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| 1 | The performance characteristics of prostate-specific antigen and prostate-specific antigen density in Chinese men显示文摘我们在中国人调查了前列腺特定的抗原(PSA ) 和 PSA 密度(PSAD ) 的表演特征。经历了 transrectal 的所有中国人到 2013 的从 2000 年的指导超声的前列腺活体检视(TRUS-PB ) 被包括。为 PSA 和 PSAD 操作特征(巨鸟) 曲线的接收装置被分析。敏感,特性,积极预兆的价值(PPV ) 和在不同截止层次的否定预兆的价值(NPV ) 是计算的。2606 个中国人的一个总数被包括。为 ROC,在曲线下面的区域为 PSA 是 0.770 (P <0.001 ) 并且 0.823 为 PSAD (P <0.001 ) 。4.5 ng ml −1 的 PSA 94.4% 的有的敏感, 14.1% 的特性, 29.5% 的 PPV,和 86.9% 的 NPV;0.12 ng ml −1 cc −1 的 PSAD 有 94.5% 的敏感, 26.6% 的特性, 32.8% 的 PPV,和 92.7% 的 NPV。在逻辑回归分析的 multivariate 上,在 4.5 ng ml −1 截止的 PSA (或 1.61, 95% CI 1.05-2.45, P = 0.029 ) 并且在 0.12 ng ml −1 cc 截止的 PSAD −1( 或 6.22, 95% CI 4.20-9.22, P <0.001 ) 是为 TRUS-PB 上的前列腺癌症察觉的重要预言者。在结论,在在中国人的不同截止层次的 PSA 和 PSAD 的表演与在白种人的那些很不同。4.5 ng ml −1 的 PSA 和 0.12 ng ml −1 cc −1 的 PSAD 在 95% 敏感附近有并且是在中国人的前列腺癌症察觉的重要预言者。 | Jeremv YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 13 |
| 2 | 经直肠超声引导下穿刺活检诊断前列腺癌与直肠指检和前列腺特异性抗原水平的关系:在中国人群中的情况如何?显示文摘我们分析了经直肠超声引导下穿刺活检后前列腺癌的检出率与直肠指检和前列腺特异性抗原水平的关系以及中国人群检出前列腺癌的危险因素。我们从数据库中检索了自2000年到2013年所有首次接受经直肠超声引导下前列腺穿刺活检的中国男性的数据。结合直肠指检的发现以及前列腺特异性抗原水平(〈 4, 4-10, 10.1-20,20.1-50 , 〉 50ng/ml)分析了前列腺癌的检出率。使用多因素Logistic回归研究了前列腺癌检出的潜在危险因素。共有2606中国男性人群纳入该研究。在直肠指检正常的患者中,不同前列腺特异性抗原水平(〈 4, 4-10,10.1-20, 20.1-50, 〉 50 ng/ml)患者前列腺癌的检出率分别为8.6%,13.4%,21.8%,41.7%和85.2%。在直肠指检异常的患者中,不同前列腺特异性抗原水平(〈 4, 4-10, 10.1-20, 20.1-50, 〉 50 ng/ml)患者前列腺癌的检出率分别为12.4%, 30.2%, 52.7%, 80.6%和96.4%。多因素Logistic回归分析提示:老龄、较小的前列腺体积、更多针数的穿刺活检、直肠指检异常发现、较高的PSA水平都与增大的前列腺癌检出风险相关(P 〈0.001)。与西方人群相比,中国男性人群的前列腺癌检出率较低。考虑到不同的危险因素,可以采用个体化的方式来决定是否采取经直肠超声引导下穿刺活检。 | Jeremy YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu | 2015 | Asian Journal of Andrology2015，17，5： | 4 |
| 3 | A meta-analysis of the relation of job characteristics to job satisfaction显示文摘 | Brian TL Raymond AN | 1985 | Journal of Applied Psychology1985，70，2： | 1 |
| 4 | β1- Adrenergic receptor polymorphisms and clinical efficacy of betaxolol hydrochloride in normal vohmteers 显示文摘 | Stephen GS Brian JP Robert CA Ivan GC Christopher TL | 2005 | Ophthalmology2005，112，12： | 1 |
| 5 | A meta--analysis of the relation of job characteristics to job satisfaction 显示文摘 | BRIAN TL RAYMOND AN | 1985 | Journal of Applied Psychology1985，70，2： | 1 |
| 6 | Hlx homeobox transcription factor negatively regulates interferon-γ production in monokine-aetivated natural killer cells显示文摘 | Brian B Hughes TL Freud AG | 2007 | Blood2007，109，6： | 1 |
| 7 | Multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy with semi-robotic navigation in the Chinese population: initial results显示文摘 | Wai Kit Ma Brian SH HO Andrew SH Lai Ka Cheong Lam Yun Sang Chan Lawrance KC Yip Ada TL Ng James HL Tsu Ming Kwong Yiu | 2018 | Asian Journal of Andrology2018，20，1： | 0 |
| 8 | The utility of coronary computed tomography angiography in elderly patients显示文摘Background Coronary computed tomography angiography(CCTA)is often avoided in elderly patients due to a presumption that a high proportion of patients will have heavily calcified plaque limiting an accurate assessment.We sought to assess the image quality,luminal stenosis and utility of CCTA in elderly patients with suspected coronary artery disease(CAD)and stable chest pain.Methods Retrospective analysis of elderly patients(>75 years)who underwent 320-detector row CCTA between 2012–2017 at MonashHeart.The CCTA was analysed for degree maximal coronary stenosis by CAD-RADS classification,image quality by a 5-point Likert score(1-poor,2-adequate,3-good,4-very good,5-excellent)and presence of artefact limiting interpretability.Results 1011 elderly patients(62%females,78.8±3.3 years)were studied.Cardiovascular risk factor prevalence included:hypertension(65%),hyperlipidaemia(48%),diabetes(19%)and smoking(21%).The CCTA was evaluable in 68%of patients which included 52%with non-obstructive CAD(<50%stenosis),48%with obstructive CAD(>50%)stenosis.Mean Likert score was 3.1±0.6 corresponding to good image quality.Of the 323(32%)of patients with a non-interpretable CCTA,80%were due to calcified plaque and 20%due to motion artefact.Male gender(P=0.009),age(P=0.02),excess motion(P<0.01)and diabetes mellitus(P=0.03)were associated with non-interpretable CCTA.Conclusion Although CCTA is a feasible non-invasive tool for assessment of elderly patients with stable chest pain,clinicians should still be cautious about referring elderly patients for CCTA.Patients who are male,diabetic and>78 years of age are significantly less likely to have interpretable scans. | Jordan Laggoune Nitesh Nerlekar Kiran Munnur Brian SH Ko James D Cameron Sujith Seneviratne Dennis TL Wong | 2019 | Journal of Geriatric Cardiology2019，16，7： | 0 |
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