 | COLELLA R GOODWYN E GOPAL P | 2002 | Cancer Letters2002，185，2： | 1 |
| 18 | Solid-state laser synthetic aperture radar显示文摘 | Marcus S Colella B C Green T J | 1994 | Appl Opt1994，33，96： | 1 |
| 19 | Ocular gene therapy: current progress and future prospects 显示文摘 | Colella P Cotugno G Attricchio A | 2009 | Trends Mol Med2009，15，1： | 1 |
| 20 | Matrigel invasion by the prostate cancer cell lines, PC3 and DUI45, and cathepsin L+B aetivity显示文摘 | COLELLA R JACKSON T GOODWYN E | 2004 | Biotcehnic & Histochemistry2004，79，34： | 1 |
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