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| 1 | Direct-fed microbes: A tool for improving the utilization of low quality roughages in ruminants显示文摘For many years, ruminant nutritionists and microbiologists have been interested in manipulating the microbial ecosystem of the rumen to improve production efficiency of different ruminant species. Removal and restriction of antibiotics subtherapeutic uses from ruminant diets has amplified interest in improving nutrient utilization and animal performance and search for more safe alternatives. Some bacterial and fungal microorganisms as a direct-fed microbial(DFM) can be the most suitable solutions. Microorganisms that are commonly used in DFM for ruminants may be classified mainly as lactic acid producing bacteria(LAB), lactic acid utilizing bacteria(LUB), or other microorganism's species like Lactobacillus, Bifidobacterium, Enterococcus, Streptococcus, Bacillus, Propionibacterium, Megasphaera elsdenii and Prevotellabryantii, in addition to some fungal species of yeast such as Saccharomyces and Aspergillus. A definitive mode of action for bacterial or fungal DFM has not been established; although a variety of mechanisms have been suggested. Bacterial DFM potentially moderate rumen conditions, and improve weight gain and feed efficiency. Fungal DFM may reduce harmful oxygen from the rumen, prevent excess lactate production, increase feed digestibility, and alter rumen fermentation patterns. DFM may also compete with and inhibit the growth of pathogens, immune system modulation, and modulate microbial balance in the gastrointestinal tract. Improved dry matter intake, milk yield, fat corrected milk yield and milk fat content were obtained with DFM administration. However, the response to DFM is not constant; depending on dosages, feeding times and frequencies, and strains of DFM. Nonetheless, recent studies have supported the positive effects of DFM on ruminant performance. | Mona M Y Elghandour Abdelfattah Z M Salem Jose S Martínez Castaeda Luis M Camacho Ahmed E Kholif Juan C Vázquez Chagoyán | 2015 | Journal of Integrative Agriculture2015，14，3： | 7 |
| 2 | Biological treatments as a mean to improve feed utilization in agriculture animals——An overview显示文摘As a result of agriculture practices, million tons of agriculture are produced as a secondary or by-products; however, with low nutritive values. Many methods are applied to improve the nutritive value and increase its utilization in ruminant's nutrition. The biological treatments are the most common with more safe-treated products. In most cases, the biological treatments are paralleled with decreased crude fiber and fiber fractions content with increased crude protein content. Direct-fed microbial and exogenous enzymes to animal are other ways of biological methods for improving nutritive value of feeds. Here in this review, we will try to cover the biological treatments of by-products from different sides view with different types of animals and different animal end-products. | Nahla A Abdel-Aziz Abdelfattah Z M Salem Mounir M El-Adawy Luis M Camacho Ahmed E Kholif Mona M Y Elghandour Borhami E Borhami | 2015 | Journal of Integrative Agriculture2015，14，3： | 4 |
| 3 | 接受他汀治疗患者新发糖尿病风险:人群为基础的研究显示文摘目的 研究接受HMG-CoA还原酶抑制剂(他汀类药物)治疗的患者的新发糖尿病风险。设计 人群为基础的队列研究,以时间事件分析的方法评估各种他汀类药物应用和新发糖尿病风险的相关性分析。计算危害比(hazard ratios,HR)来确定他汀的种类及剂量与新发糖尿病的关系。 | Aleesa A Caner Tara Gomes Ximena Camacho David N Juurlink Baiju R Shah Muhammad M Mamdani 张秀珍(译) 骆斯慧(译) 翁建平(校) | 2013 | 英国医学杂志中文版2013，16，5： | 2 |
| 4 | Cirrhosis complicating Shwachman-Diamond syndrome: A case report显示文摘BACKGROUND The features of Shwachman-Diamond syndrome (SDS) include exocrine pancreatic insufficiency, skeletal abnormalities and bone marrow dysfunction;an often overlooked feature is hepatic involvement. CASE SUMMARY We report a child who initially presented with failure to thrive and mildly elevated transaminase levels and was determined to have pancreatic insufficiency due to SDS. During follow-up he had persistently elevated transaminase levels and developed hepatosplenomegaly. An investigation was performed to determine the etiology of ongoing liver injury, including a liver biopsy which revealed hepatic cirrhosis. CONCLUSION Cirrhosis has rarely been reported with SDS. While many of the hepatic disorders associated with SDS improve with age, there are rare exceptions with serious implications for long-term outcome. | Sandra M Camacho Lucille McLoughlin Michael J Nowicki | 2019 | World Journal of Clinical Cases2019，7，12： | 2 |
| 5 | Current and novel approaches in the pharmacological treatment of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is one of the most lethal malignant tumours worldwide.The mortality-to-incidence ratio is up to 91.6%in many countries,representing the third leading cause of cancer-related deaths.Systemic drugs,including the multikinase inhibitors sorafenib and lenvatinib,are first-line drugs used in HCC treatment.Unfortunately,these therapies are ineffective in most cases due to late diagnosis and the development of tumour resistance.Thus,novel pharmacological alternatives are urgently needed.For instance,immune checkpoint inhibitors have provided new approaches targeting cells of the immune system.Furthermore,monoclonal antibodies against programmed cell death-1 have shown benefits in HCC patients.In addition,drug combinations,including first-line treatment and immunotherapy,as well as drug repurposing,are promising novel therapeutic alternatives.Here,we review the current and novel pharmacological approaches to fight HCC.Preclinical studies,as well as approved and ongoing clinical trials for liver cancer treatment,are discussed.The pharmacological opportunities analysed here should lead to significant improvement in HCC therapy. | Fernanda Villarruel-Melquiades María Eugenia Mendoza-Garrido Claudia M García-Cuellar Yesennia Sánchez-Pérez Julio Isael Pérez-Carreón Javier Camacho | 2023 | World Journal of Gastroenterology2023，29，17： | 2 |
| 6 | Cerebral Metastasis显示文摘 | Massot Punyet R Almajano J Camacho J M | 2000 | RevNeurol2000，31，12： | 1 |
| 7 | Glucorticoid-induced spinal epidural lipomatosis 显示文摘 | Camacho M Mugnier B Foutrier-Morello C | 2001 | Joint Bone Spine2001，68，4： | 1 |
| 8 | Increased lysophosphatidylcholine and non-esterified fatty acid content in LDL induces chemokine release in endothelial cell:Relationship with electronegative LDL显示文摘 | Benitez S Camacho M Arcelus R Vila L Bancell C Ordonez-Llanos J | 2004 | Atherosclerosis2004，177，2： | 1 |
| 9 | The role of social anxiousness in group brainstorming 显示文摘 | Camacho L M & Paulus P B | 1995 | Journal of Personality and Social Psychology1995，，68： | 1 |
| 10 | Effect of age of feed restriction and microelement supplementa- tion to control ascites on production and carcass charac- teristics of broilers 显示文摘 | Camacho M A Suarez M E Herrera J G | 2004 | Poultry Science2004，，83： | 1 |
| 11 | Influence of locust bean gum/λ-carrageenan mixtures on whipping and mechanical properties and stability of dairy creams 显示文摘 | Camacho M M Martimez--Navarrete N Chiralt A | 1998 | Food Research International1998，31，9： | 1 |
| 12 | MRI segmentation:methods and applications显示文摘 | Clarke L P Ve1thuizen M R P Camacho A | 1995 | Magnita Resonance Imaging1995，13，3： | 1 |
| 13 | Photobioreactors : light Regime, mass transfer, and scale-up 显示文摘 | Grima E M Fernandez F G Camacho F G | 1999 | J Biotechnol1999，70，123： | 1 |
| 14 | Bounded error identification of systems with time-varying parameters 显示文摘 | Bravo J M Alamo T Camacho E F | 2006 | Iggg Transactions on Automatic Control2006，51，7： | 1 |
| 15 | Scale-up of tubu- lar photobioreactors 显示文摘 | Molina E M Fernandez F G Camacho F G | 2000 | J Appl Phycol2000，12，3： | 1 |
| 16 | Sexual Dysfunction in the Elderly: Age or Disease?显示文摘 | Camacho M E Reyes-Ortiz C A | 2005 | Int J Impot Res2005，，： | 1 |
| 17 | Attenuation of postischemic reperfusion injury is related to prevention of overload in rat hearts 显示文摘 | MIYAMAE M CAMACHO SA WEINER MW | 1996 | Am J Physiol1996，271，52： | 1 |
| 18 | MRI markers for mild cognitive impairment:comparisons between white matter integrity and gray matter volume measurements 显示文摘 | Zhang Y Schuff N Camacho M | 2013 | PLoS One2013，8，66： | 1 |
| 19 | Moyamoya disease and sagittal sinus thrombosis in a child with Down's syndrome显示文摘 | De|-Rio Camacho G Omzco AL Perez-Higueras A Camino Lopez M Al-Assir I Ruiz-Moreno M | 2001 | Pediatr Radiol2001，31，2： | 1 |
| 20 | Automated regu- larization parameter selection in multi-scale total variation models for image restoration 显示文摘 | Dong Y Q Hintermuller M Camacho R M M | 2011 | Journal of Mathematical Imaging and Vision2011，40，1： | 1 |
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