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| 1 | Gastric cancer:The times they are a-changin'显示文摘Gastric cancer is the third leading cause of cancer death worldwide.Even though during these last decades gastric cancer incidence decreased in Western countries,it remains endemic and with a high incidence in Eastern countries.The survival in advanced and metastatic stage of gastric cancer is still very poor.Recently the Cancer Genoma Atlas Research Network identified four subtypes with different molecular profiles to classify gastric cancer in order to offer the optimal targeted therapies for pre-selected patients.Indeed,the key point is still the selection of patients for the right treatment,on basis of molecular tumor characterization.Since chemotherapy reached a plateau of efficacy for gastric cancer,the combination between cytotoxic therapy and biological agents gets a better prognosis and decreases chemotherapeutic toxicity.Currently,Trastuzumab in combination with platinum and fluorouracil is the only approved targeted therapy in the first line for c-erb B2 positive patients,whereas Ramucirumab is the only approved targeted agent for patients with metastatic gastric cancer.New perspectives for an effective treatment derived from the immunotherapeutic strategies.Here,we report an overview on gastric cancer treatments,with particular attention to recent advances in targeted therapies and in immunotherapeutic approach. | Maria Antonietta Satolli Lucio Buffoni Rosella Spadi Ilaria Roato | 2015 | World Journal of Gastrointestinal Oncology2015，7，11： | 6 |
| 2 | Nutrient profiles in the pore water of a deltaic lagoon: Methodological considerations and evaluation of benthic fluxes 显示文摘 | Viel M Barbanti A Langone L Buffoni G Paltfinieri D Rosso G | 1991 | Estuar Coastal Shelf Sci1991，33，4： | 1 |
| 3 | DNA repair gene expression level in peripheral blood and tumour tissue from non- small cell lung cancer and head and neck squamous cell cancer- patients显示文摘 | Schena M Guarrera S Buffoni L | 2012 | DNA Repair(Amst)2012，11，4： | 1 |
| 4 | Early rehabilitation of facial nerve deficit after acoustic neuroma sur-gery显示文摘 | Barbara M Monini S Buffoni A | 2003 | Acta Otolaryngol2003，123，8： | 1 |
| 5 | Trends of minimum and maximum daily temperatures in Italy from 1865 to 1996显示文摘 | Brunetti M Buffoni L Maugeri M | 2000 | Theoretical and Applied Climatology2000，66，： | 1 |
| 6 | Nickel catalysts applied in steam reforming of gly-cerol for hydrogen production显示文摘 | Buffoni Ivana N Pompeo Francisco Santori Gerardo F | 2009 | Catalysis Communica-tions2009，10，： | 1 |
| 7 | Temperature, precipitation and extreme events during the last century in Italy显示文摘 | Brunetti M Buffoni L Mangianti F | 2004 | Global and Planetary Change2004，40，： | 1 |
| 8 | Second-line chemotherapy with weekly paclitaxel and gemcitabine in patients with small-cell lung cancer pretreated with platinum and etoposide: a single institution phase II trial 显示文摘 | Dongiovanni V Buffoni L Berruti A | 2006 | Cancer Chemothe Pharmacol2006，58，2： | 1 |
| 9 | Precipitation in Italy from 1833 to 1966显示文摘 | Buffoni L Maugeri M Nani T | 1999 | Theor and Appl Climatol1999，63，： | 1 |
| 10 | Precipitation in Italy from 1833 to 1996显示文摘 | Buffoni L Maugeri M Nanni T | 1999 | Theoretical Applied Climatology1999，63，： | 1 |
| 11 | Precipitation in Italy from 1833 to 1996显示文摘 | Buffoni L M Maugeri T Nanni | 1999 | Theoretical and Applied Climatology1999，63，： | 1 |
| 12 | Temperature, precipitation and extreme events during the last century in Italy显示文摘 | Brunetti M Buffoni L Mangianti F | 2004 | Global and Planetary Change2004，40，1： | 1 |
| 13 | Spontaneous osteoclastogenesis is apredictivefactor for bonemetastases from non-smallcelllungcancer显示文摘 | Roato I Gorassini E Buffoni L | | 0，，01： | 1 |
| 14 | Investigating the relationship between raw milk bacterial composition,as described by intergenic transcribed spacer-PCR fingerprinting,and pasture altitude显示文摘 | I Bonizzi J N Buffoni M Feligini | | 0，，： | 1 |
| 15 | Semicarbazide-sensitive amine oxidase activity of guinea pig dorsal skin 显示文摘 | BUFFONI F CAMBI S BANCHELLI G | 1994 | J Neural Transm Suppl1994，41，： | 1 |
| 16 | DNA repair gene expression levelin peripheral blood and tumour tissue from non-small cell lungcancer and head and neck squamous cell cancer patients显示文摘 | Schena M Guarrera S Buffoni L | 2012 | DNARepair(Amst)2012，11，： | 1 |
| 17 | Precipitation in Italy from 1833 to 1996显示文摘 | BUFFONI L MAUGERI M NANNI T | 1999 | Theoretical and Applied Climatology1999，63，： | 1 |
| 18 | UV-induced changes in pigment content and light penetration in the fruticose lichen Cladonia arbuscular显示文摘 | ROBERTA S BUFFONI H JANET F B | 2002 | J Photoch Photobio B2002，66，1： | 1 |
| 19 | Identification ofmicrobiota present on the surface of Taleggio cheese using PCR-DGGE and RAPD-PCR 显示文摘 | Feligini M Panelli S Buffoni J N | 2012 | Food Science2012，77，11： | 1 |
| 20 | Early rehabilitation of facial nerve deficil after neuroma surgery显示文摘 | Barbara M Monini S Buffoni A | 2003 | Acta Otolaryngol2003，123，8： | 1 |
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