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| 1 | New-onset diabetes after kidney transplantation:Incidence and associated factors显示文摘AIM To determine the incidence and associated factors of new-onset diabetes after transplantation(NODAT) in a Portuguese central hospital. METHODS This single-center retrospective study involved consecutive adult nondiabetic transplant recipients, who had undergone kidney transplantation between January 2012 and March 2016. NODAT was diagnosed according to the criteria of the American Diabetes Association. Data were collected from an institutional database of the Nephrology and Kidney Transplantation Department(Santa Maria Hospital, Lisbon, Portugal) and augmented with data of laboratorial parameters collected from the corresponding patient electronic medical records. Exclusion criteria were preexisting diabetes mellitus, missing information and follow-up period of less than 12 mo. Data on demographic and clinical characteristics as well as anthropometric and laboratorial parameters were also collected. Patients were divided into two groups: With and without NODAT-for statistical comparison.RESULTS A total of 156 patients received kidney transplantduring the study period, 125 of who were included in our analysis. NODAT was identified in 27.2% of the patients(n = 34; 53% female; mean age: 49.5 ± 10.8 years; median follow-up: 36.4 ± 2.5 mo). The incidence in the first year was 24.8%. The median time to diagnosis was 3.68 ± 5.7 mo after transplantation, and 76.5% of the patients developed NODAT in the first 3 mo. In the group that did not develop NODAT(n = 91), 47% were female, with mean age of 46.4 ± 13.5 years and median follow-up of 35.5 ± 1.6 mo. In the NODAT group, the pretransplant fasting plasma glucose(FPG) levels were significantly higher [101(96.1-105.7) mg/d L vs 92(91.4-95.8) mg/d L, P = 0.007] and pretransplant impaired fasting glucose(IFG) was significantly more frequent(51.5% vs 27.7%, P = 0.01). Higher pretransplant FPG levels and pretransplant IFG were found to be predictive risk factors for NODAT development [odds ratio(OR): 1.059, P = 0.003; OR: 2.772, P = 0.017, respectively]. CONCLUSION NODAT incidence was high in our renal transplant recipients, particularly in the first 3 mo posttransplant, and higher pretransplant FPG level and IFG were risk factors. | Vania Gomes Florbela Ferreira JoséGuerra Maria Joao Bugalho | 2018 | World Journal of Diabetes2018，9，7： | 8 |
| 2 | Low-dose Vaginal misopriostrolflr labor with a live fetus显示文摘 | Bugalho A Bigue C Machungo F | 1995 | Int J Gynaecol Obstet1995，49，2： | 1 |
| 3 | Cognitive function correlates with frontal white matter apparent diffusion coefficients in patients with leukoaraiosis显示文摘 | Viana-Baptista M Bugalho P Jordao C | 2008 | J Neurol2008，255，3： | 1 |
| 4 | RAC1b overexpression in papillary thyroid carcinoma: a role to unravel显示文摘 | Silva AL Carmo F Bugalho MJ | 2013 | Eur J Endocrinol2013，168，6： | 1 |
| 5 | Argon plasma treatment in benign metastasizing leiomyoma of the lung: a case report显示文摘 | Bugalho A Oliveira A Semedo J | 2010 | Rev Port Pneumol2010，16，92： | 1 |
| 6 | Simple method for determination of paraquat in plasma and serum of human patients by high-performance liquid chromatography 显示文摘 | Paixao P Costa P Bugalho T | 2002 | J Chromatogr B2002，775，1： | 1 |
| 7 | Gait disturbance in normal pressure hydrocephalus: a clinical study 显示文摘 | Bugalho P Guimaraes J | 2007 | Parkinsonism Relat Disord2007，13，7： | 1 |
| 8 | Cytokeratin 19, carcinoembryonic antigen, and epithelial cell adhesion molecule detect lung cancer lymph node metastasis in endobronchial ultrasound-guided transbronchial aspiration samples显示文摘 | Bugalho A Martins C Dias SS | 2013 | Clin Lung Cancer2013，14，6： | 1 |
| 9 | Serum vascular endothelial growth factor levels in pa- tients with medullary thyroid carcinoma显示文摘 | JOAO BUGALHO M MADUREIRA D ESPADINHA C | 2008 | Eur J Endocri- nol2008，159，2： | 1 |
| 10 | Set-shifting and behavioral dysfunction in primary focal dystonia显示文摘 | BUGALHO P CORREA B GUIMARAES J | 2008 | Mov Disord2008，23，2： | 1 |
| 11 | Retrospective Analysis of 255 Papillary Thyroid Carcinomas <2 cm: Clinicohistological Features and Prognostic Factors显示文摘 | Marques P Leite V Bugalho MJ | 2014 | Eur Thyroid J2014，3，4： | 1 |
| 12 | Plant wax alkanes and alcohols as herbivore diet composition markers 显示文摘 | Bugalho M N Dove H Kelman W | 2004 | Rangeland Ecology & Management2004，57，3： | 1 |
| 13 | Cuticular wax alkanes and alcohols used as markers to estimate diet composition of sheep(Ovis aries) 显示文摘 | Kelman W Bugalho M Dove H | 2002 | Biochemical Systematics and Ecology2002，4，： | 1 |
| 14 | Cuticular wax alkanes and alcohols used as markers to estimate diet composition of sheep (Ovis aries) 显示文摘 | Kelman W Bugalho M Dove H | 2003 | Biochemical Systematics and Ecology2003，31，8： | 1 |
| 15 | Application of vaginal misoprostol before cervical dilatation to facilitate first-trimester pregnancy interruption 显示文摘 | Bugalho A Bique C A lmeida L | 1994 | Obstet Gynecol1994，83，5： | 1 |
| 16 | REM sleep behavior disorder and motor dysfunction in Parkinson~ s diseaseea longitudinal study 显示文摘 | Bugalho P Viana-Baptista M | 2013 | Parkinson Relat Disord2013，19，： | 1 |
| 17 | Cuticular wax alkanes and alcohols used as markers to estimate diet composition of sheep显示文摘 | Kelman W Bugalho M Dove H | 2003 | Biochemical Systematics and Ecology2003，31，： | 1 |
| 18 | Simple method for determination of paraquat in plasma and serum of human patients by high-performance liquid chromatography 显示文摘 | Paixao P Costa P Bugalho T | 2002 | J Chromatogr B2002，775，1： | 1 |
| 19 | Simple method for determination of paraquat in plasma and serum of human patients by high-performance liquid chromatography 显示文摘 | Paixao P Costa P Bugalho T | 2002 | J Chromatogr B2002，775，1： | 1 |
| 20 | Prevalence of syphilis infection in Mozambique women with second trimestermiscarriage and women attending antenatal care in second trimester显示文摘 | Lindstrand A Bergstrom S Bugalho A | 1993 | Genitourin Med1993，69，： | 1 |
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