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| 1 | Natural history of hepatitis-related hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is an important cause of cancer death in the world.It has great regional differences in the pathology and epidemiology.The variation is greatly influenced by the aetiologies of the disease.Hepatitis B and C infection are the most important risk factors.HCC incidence rates are higher but in decreasing trend in developing countries. However,the figures in the developed countries are contrary.Successful hepatitis B virus(HBV)vaccination programs,better food hygiene,increased global hepatitis C virus(HCV)prevalence and population migration are the possible explanations.A number of clinical and pathogenic differences exist between HBV- and HCV- related HCC.HBV infection leads to the development of HCC through direct and indirect pathways as it has the ability to integrate into the host genome affecting cellular signaling and growth control.HCV causes HCC mainly through indirect pathways:chronic inflammation, cell deaths and proliferation.As a result,HCC is almost exclusively found in cirrhotic HCV patients while HCC is sometimes found in HBV patients without significant liver cirrhosis.Due to the different severities of liver cirrhosis and HCC extent,therapeutic strategies from resection, liver transplantation to symptoms palliation are available. Poorly differentiated histology,lack of fibrous capsule, large tumour size,early vascular invasion and elevated serum levels of alpha fetoprotein(AFP)are the features for more aggressive disease.Combined with markers of liver reserve and performance status,accurate scoring systems and models have been developed to predict patients'survival and match best treatment option. | David Yiu-Kuen But Ching-Lung Lai Man-Fung Yuen | 2008 | World Journal of Gastroenterology2008，14，11： | 56 |
| 2 | Identification of herbal medicinal materials using DNA barcodes显示文摘Herbal medicinal materials have been used worldwide for centuries to maintain health and to treat disease.However,adulteration of herbal medicines remains a major concern of users and industry for reasons of safety and efficacy.Identification of herbal medicinal materials by DNA technology has been widely applied,started from the mid-1990s.In recent years,DNA barcoding of global plant species using four standard barcodes(rbcL,matK,trnH-psbA and ITS) has been a major focus in the fields of biodiversity and conservation.These DNA barcodes can also be used as reliable tools to facilitate the identification of herbal medicinal materials for the safe use of herbs,quality control,and forensic investigation.Many studies have applied these DNA barcodes for the identification of herbal medicinal species and their adulterants.The present article reviews efforts in the identification of herbal medicinal materials using the standard DNA barcodes and other DNA sequence-based markers. | Ming LI Hui CAO Paul Pui-Hay BUT Pang-Chui SHAW | 2011 | Journal of Systematics and Evolution2011，49，3： | 33 |
| 3 | The Induction of Liver Microsomal Cytochrome P450 by Glycyrrhiza uralensis and Glycyrrhetinic acid in Mice显示文摘The effect of Glycyrrhiza uralensis Fisch (GRZ) aqueous extract and one of its active principles Glycyrrhetinic acid (GRT) on hepatic cytochrome P450 in mice were investigated. Oral administration of GRZ at 10g/kg/d or GRT at 50 mg/kg/d for 7 days was foulld to increase the P450 contents up to 4.6 fold compared with the controls. The activities of aryl hydrocarbon hydroxylase (AHH,3. 1 and 3. 3 fold), aminopyrine N-demethylase (ADM, 4. 2 and 3. 2 folds), and 7-ethoxycumarin O-deethylase (ECOD, 2. 8 and 2. 5 fold) were also shown to be increased. Westem blot analysis showed that the subtypes of P450 isoforms induced selectively by GRZ and GRT included CYP1A1 (1. 8 and 1. 5 fold over that of the control, respectively), CYP2B1 (both 1.3 fold), and CYP2C11(3 .2 and 3 .0 fold). Moreover, significant positive correlation between the P450 content or the isoforms and the corresponding enzyme activities mentioned above was observed. | HU WEN-YU LI YA-WEI HOU YAN-NING HE KAN (Department of Pharmacology, Instiute of Materia Medica, Chinese Academy of Medical Scicnces & Beijing Union Medical College, Beijing 100050, China) CHEN JIE-FU (Yang-Ming Medical University, Taipei) BUT PAUL PU | 1999 | Biomedical and Environmental Sciences1999，12，1： | 8 |
| 4 | Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B显示文摘 | Man-Fung Yuen Yasuhito Tanaka Daniel Yee-Tak Fong James Fung Danny Ka-Ho Wong John Chi-Hang Yuen David Yiu-Kuen But Annie On-On Chan Benjamin Chun-Yu Wong Masashi Mizokami Ching-Lung Lai | 2008 | Journal of Hepatology2008，，1： | 5 |
| 5 | Antiviral activities of flavonoids and organic acid from Trollius chinensis Bunge显示文摘 | Yao-Lan Li Shuang-Cheng Ma Yi-Ting Yang Shao-Ming Ye Paul Pui-Hay But | 2002 | Journal of Ethnopharmacology2002，，3： | 3 |
| 6 | HBsAg Seroclearance in Chronic Hepatitis B in Asian Patients: Replicative Level and Risk of Hepatocellular Carcinoma显示文摘 | Man–Fung Yuen Danny Ka–Ho Wong James Fung Philip Ip David But Ivan Hung Kevin Lau John Chi–Hang Yuen Ching–Lung Lai | 2008 | Gastroenterology2008，，4： | 2 |
| 7 | 褐稻虱在越南的发生和迁飞显示文摘水稻是越南的主要粮食作物,种植面积600万公顷.褐稻虱是越南水稻的主要害虫,为害面积每年为10万公顷.迁飞和种植感虫品种是褐稻虱猖獗的主要原因.越南对该虫的防治计划是以筛选抗虫品种为主的综合防治计划. | But Van Ich 刘光杰 胡国文 | 1992 | 国外农学(植物保护)1992，5，3： | 2 |
| 8 | Research on Chinese Medicine at the Chinese University of Hong Kong显示文摘ResearchonChineseMedicineattheChineseUniversityofHongKong￥P.P.H.But(DepartmentofBiologyandChineseMedicinalMaterialResearchCen... | P. P. H. But(Department of Biology and Chinese Medicinal Material Research Centre,The Chinese University of Hong Kong, Shatin, N. T., Hong Kong) | 1997 | Chinese Journal of Integrative Medicine1997，3，1： | 2 |
| 9 | Contribution of molecular cladistics to the taxonomy of Rutaceae in China显示文摘The treatment of Rutaceae in the Chinese flora chose to follow Engler in recognizing Rutoideae and Toddalioideae as two separate subfamilies.Morphological and chemical comparisons,however,suggested group-ing those two subfamilies in one subfamily,Rutoideae.This move has received support from molecular phyloge-netic analyses,which also showed that the Chinese taxa in Euodia should be placed in Tetradium and Melicope following Hartley.Investigations into the chemistry and molecular phylogeny of Murraya also indicated that the species in the section Bergera without yuehchukene should be removed from Murraya.These findings clearly show the value of molecular cladistics to the taxonomy of Rutaceae in China and also directions for further inves-tigations. | Paul Pui-Hay BUT Alice Wing-Sem POON Pang-Chui SHAW Mark P.SIMMONS Harald GREGER | 2009 | Journal of Systematics and Evolution2009，47，2： | 2 |
| 10 | Application of DNA barcodes in Hedyotis L.(Spermacoceae,Rubiaceae)显示文摘The potential application of DNA barcodes of plastid(matK,trnH-psbA,petD,and rbcL) and nuclear(internal transcribed spacer(ITS) of rDNA) DNA regions was investigated for 25 Hedyotis taxa.The ITS showed the best species discrimination by resolving 23 of the species as exclusive lineages with no shared alleles between any of the 24 distinct species(H.assimilis and H.mellii are not supported as distinct species based on our molecular and morphological data).Conversely,rbcL performed the worst and only resolved 10 of the species as exclusive lineages,and 10 species with shared alleles.Using ITS has the advantage of high PCR amplification success and it provides good intra-and interspecific variation distribution patterns.The most powerful plastid markers were petD and trnH-psbA,but we could amplify and sequence trnH-psbA for only 83% of the accessions sampled.Combination of ITS and petD performed extremely well,with all 24 of the distinct species resolved as exclusive lineages and no shared alleles between any of the distinct species.We therefore recommend ITS,or a combination of ITS and petD,as the standard DNA barcode in Hedyotis,but acknowledge that there are no shared alleles between distinct species for matK and rbcL combined. | Xing GUO Mark R SIMMONS Paul Pui-Hay BUT Pang-Chui SHAW Rui-Jiang WANG | 2011 | Journal of Systematics and Evolution2011，49，3： | 2 |
| 11 | Photoluminescence and electrochemiluminescence studies of chosen rare earths systems显示文摘Eu(III) complexes with chosen Keggin polyoxomatalates, POM, containing organic counter cations (tetrabutylammonium, tetrabutylphosphonium, triphenylethylphosphonium), were synthesized, and their photophysical properties were studied. The synthesized complexes had the general formula of XnH5-n[EuSiW11O39], formulated based on the results of elemental and thermogravimetric analysis and FTIR spectroscopy. The photophysical properties of the obtained compounds were investigated using photoluminescence and electro- chemiluminescence, ECL, methods in solutions and solids. The most intense luminescence of Eu(III) was observed for the complexes with tetrabutylammonium cations. After the addition of phenanthroline to the XnH5-n[EuSiW11O39] solutions, a large increase in the Eu(III) lumi- nescence intensity and a lengthening of its luminescence lifetime were observed as a result of the formation of ternary complexes. Attempts to apply ECL as a method of light emission by generating species capable of forming excited states in Ln/POMs, i.e., Tb(III) and Eu(III) in the Na9EuW10O36 and Na9TbW10O36 complexes, were made. The influence of the POM complexes on the ECL was also tested using the Tb/EDDHA (EDDA=ethylenediamine di(o-hydroxyphenylacetic acid)) complex, which is effective in generating ECL. | Stefan Lis Slawomir But Krzysztof Staninski Monika Jesiolowska | 2008 | Journal of Rare Earths2008，26，2： | 2 |
| 12 | 用语料库考察概念的跨文化传播——“知识谱系”项目访谈显示文摘Mona Baker教授是国际知名学者,她对翻译研究特别是语料库翻译研究有极高的学术敏感度,善于捕捉并引领研究的走向。她申报的'知识谱系'(Genealogies of Knowledge)(2016-2020)重大项目获英国艺术与人文研究理事会(AHRC)百万英镑经费支持。在该项目结项之际,赵文静教授等人线上采访了Baker及项目组另外两位主要成员Jan Buts和Henry Jones,以了解课题的设计、概念跨文化迁移的考察路径,以及该项目对中国基于语料库的翻译研究有哪些启发和影响。本刊特请采访者将访谈内容整理并译成中文,供国内同行参考。 | Mona Baker Jan Buts Henry Jones 赵文静 杨国胜 | 2021 | 外语教学与研究2021，53，1： | 2 |
| 13 | Sesquiterpene Lactones from Elephantopus scaber显示文摘 | Paul Pui-Hay But Hon Po-Ming Cao Hui | 1997 | Phytochem1997，44，1： | 1 |
| 14 | Molecular authentication of Panax species显示文摘 | Ngan F Shaw I C But P P H | 1999 | phytochemistry1999，50，5： | 1 |
| 15 | Phanmacognostical identification of American and Oriental ginseng roots by genomic fingerprinting using arbitarily primed polymerose chain reaction(AP- PCR)显示文摘 | Cheung KS Kuan HS But PPH | 1994 | Jethophormacd1994，42，： | 1 |
| 16 | Saccharomyces boulardii produces in rat small intestine a novel protein phosphatase that inhibits EscheNchia coli endotoxin by de- phosphorylation 显示文摘 | Buts JP Dekeyser N Stilmant C | 2006 | Pediatr Res2006，60，1： | 1 |
| 17 | Response of human and small intestinal mucosa to oral administration of Saccharomyces boulardii 显示文摘 | BUTS J P BERNASCONIP | 1986 | Pediatr Res1986，20，： | 1 |
| 18 | Effect of dexmedeto-midine on bleeding during tympanoplastyor septorhinoplasty显示文摘 | Durmus M But A K Dogan Z Yucel A | | 0，，05： | 1 |
| 19 | QUALITY CONTROL FOR CHINESE HERBAL DRUGS USING DNA PROBE TECHNOLOGY显示文摘INTRODUCTIONThetypeandspectrumofdiseasesarechangingsignificantlyasthesocietyagingtoday .Theautoimmunediseasessuchasseniledementia ,AIDS ,aswellascardio cerebralvasculardis easessuchashypertension ,arrhythmia ,myocardiacinfractionearebecominganintractableandglobularproblem .Recently ,peopleareverymuchconcernedwithsideeffectsofsyntheticphar maceuticalsandareanxioustoreturntotheuseofnaturalmedicine .Backtonature ,theneedforChineseherbaldrugsisincreasinggraduallyforpreventionandtherapyofdiseasesintheworld .Arec... | Katsuko KOMATSU Paul Pui Hay BUT | 2002 | 中国实验方剂学杂志2002，8，S1： | 1 |
| 20 | Prevalence and treatment of silent gastro-oesophageal reflux in children with recurrent respairatiory disorders显示文摘 | Buts JP Barudi C Moulin D | 1986 | Eur J Pediatr1986，145，5： | 1 |
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