|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Meeting the challenges of HIV/AIDS in Southeast and East Asia显示文摘 | Nicola P Brenda SAY | 2005 | Asia Pacific Viewpoint2005，46，1： | 1 |
| 3 | City branding: Can goods and services branding models be used to brand cities? 显示文摘 | Brenda P John S | 2005 | Place Brandjing2005，2，3： | 1 |
| 4 | PLFA Analyses of microbialcommunities associated with PAH-contaminated river-banksediment显示文摘 | Brenda P Roland R Carl J G | 2012 | Microbial Ecology2012，64，： | 1 |
| 5 | An Antifungal Tetrapeptide from the culture of Penicillium canescens 显示文摘 | Brenda V B Nora I P Gabriela M C | 2009 | Chem Biod2009，6，8： | 1 |
| 6 | Improvlng image quality in poor visibility conditions using a physical model for contrast degrsdation 显示文摘 | Oakley John P Satherley Brenda L | 1998 | IEEE Transactions on Image Processing1998，7，2： | 1 |
| 7 | Meeting the challenges of HIV/AIDS in Southeast and East Asia 显示文摘 | Nicola P Brenda SAY | 2005 | Asia Pacific Viewpoint2005，46，1： | 1 |
| 8 | Molecular sensing of 3-chloro-1,2-propanediol by molecular imprinting显示文摘 | Leung Mitch K P Chiu Brenda K W Lam Michael H W | 2003 | Analytica Chimica Acta2003，491，： | 1 |
| 9 | Fostering creativity in nursing students:a blending of nursing and the arts 显示文摘 | Brenda P | 2011 | Holist Nurs Pract2011，25，1： | 1 |
| 10 | Why Zijinshan copper bioheapleaching plant works efficiently at low microbial activity-study on leaching kinetics of copper sulfides and its implications 显示文摘 | Ruan R M Zou G Zhong S P Wu Z L Chan Brenda Wang D Z | 2013 | Minerals Engineering2013，48，4： | 1 |
| 11 | Activated systemic inflammatory response at diagnosis reduces lymph node count in colonic carcinoma显示文摘AIM: To investigate a link between lymph node yield and systemic inflammatory response in colon cancer. METHODS: A prospectively maintained database was interrogated. All patients undergoing curative colonic resection were included. Neutrophil lymphocyte ratio(NLR) and albumin were used as markers of SIR. In keeping with previously studies, NLR ≥ 4, albumin < 35 was used as cut off points for SIR. Statistical analysis was performed using 2 sample t-test and χ~2 tests where appropriate.RESULTS: Three hundred and two patients were included for analysis. One hundred and ninety-five patients had NLR < 4 and 107 had NLR ≥ 4. There was no difference in age or sex between groups. Patients with NLR of ≥ 4 had lower mean lymph node yields than patients with NLR < 4 [17.6 ± 7.1 vs 19.2 ± 7.9(P = 0.036)]. More patients with an elevated NLR had node positive disease and an increased lymph node ratio(≥ 0.25, P = 0.044). CONCLUSION: Prognosis in colon cancer is intimately linked to the patient’s immune response. Assuming standardised surgical technique and sub specialty pathology, lymph node count is reduced when systemic inflammatory response is activated. | Rory P Kennelly Brenda Murphy John O Larkin Brian J Mehigan Paul H McCormick | 2016 | World Journal of Gastrointestinal Oncology2016，8，8： | 1 |
| 12 | Associations between common polymorphisms in TP53 and p21WAF1/Cipl and phenotypic features of breast cancer 显示文摘 | Brenda L P Iris L S Paul R | 2002 | Carcinogenesis2002，23，2： | 1 |
| 13 | Improving image qual- ity in poor visibility conditions using a physical model for contrast degradation 显示文摘 | John P Oakley Brenda L Satherley | 1998 | IEEE Transactions on Image Processing1998，7，2： | 1 |
| 14 | Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits显示文摘 | Lema H Amanda B | 2005 | J Clin Endocrinol Metab2005，90，5： | 1 |
| 15 | Does Corporate Social Responsibility Orientation Vary by Po- sition in the Organtional hierarchy 显示文摘 | John P Angelidis Brenda L Massetti Pauline Magee-Egan | 2008 | Review of Business2008，，： | 1 |
| 16 | Investigation of AOT reverse microemulsions in supercritical carbon dioxide显示文摘 | Brenda H H Jilska M P Franz G | 1999 | Colloids and surfaces A1999，146，： | 1 |
| 17 | Neural stem cells and cell replacement therapy: making the right ceils 显示文摘 | Angela Bithell Brenda P | 2005 | Clin Sci2005，108，1： | 1 |
| 18 | Autologous fat grafts: a quantitative and morphometric study in rabbits显示文摘 | MARQUES A BRENDA E SALDIVA P H | 1994 | Scand J Plast Reeonstr Surg Hand Surg1994，28，4： | 1 |
| 19 | Enzyme entrapment in liposomes 显示文摘 | G Gregoriadis P D Leathwood Brenda E Ryman | 1971 | FEBS Letters1971，14，2： | 1 |
| 20 | Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer显示文摘 | Brenda L P Iris L S Paul R | 2002 | Carcinogenesis2002，23，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员