2篇
您的检索式：作者名="Bryan Ferrigno"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bioactive polymeric materials and electrical stimulation strategies for musculoskeletal tissue repair and regeneration显示文摘Electrical stimulation(ES)is predominantly used as a physical therapy modality to promote tissue healing and functional recovery.Research efforts in both laboratory and clinical settings have shown the beneficial effects of this technique for the repair and regeneration of damaged tissues,which include muscle,bone,skin,nerve,tendons,and ligaments.The collective findings of these studies suggest ES enhances cell proliferation,extracellular matrix(ECM)production,secretion of several cytokines,and vasculature development leading to better tissue regeneration in multiple tissues.However,there is still a gap in the clinical relevance for ES to better repair tissue interfaces,as ES applied clinically is ineffective on deeper tissue.The use of a conducting material can transmit the stimulation applied from skin electrodes to the desired tissue and lead to an increased function on the repair of that tissue.Ionically conductive(IC)polymeric scaffolds in conjunction with ES may provide solutions to utilize this approach effectively.Injectable IC formulations and their scaffolds may provide solutions for applying ES into difficult to reach tissue types to enable tissue repair and regeneration.A better understanding of ES-mediated cell differentiation and associated molecular mechanisms including the immune response will allow standardization of procedures applicable for the next generation of regenerative medicine.ES,along with the use of IC scaffolds is more than sufficient for use as a treatment option for single tissue healing and may fulfill a role in interfacing multiple tissue types during the repair process. | Bryan Ferrigno Rosalie Bordett Nithyadevi Duraisamy Joshua Moskow Michael R.Arul Swetha Rudraiah Syam P.Nukavarapu Anthony T.Vella Sangamesh G.Kumbar | 2020 | Bioactive Materials2020，5，3： | 8 |
| 2 | Review: Bioengineering approach for the repair and regeneration of peripheral nerve显示文摘Complex craniofacial surgeries of damaged tissues have several limitations,which present complications and challenges when trying to replicate facial function and structure.Traditional treatment techniques have shown suitable nerve function regeneration with various drawbacks.As technology continues to advance,new methods have been explored in order to regenerate damaged nerves in an effort to more efficiently and effectively regain original function and structure.This article will summarize recent bioengineering strategies involving biodegradable composite scaffolds,bioactive factors,and external stimuli alone or in combination to support peripheral nerve regeneration.Particular emphasis is made on the contributions of growth factors and electrical stimulation on the regenerative process. | Joshua Moskow Bryan Ferrigno Nikhil Mistry Devina Jaiswal Ketan Bulsara Swetha Rudraiah Sangamesh G.Kumbar | 2019 | Bioactive Materials2019，4，1： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员