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| 1 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 2 | Maturation in vitro of human oocytes from unstimulatedcycles : selection of the optimal day for ovum retrieval based on follicular size 显示文摘 | Cobo AC Requena A Neuspiller F | 1999 | Hum Reprod1999，14，7： | 1 |
| 3 | Microperforated insertion units: An alternative strategy to design microperforated panels显示文摘 | Jaime Pfretzschner Pedro Cobo Francisco Simón María Cuesta Alejandro Fernández | 2005 | Applied Acoustics2005，，1： | 1 |
| 4 | Chia seeds: microstructure, mucilage extraction and hydration显示文摘 | Munoz LA Cobos A Diaz O Aguilera JM | 2012 | J Food Eng2012，108，1： | 1 |
| 5 | Thrombectomy within 8 hours after symptom onset in ischemic stroke显示文摘 | Jovin TG Chamorro A Cobo E | 2015 | N Engl J Med2015，372，： | 1 |
| 6 | The cylindrical titanium mesh cage for treatment of a long hone se~nental defect: description of a new technique and report of two cases显示文摘 | Cobos JA lJndsey RW Gug~a Z | 2000 | J Orthop Trauma2000，14，1： | 1 |
| 7 | Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitri- fied by the cryotop method显示文摘 | Cobo A Kuwayama M Perez S | 2008 | Fertil Steril2008，89，6： | 1 |
| 8 | Treatment with amniopatch of premature rupture of membranes after first-trimester chorionic villus sampling显示文摘 | Cobo T Borrell A Fortuny A | | 0，，11： | 1 |
| 9 | Single phase power factor correction: a survey显示文摘 | Garcia O Cobos J A Prieto R | 2003 | IEEE Transactions on Power Electronics2003，18，3： | 1 |
| 10 | Embryonic stem ceil bank: a work proposal显示文摘 | Nieto A Cobo F Barroso-Deljesus A | 2006 | Stem Cell Rev2006，2，2： | 1 |
| 11 | Maturation in vitro of human oocytes from unstimulated cycles:selection of the optimal day of ovum retrieval based on follicular size显示文摘 | Cobo AC Requene A Neuspiller F | 1999 | Hum Reprod1999，14，7： | 1 |
| 12 | Lactic Acid Production and Rheologicalproperties of Yogurt Made from Milk Acidified with Carbon Dioxide显示文摘 | CALVO M M MONTILLA A COBOS A | 1999 | J Sci Food Agric1999，79，： | 1 |
| 13 | Synthesis of higher alcohols with cobalt and copper based modelcatalysts: effect of the alkaline metals显示文摘 | Aquino A D Cobo A J G | 2001 | Catal Today2001，65，： | 1 |
| 14 | Several questions about electrochemical rehabilitation methods for reinforced concrete structures 显示文摘 | MIRANDA J M GONZ/LEZ J A COBO A | 2006 | Corro- sion Science2006，48，8： | 1 |
| 15 | Use of cryobanked oocytes in an ovum donation program: a prospective, ran- domized, controlled clinical trial editorial comment 显示文摘 | Cobo A Meseguer M Remohi J | 2010 | Obstetrical & Gynecological Survey2010，65，12： | 1 |
| 16 | Extraction of nickel f rom ammoniacal/ ammonium carbonate solutions using acorga M5640 in iberfluid 显示文摘 | Alguacil F J Cobo A | 1998 | Hydrometallurgy1998，50，： | 1 |
| 17 | Corrosion of Chro rnium Plated Rotor in Drilling Fluid 显示文摘 | Cobo E O Suarez Baldo R A Bessone J B | 1999 | Surface and Coatings Technology1999，122，3： | 1 |
| 18 | 显示文摘 | Gonzalez J A Cobo A Gonzalez M N | 2001 | Corros Sci2001，43，： | 1 |
| 19 | Several question about electrochemical rehabilitation methods for reinforced concrete structures显示文摘 | MIRANDA J M GONZGáLEZ J A COBO A | 2006 | Corrosion Science2006，48，8： | 1 |
| 20 | A biblio- metric study about the research based on hybridating the fuzzy logic field and the other computational inteUigent techniques: A visual approach显示文摘 | L6pez-Herrera A G Cobo M J Herrera-Viedma E | 2010 | International Journal of Hybrid Intelligent Systems2010，7，1： | 1 |
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