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| 1 | Genetic testing in congenital heart disease:A clinical approach显示文摘Congenital heart disease(CHD) is the most common type of birth defect. Traditionally, a polygenic model defined by the interaction of multiple genes and environmental factors was hypothesized to account for different forms of CHD. It is now understood that the contribution of genetics to CHD extends beyond a single unified paradigm. For example, monogenic models and chromosomal abnormalities have been associated with various syndromic and non-syndromic forms of CHD. In such instances, genetic investigation and testing may potentially play an important role in clinical care. A family tree with a detailed phenotypic description serves as the initial screening tool to identify potentially inherited defects and to guide further genetic investigation. The selection of a genetic test is contingent upon the particular diagnostic hypothesis generated by clinical examination. Genetic investigation in CHD may carry the potential to improve prognosis by yielding valuable information with regards to personalized medical care, confidence in the clinical diagnosis, and/or targeted patient followup. Moreover, genetic assessment may serve as a tool to predict recurrence risk, define the pattern of inheritance within a family, and evaluate the need for further family screening. In some circumstances, prenatal or preimplantation genetic screening could identify fetuses or embryos at high risk for CHD. Although genetics may appear to constitute a highly specialized sector of cardiology, basic knowledge regarding inheritance patterns, recurrence risks, and available screening and diagnostic tools, including their strengths and limitations, could assist the treating physician in providing sound counsel. | Marie A Chaix Gregor Andelfinger Paul Khairy | 2016 | World Journal of Cardiology2016，8，2： | 8 |
| 2 | Sens Actuat B Chem 显示文摘 | Hassen W M Chaix C Abdelghani A | 2008 | 134(2): 755-7602008，134，2： | 1 |
| 3 | Surface functionalization of oil-in-water nanoemulsion with a reactive copolymer: Colloidal characterization and peptideimmobilization显示文摘 | Chaix C Pacard E Elassari A | 2003 | Colloids and Surfaces B: Biointerfaces2003，29，1： | 1 |
| 4 | Perspectives on human genetic variation from the HapMap Project 显示文摘 | McVean G Spencer C C A Chaix R | 2005 | PLoS Genetics2005，1，4： | 1 |
| 5 | Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli显示文摘 | Seddi R Chaix JC Puigserver A | 2003 | Protein Expression and Purification2003，27，2： | 1 |
| 6 | Acoustoelastic Eifect in Concrete Material under Uni-axial Compressive Loading 显示文摘 | LILLAMAND I CHAIX J F PLOIX M A | 2010 | Ndt & E International2010，43，8： | 1 |
| 7 | Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli显示文摘 | Seddi R Chaix J C Puigserver A | 2003 | Protein Expr Purif2003，27，2： | 1 |
| 8 | HBV and HCV prevalence and viraemia in HIV - positive and HIV - negative pregnant women in Abidjan, Cote d' Ivoire: the ANRS 1236 study显示文摘 | Rouet F Chaix ML Inwoley A | 2004 | J Med Vir- ol2004，74，1： | 1 |
| 9 | Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges 显示文摘 | Chaix A Zarrinpar A Miu P | 2014 | Cell Metab2014，20，6： | 1 |
| 10 | Diet and feeding pattern affect the diurnal dynamics of the gut microbiome 显示文摘 | Zarrinpar A Chaix A Yooseph S | 2014 | Cell Metab2014，20，6： | 1 |
| 11 | Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli显示文摘 | SEDDI R CHAIX J C PUIGSERVER A | 2003 | Protein Expr Purif2003，27，2： | 1 |
| 12 | Acoustoelastic effect in concrete material under uniaxial compressive loading显示文摘 | Lillamand I Chaix J F Ploix M A | | 0，，： | 1 |
| 13 | Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli显示文摘 | Seddi R Chaix J C Puigserver A | 2003 | Protein Expr Purif2003，27，2： | 1 |
| 14 | Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir显示文摘 | Sagot-Lerolle N Lamine A Chaix ML | 2008 | Aids2008，22，10： | 1 |
| 15 | Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges显示文摘 | CHAIX A ZARRINPAR A MIU P | 2014 | Cell Metab2014，20，6： | 1 |
| 16 | Diet and feeding pattern affect the diurnal dynamics of the gut mierobiome 显示文摘 | ZARRINPAR A CHAIX A YOOSEPH S | 2014 | Cell Metab2014，20，6： | 1 |
| 17 | Efficacy and safety of adefovir dipivoxil in kidney recipients,hemodialys is patients,and patients with renal insufficiency显示文摘 | Fontaine H Vallet-Pichard A Chaix ML | | 0，，08： | 1 |
| 18 | Prolonged valproie acid treatment does not reduce the size of latent HIV reservoir显示文摘 | Sagot-Lerolle N Lamine A Chaix ML | 2008 | Aids2008，22，10： | 1 |
| 19 | Highly active antiretroviral therapy started in infants under 3 months of age:72- week follow-up for CD4 cell count, viral load and drug resistance outcome 显示文摘 | Aboulker JP Babiker A Chaix ML | 2004 | AIDS2004，18，： | 1 |
| 20 | Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli显示文摘 | Seddi R Chaix J C Puigserver A | 2003 | Protein Expr Purif2003，27，2： | 1 |
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