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69篇 您的检索式:作者名="Breedam"
    题名 作者 年代 出处 被引量
1Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus显示文摘VAN GORP H VAN BREEDAM W DELPUTTE P L 2008J Gen Virol2008,89,12:1
2Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus显示文摘Van Gorp H Van Breedam W Van Doorsselaere J 2010J Virol2010,84,6:1
3Identification of the CD163 protein domains in-volved in infection of the porcine reproductive and respiratory syndrome virus显示文摘VAN GORP H VAN BREEDAM W VAN DOORSSELAE- RE J 2010J Viro12010,84,6:1
4Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus显示文摘Van Gorp H Van Breedam W Delputte P L 0,,12:1
5Comparing descent heuristics and me- taheuristics for the vehicle routing problem 显示文摘Van Breedam A 2001Comput- ers and Operations Research2001,,28:1
6Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus显示文摘Van Gorp H Van Breedam W Van Doorsselaere J 2010J Virol2010,84,6:1
7Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage显示文摘Van Breedam W Delputte P L Van gorp H 2010J Gen Virol2010,91,7:1
8Improvement heuristics for the vehicle routing problem based on simulated annealing显示文摘Van BREEDAM A 1995European Journal of Operational Research1995,86,3:1
9IFN-a treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin 显示文摘DELPUTTE P L VAN BREEDAM W BARBE F 2007J Interferon Cytokine Res2007,27,9:1
10Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus显示文摘Van Gorp H Van Breedam W Delputte P L 2008J Gen Virol2008,89,12:1
11Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus 显示文摘Van Gorp H Van Breedam W Delputte P L 2008J Gen Virol2008,89,12:1
12The M/GP5glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner显示文摘Van Breedam W Van Gorp H Zhang J Q 2010PLoS Pathogens2010,6,10:1
13Identi- fication of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus 显示文摘Van Gorp H Van Breedam W Van Doorsselaere J 2010Journal of virology2010,84,6:1
14Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage 显示文摘Van Breedam W Delputte P L Van Gorp H 2010J Gen Virol2010,91,7:1
15Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection 显示文摘Karniychuk U U Van Breedam W Van Roy N 2012Vet Res2012,43,:1
16Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus 显示文摘Van Gorp H Van Breedam W Delputte P L 2008J GenVirol2008,89,12:1
17猪繁殖与呼吸综合征病毒M/GP5糖蛋白复合物可通过唾液酸依赖途径与唾液酸黏附素受体结合显示文摘猪繁殖与呼吸综合征病毒(PRRSV)是世界范围内威胁猪健康的最主要的因素,被认为是当今养猪业中最重要的病毒病。在过去的几年中,对病毒侵入宿主细胞的研究使许多病毒受体及病毒进入调控因子被鉴定出来。然而,与这些大分子相对应的病毒组分仍不清楚,这使得合理开发新型疫苗变得很困难。该研究的主要目的是鉴定巨噬细胞上的关键性PRRSV受体—唾液酸黏附素相对应的病毒组分。为此,作者构建了可溶性的唾液酸黏附素并对其进行验证。在唾液酸依赖途径中,可溶性的唾液酸黏附素可以与PRRSV结合,并阻断PRRSV对巨噬细胞的感染,因此可以确定唾液酸黏附素是巨噬细胞上PRRSV所必需的受体。尽管唾液酸也存在于膜糖蛋白GP3、GP4和GP5中,但是只有PRRSV的M/GP5糖蛋白复合物被证实为唾液酸黏附素的配基。试验结果发现,两者之间的相互作用依赖于唾液酸黏附素结合唾液酸的能力及GP5上的唾液酸。这些研究结果不仅有利于更好的了解PRRSV的生物学特性,而且该研究结果及研究方法是开发PRRSV新型疫苗的关键。Wander Van Breedam 邱文英 2010中国畜牧兽医2010,37,3:1
18Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage显示文摘Van Breedam W Delputte PL Van Gorp H 2010J Gen Virol2010,91,7:1
19Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage 显示文摘VAN BREEDAM W DELPUTTE P L VAN GORP H 2010JGen Virol2010,9,:1
20Porcinereproductive and respiratory syndrome virus entry into theporcine macrophage显示文摘Van Breedam W Delputte P L Van Gorp H 2010J Gen Virol2010,91,7:1
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