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| 1 | 基于IMRT时代的第八版AJCC/UICC鼻咽癌临床分期建议显示文摘目的准确的分期系统对癌症的治疗至关重要。随着癌症分期和治疗方法的演变,需要不断评价分期的适用性和改进性。方法基于第7版AJCC/UICC分期回顾性分析香港和中国大陆2个肿瘤中心收治的1609例接受调强放射治疗的首诊无转移鼻咽癌患者临床资料,所有患者治疗前均行核磁共振分期评估。结果无其他T3、T4期解剖结构受侵患者中,伴有咀嚼肌间隙(翼内肌和/或翼外肌)侵犯、椎前肌侵犯及咽旁间隙侵犯的三组患者之间0s相近。伴广泛软组织(上述侵犯结构以外的软组织)受侵患者OS与伴有颅内侵犯或颅神经侵犯相似。仅2%患者锁骨上窝以上淋巴结转移者直径〉6cm,其0s率与下颈淋巴结转移者类似。用下颈(环状软骨尾侧缘水平以下)代替锁骨上窝并不影响N分期之间的风险差异性。采用推荐的T、N分期,T。N。、T。N,期0s相近。结论经AJCC/UICC分期筹备委员会审阅后,建议第8版分期应将翼内肌/翼外肌从T。降到T:期,增加椎前肌为L期,用下颈取代锁骨上窝,将淋巴结最大直径〉6cm合并归为N,期,将T。、N,期统一归为Ⅳ。期。这些改变不仅使得相邻分期间风险差异性更好,而且使得临床实践性与全球适用性之间达到最佳平衡。 | 潘建基 Wai Tong Ng 宗井凤 Lucy L.K.Chan Brian O' Sullivan 林少俊 Henry C.K.Sze 陈韵彬 Horace C.W.Choi 郭巧娟 Wai Kuen Kan 肖友平 Xu Wei Quynh Thu Le Christine M.Glastonbury A.Dimtrios Colevas Randal S.Weber Jatin P.Shah Anne W.M.Lee | 2016 | 中华放射肿瘤学杂志2016,25,3: | 65 |
| 2 | 我国物流企业全要素生产效率分析显示文摘为分析我国物流企业生产效率的发展情况,本文以我国8家上市物流企业为例,利用DEA Malmqulst生产效率变化指数对它们在2001-2006年的全要素生产效率进行分析。通过分析发现,我国物流企业的生产效率发展趋势较好,呈上升状态,但上升程度并不明显,其中技术效率和技术有所下滑,而规模效率则有所上升。同时结合了企业组织形式、资源配置及发展战略等内部因素和国内外经济发展环境、国家产业发展政策与法规等外部因素对各个企业和它们的整体生产效率发展过程进行了分析和说明,提出了解决我国物流企业生产效率偏低的途径,为政府决策者和物流企业管理者提供了科学决策的依据。 | 邓学平 王旭 Ada Suk Fung Ng 林云 | 2008 | 系统工程2008,26,6: | 41 |
| 3 | 我国物流企业生产效率与规模效率显示文摘首先利用DEA CCR/BCC模型对我国在沪深港证券市场上市的55家物流企业的生产效率和规模效率进行实证比较分析,然后通过相关性分析及多项回归分析研究了规模效率及固定资产规模与生产效率的关系.结果表明:1)大型物流企业相对中小型物流企业而言并不具备显著的效率优势.2)我国物流企业不存在显著的规模效率差异,不应盲目追求资产规模的扩张和重组.3)我国物流企业的纯技术效率大于规模效率对生产效率的影响,物流企业的技术改进比规模扩张更具重要性.4)物流企业生产成本是影响企业生产效率的主要因素,而资产规模和职工工资对生产效率没有显著影响. | 邓学平 王旭 Ada Suk Fung Ng | 2009 | 系统工程理论与实践2009,29,4: | 31 |
| 4 | Epinephrine injection therapy versus a combination of epinepnrine injection and endoscopic hemoclip in the treatment of bleeding ulcers显示文摘AIM: To assess the efficacy of hemoclip application in combination with epinephrine injection in the treatment of bleeding peptic ulcers and to compare the clinical outcomes between patients treated with such a combination therapy and those treated with epinephrine injection alone.METHODS: A total of 293 patients (211 males, 82females) underwent endoscopic therapy for bleeding peptic ulcers. Of these, 202 patients (152 males, 50females) received epinephrine injection therapy while 91patients (59 males, 32 females) received combination therapy. The choice of endoscopic therapy was made by the endoscopist. Hemostatic rates, rebleeding rates, need for emergency surgery and 30-d mortality were the outcome measures studied.RESULTS: Patients who received combination therapy were significantly older (mean age 66±16 years, range24-90 years) and more suffered from chronic renal failure compared to those who received epinephrine injection therapy alone (mean age 61±17 years, range 21-89 years).Failure to achieve permanent hemostasis was 4% in the group who received epinephrine injection alone and 11%in the group who received combination therapy. When the differences in age and renal function between the two treatment groups were taken into account by multivariate analysis, the rates of initial hemostasis,rebleeding rates, need for surgery and 30-d mortality for both treatment options were not significantly different.CONCLUSION: Combination therapy of epinephrine injection with endoscopic hemoclip application is an effective method of achieving hemostasis in bleeding peptic ulcer diseases. However, superiority of combination therapy over epinephrine injection alone, could not be demonstrated. | Tju-Siang Chua Kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Jessica Yi-Lyn Tan Tiing-Leong Ang | 2005 | World Journal of Gastroenterology2005,11,7: | 27 |
| 5 | 【特刊综述】肥胖男性低睾酮的发生机制、发病率及其处理显示文摘随着亚洲现代化和城市化的日益进展,肥胖流行病的未来焦点多在亚洲地区。肥胖男性常会出现低睾酮水平,但他们并不一定有可识别的下丘脑.垂体.睾丸轴(HPT)病理变化。中度肥胖主要降低总睾酮水平,这是由胰岛素抵抗相关的性激素结合球蛋白减少所致。比较严重的肥胖与游离睾酮水平降低有关,这是由下丘脑-垂体-睾丸轴的抑制所致。低睾酮本身可导致肥胖的高风险增加,产生一个恶性循环的代谢综合征。肥胖相关的低睾酮血症是一个功能状态,而非恒定状态。这种状态是可以被逆转的,但这需要持续的减肥。虽然睾酮治疗可以引起中度的脂肪减少,但肥胖本身,在没有雄激素缺乏症状的情况下,不是既定的睾酮治疗的适应症。睾酮治疗可能会导致未经治疗的睡眠呼吸暂停恶化,损害生育能力等。睾酮治疗是否增加饮食或者运动诱导的体重降低需要在充分设计的随机对照临床试验中评估。 | Mark Ng Tang Fui | 2014 | Asian Journal of Andrology2014,16,2: | 28 |
| 6 | 基于扎根理论的高校“水课”教育改革研究显示文摘高校中普遍存在的'水课'现象引起了社会各界的广泛关注。'水课'的存在导致学生无法从教学内容中有效地学到专业知识,浪费他们的时间与精力,同时也意味着学校教学资源的浪费。尽管'水课'现象已经引起了人们的关注,但是目前教育领域的学者却极少关注这种现象。文章使用扎根理论的方法来研究'水课'现象,试图探索出'水课'存在的导因,并据此为我国的高校教育改革提出有科学依据的建议。研究发现,大学生一般会将具有重复性内容的课程、任课教师授课不专业、考核方式过于简单的课程视为'水课'。鉴于此,在深化教育改革过程中,需要在树立课程考核方式,注重提升教师专业水平,重视学生意见等方面深挖完善举措。 | Jhony Choon Yeong Ng 陈红雪 宋凯文 谭清美 夏后学 | 2017 | 高教学刊2017,3,22: | 27 |
| 7 | 利他主义与利他行为:三个年龄群体的扎根理论研究显示文摘已有文献出现了冠以利他行为之名的助人行为研究以及假定利他主义和利他行为的可替换性的混乱局面。鉴于此,采用经典扎根理论的方法,针对高中生、大学生、职场人士这三个年龄群体,在中国的情境下,重新探讨利他主义的本质以及利他主义和利他行为之间的影响机制。研究发现,受访者都具有一定高水平的利他主义,但意外的是,利他主义似乎不影响利他行为的产生。受访者在决定是否助人时,主要考虑的是自己是否有能力助人,以及他们的核心利益是否会被触犯。西方文献所主张的个体助人行为主要受其同情心及行为前成本效益分析影响的观点并未得到支持。本研究不仅颠覆了许多西方学者的观点,而且增添了中国情境的理论观点。 | Jhony Choon Yeong Ng 郑佳 贾良定 谭清美 | 2018 | 中国青年研究2018,,7: | 24 |
| 8 | 臭氧对活性污泥特性影响研究显示文摘探讨了臭氧对于污水生物处理中活性污泥特性的影响。结果显示 ,随着臭氧化的进行 ,促进了活性污泥生物量的减少 ,并有一定量的生物污泥被无机化 ,并且污泥的活性和存活性降低了。其中臭氧投加量低于 0 .1gO3 /gSS时污泥活性即大幅下降 ,而后污泥浓度才随着臭氧量的增加而显著降低。 | 金瑞洪 NG Wun Jern | 2004 | 环境污染治理技术与设备2004,5,9: | 22 |
| 9 | 13181例疑似生殖道支原体感染患者支原体分布及耐药性分析显示文摘近年来生殖道支原体感染的发病率位居全国监测的8种性传播疾病的首位[1]。生殖道支原体常引起非淋球菌性尿道炎,女性宫颈炎、盆腔炎,男性前列腺炎、附睾炎,以及不孕不育等多种疾病。随着抗菌药物的广泛使用,支原体分离株的耐药性也逐渐上升。早前研究发现,男性和女性患者感染的支原体类型可能存在差异,但其临床分布及菌株耐药性的差异则较少见报道。本研究对2014年1至12月宁波大学医学院附属医院13181例疑似生殖道支原体感染患者送检样本的培养及药敏试验结果进行汇总和分析,现将结果报道如下。 | 周琼艳 赵敬军 许素玲 Karina S. Y. Ng How Tseung 郑琳 吕婉飞 汪丽 何姗娜 | 2016 | 中华临床感染病杂志2016,9,2: | 23 |
| 10 | 一群去专业化的人——斜杠青年的事业发展研究显示文摘'斜杠青年'的概念在2016年初被引入中国,并影响了数十万年轻人从事多重职业。然而随着现代社会的发展,各行各业的分工越来越细化,职业专业化程度越来越高。在这种专业化的背景下,斜杠青年这种去专业化的职业模式为何能迅速发展的问题亟待研究。本文采用扎根理论的方法 ,对不同地区、不同年龄段的38位工作者进行深入访谈,对斜杠青年这一群体的动因、特征、发展进行探索性研究。研究发现斜杠青年渴望实现自身价值,渴望多姿多彩的生活,并且具备强项是所在专业的边缘技能、技能精进是工作的主要目标两大特征,未来事业发展方向是以技能创业。本文认为,斜杠青年这类去专业化的人群,在企业中不是核心人员,但不可缺少,因此希望日后管理研究能够重视斜杠青年,并且寻求对这类人群的管理方法。 | Jhony Choon Yeong Ng 邵丹慧 贾良定 谭清美 | 2018 | 中国人力资源开发2018,35,6: | 23 |
| 11 | 澳大利亚精神卫生主流服务模式介绍显示文摘墨尔本大学ST Vincent's精神卫生部承担着西太平洋地区国家的精神卫生服务人员的培训,中国也曾多次派出专业人员接受过社区精神卫生服务的训练。由于培训时间的限制,有些学员对一些问题尚有不清楚之处,因此,本文试图对澳大利亚维多利亚州的主流精神卫生服务模式做一介绍,以其惠及国内更多的精神卫生服务人员。 | 刘铁桥 马弘 Chee Ng | 2007 | 国际精神病学杂志2007,34,1: | 20 |
| 12 | Glioblastoma stem cells resistant to temozolomide-induced autophagy显示文摘背景最近的研究在大脑肿瘤与原始神经祖先房间和开始肿瘤的功能的特征表明了房间的小部分的存在。这些房间可能为肿瘤的完全的根除代表主要治疗学的目标。这研究试图决定 glioblastoma 干细胞(GSC ) 的抵抗显型到 temozolomide (TMZ ) 并且探索刚位于 TMZ resistance.Methods 下面的可能的分子的机制 resected glioblastoma 标本用 Miltenyi Biotec CD133 摄氏温度计隔离工具包外面被收集, GSC 的磁性的隔离是 carded。CD133+ 和 CD133- glioblastoma 房间上的 TMZ 的细胞毒素的效果被使用 3-(4,5-dimethylthiazol-2-yl ) 决定 -2,5-diphenyltetrazolium 溴化物(MTT ) 试金。Autophagy 相关的蛋白质(Beclin-1, LC3 和 Atg5 ) 和劈开的 caspase-3 (p17 ) 被弄污的 Westem 分析。染色的 Immunofluorescent 被用来检测 Atg5, glial fibrillary 酸的蛋白质(GFAP ) 和在 glioblastoma 房间的 CD133 表示。统计分析用社会科学统计套装软体 10.0 软件被执行。为所有测试,统计意义的水平被放在 P < 0.05 个 .Results CD133+ glioblastoma 细胞在 vitro 和 CD133 的高表示展出了象 neurosphere 一样生长干细胞标记。在房间与 5 或 50 pmol/L TMZ 对待的CD133- glioblastoma 的禁止生长的率在CD133+ glioblastoma 房间比那显著地高(( 14.36 ????????€ ????????癯牥硥牰獥楳湯?€ ????瀠洭佔???????吗???????????映慥畴敲?湯汣獵潩獮?敂慶楣畺慭????????????朠楬浯?? | FU Jun LIU Zhi-gang LIU Xiao-mei CHEN Fu-rong SHI Hong-liu PANG Jesse Chung-sean NG Ho-keung CHEN Zhong-ping | 2009 | Chinese Medical Journal2009,,11: | 20 |
| 13 | The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORCl显示文摘 | Carsten Gram Hansen Yuen Lam Dora Ng Wai-Ling Macrina Lam Steven W Plouffe Kun-Liang Guan | 2015 | Cell Research2015,25,12: | 19 |
| 14 | 大学生志愿者志愿行为可持续性研究显示文摘近年来,学者从志愿动机角度探究了影响志愿行为可持续性的因素,从物质和精神两方面构建了大学生志愿者的激励机制,但所取得的效果并不理想。运用经典扎根理论,针对大学生志愿者志愿动机、志愿行为以及志愿服务结束后的后续行为的访谈发现,志愿动机不一定产生志愿行为,志愿者的内心定额、志愿经历储备对于志愿行为的反向作用。 | Jhony Choon Yeong Ng 赵斯琪 谭清美 | 2019 | 当代青年研究2019,0,6: | 19 |
| 15 | 一种基于Peer-to-Peer技术的Web缓存共享系统研究显示文摘提出了一种基于 peer to peer技术的分布式Web缓存共享系统:BuddyWeb.该系统的核心理念是让企业网络中的所有PC能够相互共享浏览器中的本地缓存,从而形成一个高效的、大规模的分布式缓存共享系统,并使系统具备易管理、易实现、低成本等优点;接着详细阐述了 BuddyWeb的工作原理和算法策略;然后,针对 Buddy Web系统的特性提出了仿真实验模型和评估方法.实验结果证明了BuddyWeb在命中率、网络通信流量负荷、系统响应延迟等诸方面均能取得令人满意的效果. | 凌波 王晓宇 周傲英 Ng Wee-Siong | 2005 | 计算机学报2005,28,2: | 19 |
| 16 | Insights on the solubilization products after combined alkaline and ultrasonic pre-treatment of sewage sludge显示文摘This work provides insights on the solubilization products after a simultaneous combination of alkaline and ultrasonic(ALK + ULS) pre-treatment of sewage sludge.Soluble chemical oxygen demand(SCOD) increased from 1200 to 11,000 mg/L after such treatment. Organics with molecular weight around 5.6 k Da were solubilized because of the synergistic effect of ultrasound and alkali. Organics with molecular weight larger than300 k Da increased from 7.8% to 60%, 16% and 42.3% after ULS, ALK and ALK + ULS treatment, respectively. Excitation emission matrix fluorescence spectroscopy analysis identified soluble microbial product-like and humic acid-like matters as the main solubilization products. Sludge anaerobic biodegradability was significantly enhanced with the simultaneous application of ALK + ULS pre-treatment. ALK + ULS pre-treatment resulted in 37.8% biodegradability increase compared to the untreated sludge. This value was higher compared to the biodegradability increase induced by individual ALK pre-treatment(5.7%) or individual ULS pre-treatment(20.7%) under the same conditions applied. | Xinbo Tian Chong Wang Antoine Prandota Trzcinski Leonard Lin Wun Jern Ng | 2015 | Journal of Environmental Sciences2015,27,3: | 19 |
| 17 | Genome Alignment Spanning Major Poaceae Lineages Reveals Heterogeneous Evolutionary Rates and Alters Inferred Dates for KeyEvolutionary Events显示文摘 | Xiyin Wa ng Jingpeng Wang Dianchuan Jin Hui Guo Tae-Ho Lee Tao Liu Andrew H. Paterson | 2015 | Molecular Plant2015,8,6: | 18 |
| 18 | Structure and sequence analysis of influenza A virus nucleoprotein显示文摘Influenza A virus nucleoprotein (NP) forms homo-oligomers and multiple copies of NP wrap around genomic RNA, along with a trimeric polymerase making up ribonucleoprotein (RNP) complex. Sequence comparison of more than 2500 influenza A NP showed that this protein contains 30.1 % of polymorphic residues. NP is composed of a head and a body domain and a tail loop/ linker region. The head domain is more conserved than the body domain, as revealed from the structure-based sequence alignment. NP oligomerization is mediated by the insertion of the non-polymorphic and structurally conserved tail loop of one NP molecule to a groove of another NP. The different form of NP oligomers is due to the flexibility of the polymorphic linkers that join the tail loop to the rest of the protein. The RNA binding property of NP is known to involve the protruding element and the flexible basic loop between the head and body domains, both having high degree of primary sequence conservation. To bind RNA, NP may first capture the RNA by the flexible basic loop and then the RNA is clamped by the protruding element. | NG Andy Ka-Leung SHAW Pang-Chui | 2009 | Science China(Life Sciences)2009,52,5: | 18 |
| 19 | Nitrous oxide emission by denitrifying phosphorus removal culture using polyhydroxyalkanoates as carbon source显示文摘Nitrous oxide(N2O) emission has been reported to be enhanced during denitrification when internally-stored compounds are used as carbon sources.However,negligible N2O emissions have been detected in the few studies where polyhydroxyalkanoates(PHA) were specifically used.This study investigated and compared the potential enhancement of N2O production,based on utilization of an internally-stored polymer and external carbon(acetate) by a denitrifying phosphorus removal culture.Results indicated that at relatively low chemical oxygen demand-to-nitrogen(COD/N) ratios,more nitrite was reduced to N2O in the presence of an external carbon source as compared to an internal carbon source(PHA).At relatively higher COD/N ratios,similar N2O reduction rates were obtained in all cases regardless of the type of carbon source available.N2O reduction rates were,however,generally higher in the presence of an internal carbon source.Results from the study imply that when the presence of an external carbon source is not sufficient to support denitrification,it is likely competitively utilized by different metabolic pathways of denitrifying polyphosphate accumulating organisms(DPAOs) and other ordinary denitrifiers.This study also reveals that the consumption of PHA is potentially the rate-limiting step for N2O reduction during denitrification. | Yan Zhou Melvin Lim Soekendro Harjono Wun Jern Ng | 2012 | Journal of Environmental Sciences2012,24,9: | 17 |
| 20 | Reduced Macular Vascular Density in Myopic Eyes显示文摘 | Hua Fan Hao-Yu Chen Hong-Jie Ma Zheng Chang Hai-Quan Yin Danny Siu-Chun Ng Carol Y Cheung Shan Hu Xiang Xiang Shi-Bo Tang Shuang-Nong Li | 2017 | Chinese Medical Journal2017,,4: | 17 |