|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Different risk factors influence peptic ulcer disease development in a Brazilian population显示文摘AIM: To investigate age, sex, histopathology and Helicobacter pylori (H. pylori) status, as risk factors for gastroduodenal disease outcome in Brazilian dyspeptic patients.tients submitted to upper gastroscopy at Hospital das Clinicas of Marilia, antral biopsy specimens were obtained and subjected to histopathology and H. pylori diagnosis. All patients presenting chronic gastritis (CG) and peptic ulcer (PU) disease localized in the stomach, gastric ulcer (GU) and/or duodenal ulcer (DU) were included in the study. Gastric biopsies (n = 668) positive for H. pylori by rapid urease test were investigated for vacuolating cytotoxin A (vacA ) medium (m) region mosaicism by polymerase chain reaction. Logistic regression analysis was performed to verify the association of age, sex, histopathologic alterations, H. pylori diagnosis and vacA m region mosaicism with the incidence of DU, GU and CG in patients. RESULTS: Of 1466 patients submitted to endoscopy, 1060 (72.3%) presented CG [male/female = 506/554; mean age (year) ± SD = 51.2 ± 17.81], 88 (6.0%) presented DU [male/female = 54/34; mean age (year) ± SD = 51.4 ± 17.14], and 75 (5.1%) presented GU [male/female = 54/21; mean age (year) ± SD = 51.3 ± 17.12] and were included in the comparative analysis. Sex and age showed no detectable effect on CG incidence (overall c 2 = 2.1, P = 0.3423). Sex [Odds ratios (OR) = 1.8631, P = 0.0058] but not age (OR = 0.9929, P = 0.2699) was associated with DU and both parameters had a highly significant effect on GU (overall c 2 = 30.5, P < 0.0001). The histopathological results showed a significant contribution of ageing for both atrophy (OR = 1.0297, P < 0.0001) and intestinal metaplasia (OR = 1.0520, P < 0.0001). Presence of H. pylori was significantly associated with decreasing age (OR = 0.9827, P < 0.0001) and with the incidence of DU (OR = 3.6077, P < 0.0001). The prevalence of m1 in DU was statistically significant (OR = 2.3563, P = 0.0018) but not in CG (OR = 2.678, P = 0.0863) and GU (OR = 1.520, P = 0.2863). CONCLUSION: In our population, male gender was a risk factor for PU; ageing for GU, atrophy and metapla-sia; and H. pylori of vacA m1 genotype for DU. | Rodrigo Buzinaro Suzuki Rodrigo Faria Cola Larissa Tranquilino Bardela Cola Camila Garcia Ferrari Fred Ellinger Altino Luiz Therezo Luis Carlos da Silva André Eterovic Márcia Aparecida Sperana | 2012 | World Journal of Gastroenterology2012，18，38： | 8 |
| 2 | of wear resistant high chromium, high carbon cast irons显示文摘 | Maldonado-ruiz S I lopez Mierostruetural evaluation D Velasco A Colas R | 2004 | Material Science and Technology2004，20，3： | 1 |
| 3 | 显示文摘 | Colas B Le Meste M | 1992 | J Food Sci1992，57，3： | 1 |
| 4 | Rapid Differential Diagnosis of Rinderpest and Pest des Petits Ruminants Using an lmmunocapture ELISIA显示文摘 | G libeau A Diallo F Colas | 1994 | Thr Vererinary record1994，134，12： | 1 |
| 5 | Condensation inside and outside smooth and enhanced tubes-a review of recent research 显示文摘 | Cavallini A Censi C Del Cola D | 2003 | International Journal of Refrigeration2003，26，： | 1 |
| 6 | Photoacoustic characterization of carbon nanotube array thermal interfaces显示文摘 | Baratunde A Cola Xu Jun Cheng Changrui | 2007 | J Appl Phys2007，101，05： | 1 |
| 7 | Signal peptideregulated toxicity of a plant ribosome-inactivating protein during cell stress显示文摘 | Marshall R S D′Avila F Di Cola A | | 0，，02： | 1 |
| 8 | Contact mechanics and thermal conductance of carbon nanotube array interfaces显示文摘 | Baratunde A Cola Xu Jun Timothy S Fisher | 2009 | Int J Heat Mass Trans2009，52，： | 1 |
| 9 | Condensation inside and outside smooth and enhanced tubes-a review of recent research显示文摘 | A Cavallinia G Censia D Del Cola | 2003 | International Journal of Refrigeration2003，26，： | 1 |
| 10 | Regional age-related changes in neuronal nitric oxide syn thase (nNOS),messenger RNA levels and activity in SAMP8 brain显示文摘 | Colas D Gharib A Bezin L Morales A Guidon G Cespuglio R | 2006 | BMC Neurosci2006，21，： | 1 |
| 11 | Aging in Heat Treatment Cast Aluminum Alloy显示文摘 | Garcia-Celis A Colas R | 1999 | Heat Treatment1999，27，5： | 1 |
| 12 | Stress Analysis of a 900MW Pressurizer Surge Line Including Stratification Effects显示文摘 | Ensel C Colas A Barthez M | 1995 | Nuclear Engineering and Design1995，153，： | 1 |
| 13 | FLASH is es- sential during early embryogenesis and cooperates with p73 to regu- late histone gene transcription 显示文摘 | De Cola A Bongiorno-Borbone L Bianchi E | 2012 | Oncogene2012，31，6： | 1 |
| 14 | Experimental investigation on condensation heat transfer and pressure drop of new HFC refrigerants (R134a, R125, R32, R410A, R236ea) in a horizontal smooth tube 显示文摘 | Cavallini A Censi G Del Cola D | 2001 | International Journal of Refrigeration2001，24，： | 1 |
| 15 | LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets显示文摘 | Colas R Sassolas A Guichardant M | | 0，，11： | 1 |
| 16 | The burden of comorbidity and the C-reactive protein levels in nonthy- roidal illness syndrome with metabolic syndrome and atherosclerosis-related cardiovascular complications 显示文摘 | MARTOCCHIA A COLA S FRUGONI P | 2010 | Ann N Y Acad Sci2010，1193，： | 1 |
| 17 | Ionic wind generation by a wire-cylinder-plate corona discharge in air at atmospheric显示文摘 | Colas D F Ferret A Pai D Z | 2010 | Journal of Applied Physics Pressure2010，30，6： | 1 |
| 18 | Regional age-related changes in neuronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain 显示文摘 | Colas D Gharib A Bezin L | 2006 | BMC Neurosci2006，21，1： | 1 |
| 19 | FFr - based BP deco- ding of general LDPC codes over abelian groups, communica- tions显示文摘 | GOUPIL A COLAS M GELIY G | 2007 | IEEE Transactions on Communications2007，55，4： | 1 |
| 20 | Stress Analysis of a 900MW Pressurizer Surge Line Including Stratification Effects显示文摘 | Ensel C Colas A Barthez M | 1995 | Nuclear Engineering and Design1995，153，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员