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| 1 | Long-term anodal block stimulation at sacral anterior roots promoted recovery of neurogenic bladder function in a rabbit model of complete spinal cord injury显示文摘A complete spinal cord injury model was established in experimental rabbits using the spinal cord clip compression method.Urodynamic examination was performed 2 weeks later to determine neurogenic bladder status.The rabbits were treated with anodal block stimulation at sacral anterior roots for 4 weeks.Electrical stimulation of sacral anterior roots improved urodynamic parameters of neurogenic bladder in rabbit models of complete spinal cord injury,effectively promoted urinary function,and relieved urinary retention.Immunohistochemistry results showed that a balance was achieved among expression of muscarinic receptor subunits M2,M3,ATP-gated ion channel P2X3 receptors,and β2-adrenergic receptor,and nerve growth factor expression decreased.These results suggested that long-term sacral anterior root stimulation of anodal block could be used to treat neurogenic bladder in a rabbit model of complete spinal cord injury. | Xiaoran Wang Qi Gao Xiaoyu Yang Weihua Wang Xinquan Gu Guifeng Liu Peng Yan Ge Gao Xin Yu Yongjie Wang Jihu Lian Chaoling Shi Yao Wang Li Fan | 2012 | Neural Regeneration Research2012，7，5： | 6 |
| 2 | Microstructure of Ba_(0.615)Sr_(0.35)Mg_(0.035)TiO_3 dielectric ceramics via X-ray spectrum analysis显示文摘The compound Ba0.615Sr0.35Mg0.035TiO3 was analyzed by the X-ray dispersed spectroscopy analyzer (SEM-EDAX) with the spec-trum image method, a powerful tool for chemical phase identification. The method was first time applied on a ceramic material to collect spectrum image and was progressed to identify the Mg-enriched component with fine scale pocket shown in matrix. This result, together with the stoichiometry result obtained from spot mode spectrum analysis, strongly confirmed the microstructure and properties of dielectric materials. | QI Wen XUE Tao LI Xuan FANG DongYu LI ChaoLing YAO Pei | 2012 | Chinese Science Bulletin2012，57，34： | 1 |
| 3 | Hydrolysis enhancing mechanisms of Mg-based alloys/hydrides from perspectives:Electrochemical corrosion,active sites,mass transfer,and kinetics显示文摘Hydrogen energy is considered to be an ideal new energy carrier in the 21st century due to its clean,environmentally friendly,renewable characteristics and high energy density.The generation of hydrogen by hydrolysis of Mg-based alloys/hydrides has attracted extensive attention attributed to the high hydrogen yield,environmentally-benign by-products,high crust abundance,and well-developed industrial production of Mg.However,in the hydrolysis process of Mg or MgH_(2)to generate hydrogen,the formed Mg(OH)_(2)passivation layer attaches to the surface of the active materials to prevent the reaction from continuing.To improve the hydrolysis performance,a series of methods have been put forward.In this paper,focusing on the mechanisms of hydrogen generation by hydrolysis of Mg-based alloys/hydrides,we summarize the recent research progress from four different perspectives:electrochemical corrosion promotion by constructing galvanic cells,active sites increment by refining the particles,mass transfer enhancement by breaking Mg(OH)_(2)and corresponding kinetic improvement. | Chaoling Wu Qin Huang Bingshou Gong Ji Zhou Guanghui Xia Fangnan He Yao Wang Yigang Yan Yungui Chen | 2023 | Journal of Materials Science & Technology2023，，32： | 0 |
| 4 | Promoted hydrolysis performances and mechanism of Si-NaBH4-AlCl_(3) in deionized water显示文摘Si-based hydrolysis material system can be used in mobile/portable hydrogen source applications connected to fuel cells but is limited by alkaline solutions.In the present research,we reported an acid/alkaline free hydrolysis systemcombining siliconwith NaBH4.Sampleswith different ratios between Si and NaBH4 are prepared via high energy ball milling and hydrolyzed in deionized water at different temperatures.Synergetic effect between silicon and NaBH4was found in the hydrolysis process.2Si-NaBH4 sample displays the best hydrolysis performances with the hydrogen yield of 1594 ml·g^(−1) in deionized water at 70℃.Thereafter,AlCl3 is added into the 2Si-NaBH4 sample to further improve its comprehensive properties.The effect of AlCl3 content and promotion mechanism of the reaction are explored.2Si-NaBH4-5 wt% AlCl3 sample shows a significant improvement with a high hydrogen yield of 1689 ml·g^(−1) in deionized water at 70℃ and a corresponding conversion rate of 95.8%,indicating that the Si-NaBH4-AlCl3 composite is promising to be a hydrogen source in applications of mobile/portable fuelcell-powered facilities. | Zhao Feng Chaoling Wu Shuang Zhong Yungui Chen Hui Chen Yao Wang | 2020 | Chinese Journal of Chemical Engineering2020，28，12： | 0 |
| 5 | Prognostic prediction and expression validation of NSD3 in pan-cancer analyses显示文摘Background:Nuclear receptor binding SET domain protein-3(NSD3)is a histone lysine methyltransferase and a crucial regulator of carcinogenesis in several cancers.We aimed to investigate the prognostic value and potential function of NSD3 in 33 types of human cancer.Methods:The data were obtained from The Cancer Genome Atlas.Kaplan-Meier analysis,CIBERSORT,gene set enrichment analysis,and gene set variation analysis were performed.The expression of NSD3 was measured using quantitative real-time polymerase chain reaction and western blot.Results:The expression of NSD3 was altered in pan-cancer samples.Patients with higher levels of NDS3 generally had shorter overall survival and disease-specific survival.Levels of NSD3 were positively correlated with DNA copy number variation(CNV)in pan-cancer.NSD3 expression was also associated with tumor mutation burden and microsatellite instability.The levels of immune-cell infiltration differed significantly between high and low NSD3 expression.NSD3 negatively correlated with levels of CD8+T cells.Functional enrichment analysis showed that while NSD3 expression was positively associated with several immune cell-related and histone methylation-related pathways,it was negatively correlated with cell metabolism-related,drug transport-related,and drug metabolismrelated pathways.NSD3 levels in the cell lines tested were significantly different.In U251 and NCI-H23 cells,silencing NSD3 inhibited cell proliferation and promoted apoptosis.Conclusions:NSD3 expression was changed in pan-cancer samples that was also verified in cell lines.NSD3 was associated with CNV and immune-cell infiltration.A poor prognosis was predicted in patients with high expression of NSD3.NSD3 might hence be a potential marker for predicting tumor prognosis. | SHA LI YAQIONG LIU CHAOLING YAO ANJI XU XIAOLING ZENG YUXIN GE XIAOWU SHENG HAILIN ZHANG XIAO ZHOU YING LONG | 2023 | BIOCELL2023，47，5： | 0 |
| 6 | Hydrogen absorption-desorption cycle decay mechanism of palladium nanoparticle decorated nitrogen doped graphene显示文摘As a hydrogen storage material,palladium nanoparticle decorated nitrogen doped graphene(Pd/N-r GO)has drawn much attention owing to its high absorption capacity at moderate conditions.However,its hydrogen absorption-desorption cycle performance,which is essential for their practical application,has been rarely studied.In this paper,a simple and convenient high temperature thermal reduction method was used to synthesize nitrogen-doped graphene decorated with Pd nanoparticles(Pd/N-r GO).Taken it as a representative,the hydrogen absorption-desorption cycle performance of Pd/N-r GO was investigated.The results showed that after three cycles the hydrogen storage capacity dropped from 2.9 wt%to 0.8 wt%at 25℃and 4 MPa pressure.It was found that the palladium nanoparticles shed from Pd/N-RGO sheet after cycle performance test,and then agglomerated.These phenomena will weaken the hydrogen spillover effect,leading to the decrease of hydrogen storage capacity.Meanwhile,decreased defects reduce the hydrogen absorption sites,which will thus deteriorate the hydrogen storage capacity. | Jiao Li Chaonan Jin Ruijun Qian Chaoling Wu Yao Wang Yigang Yan Yungui Chen | 2021 | Progress in Natural Science:Materials International2021，31，4： | 0 |
| 7 | GST family genes in jujube actively respond to phytoplasma infection显示文摘Jujube witches’broom(JWB)caused by phytoplasma has a severely negative effect on multiple metabolisms in jujube.The GST gene family in plants participates in the regulation of a variety of biotic and abiotic stresses.This study aims to identify and reveal the changes in the jujube GST gene family in response to phytoplasma infection.Here,70 ZjGSTs were identified in the jujube genome and divided into 8 classes.Among them,the Tau-class,including 44 genes,was the largest.Phylogenetic analysis indicated that Tau-class genes were highly conserved among species,such as Arabidopsis,cotton,chickpea,and rice.Through chromosome location analysis,37.1%of genes were clustered,and 8 of 9 gene clusters were composed of Tau class members.Through RT-PCR,qRT-PCR and enzyme activity detection,the results showed that the expression of half(20/40)of the tested ZjGSTs was inhibited by phytoplasma infection in field and tissue culture conditions,and GST activity was also significantly reduced.In the resistant and susceptible varieties under phytoplasma infection,ZjGSTU49-ZjGSTU54 in the cluster IV showed opposite expression patterns,which may be due to functional divergence during evolution.Some upregulated genes(ZjGSTU45,ZjGSTU49,ZjGSTU59,and ZjGSTU70)might be involved in the process of jujube against JWB.The yeast two-hybrid results showed that all 6 Tauclass proteins tested could form homodimers or heterodimers.Overall,the comprehensive analysis of the jujube GST gene family revealed that ZjGSTs responded actively to phytoplasma infection.Furthermore,some screened genes(ZjGSTU24,ZjGSTU49-52,ZjGSTU70,and ZjDHAR10)will contribute to further functional studies of jujube-phytoplasma interactions. | Qipeng Wang Liman Zhang Chaoling Xue Yao Zhang Xiangrui Meng Zhiguo Liu Mengjun Liu Jin Zhao | 2024 | Horticultural Plant Journal2024，10，1： | 0 |
| 8 | Size and near-surface engineering in weak-oxidative confined space to fabricate 4 nm L1_(0)-PtCo@Pt nanoparticles for oxygen reduction reaction显示文摘The near-surface structure of the Pt-based alloy including the surface and subsurface structures is prominent to their electrocatalytic performance.Modulating the near-surface structure of PtCo intermetallics with small particle size could efficiently optimize the binding force between Pt and oxygen and finally enhance its oxygen reduction reaction(ORR)performance.Here we simultaneously achieve the size controlling and surface modulation of intermetallic nanoparticles(NPs)in a weak-oxidative confined space with abundant uncoordinated oxygen atoms.1–2 atomic layers of concave Pt-rich surface were successfully constructed on 4 nm L1_(0)-PtCo core after removing Co–O species which is derived from the segregation of the subsurface Co to the surface induced by the uncoordinated oxygen atoms.Owing to the elaborate structure,PtCo-1000/C catalyst shows significant improvement in both activity(1.290 A∙mg_(Pt)^(−1)and 1.529 mA∙cm_(Pt)^(−2) at 0.9 V vs.reversible hydrogen electrode(RHE))and stability(85.2%of initial mass activity after accelerated degression tests(ADTs))even the production is scaled up to gram level.Density functional theory calculations suggest that the cave Pt site optimizes the protonation of*O,which finally boosts the ORR performance. | Yifei Liao Lishan Peng Chaoling Wu Yigang Yan Haijiao Xie Yungui Chen Yao Wang | 2023 | Nano Research2023，16，5： | 0 |
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