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50篇 您的检索式：作者名="Brante G"

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	题名	作者	年代	出处	被引量
1	Colonic ulcerations may predict steroid-refractory course in patients with ipilimumab-mediated enterocolitis显示文摘AIM To investigate management of patients who develop ipilimumab-mediated enterocolitis, including association of endoscopic findings with steroid-refractory symptoms and utility of infliximab as second-line therapy.METHODS We retrospectively reviewed all patients at our centerwith metastatic melanoma who were treated with ipilimumab between March 2011 and May 2014. All patients received a standard regimen of intravenous ipilimumab 3 mg/kg every 3 wk for four doses or until therapy was stopped due to toxicity or disease progression. Basic demographic and clinical data were collected on all patients. For patients who developed grade 2 or worse diarrhea(increase of 4 bowel movements per day), additional data were collected regarding details of gastrointestinal symptoms, endoscopic findings and treatment course. Descriptive statistics were used.RESULTS A total of 114 patients were treated with ipilimumab during the study period and all were included. Sixteen patients(14%) developed ≥ grade 2 diarrhea. All patients were treated with high-dose corticosteroids(1-2 mg/kg prednisone daily or equivalent). Nine of 16 patients(56%) had ongoing diarrhea despite highdose steroids. Steroid-refractory patients received one dose of intravenous infliximab at 5 mg/kg, and all but one had brisk resolution of diarrhea. Fourteen of the patients underwent either colonoscopy or sigmoidoscopy with variable endoscopic findings, ranging from mild erythema to colonic ulcers. Among 8 patients with ulcers demonstrated by sigmoidoscopy or colonoscopy, 7 patients(88%) developed steroidrefractory symptoms requiring infliximab. With a median follow-up of 264 d, no major adverse events associated with prednisone or infliximab were reported.CONCLUSION In patients with ipilimumab-mediated enterocolitis, the presence of colonic ulcers on endoscopy was associated with a steroid-refractory course.	Animesh Jain Evan J Lipson William H Sharfman Steven R Brant Mark G Lazarev	2017	World Journal of Gastroenterology2017，23，11：	8
2	Gamma glutamyltransferase as a risk factor for cardiovascular disease mortality:an epidemiological investigation in a cohort of 163,944 Austrian adults显示文摘	Ruttmann E Brant L J Conein H Diem G Rapp K Ulmer H	2005	Circulation2005，112，：	1
3	Nonlinear absorption study of a C60-toluene solution显示文摘	McLean D G Sutherland R L Brant M C	1993	Opt Lett1993，18，11：	1
4	Sulfur hexafluoride and the electric power industry显示文摘	Christophorou L G OlthoffJ K Van Brant R J	1997	IEEE Transactions on Electrical Insulation1997，13，5：	1
5	A spectrophotometric method for detecting blood in white-shell eggs显示文摘	Brant A W Norris K H Chin G	1953	Poultry Scienc1953，32，2：	1
6	Light- scattering investigation of the temperature-driven conformationchange in xanthan显示文摘	HACCHE L S WASHINGTON G E BRANT D A	1987	Macromolecules1987，20，9：	1
7	Effects of ventriculoperitoneal shunt on cerebral oxygenation and brain compliance in chronic obstractive hydrocephalus 显示文摘	Mark G Christine L Brant'MS	2001	J Neurosurg2001，94，4：	1
8	Introduction: Judicial Applications of artificial intelligence 显示文摘	G Sartor L Karl Branting	1998	Artificial Intelligence and Law1998，6，24：	1
9	Energy efficiency analysis of some cooperative and non-cooperative transmission schemes in wireless sensor networks 显示文摘	Brante G Kakitani M T Souza R D	2011	IEEE Transactions on Communica- tions2011，59，10：	1
10	Fast and sensitive silver staining of DNA in polyacrylamide gels 显示文摘	Brant J B Gustavo C A Peter M G	1991	Anal Bioehem1991，196，1：	1
11	Fast and sensitive silver staining of DNA in polyacrylamide gels显示文摘	BRANT J CAETANO-ANOLLES G GRESSOFF P M	1991	Analytical Biochemistry1991，195，：	1
12	Spatial diversity using analog joint source channel coding in wireless channels显示文摘	BRANTE G SOUZA R D GARCIA J	2013	IEEE Transactions on Communications2013，61，1：	1
13	Fast and sensitive silver staining of DNA in polyacrylamide gels显示文摘	Brant J B Gustavo C A Peter M G	1991	Anal Biochem1991，196，：	1
14	Fast and sensitive silver Staining of DNA in polyacrylamide gels显示文摘	Brant J B Gustabo C A Petter M G	1991	Anal Biochem1991，196，：	1
15	Fast and sensitive Silver Staining of DNA in Polyacrylamide Gels显示文摘	Brant J B Gustavo C A Peter M G	1991	Analytical Biochemistry1991，196，：	1
16	Thermomechanical analysis of coal ash-the influence of the material for the sample assembly显示文摘	Brant G W Browning G J Gupta S K	2000	Energy and Fuels2000，14，：	1
17	The sequence statistics and solution conformation of a barley (1→3) (1→4) -β-D-glucan 显示文摘	Buliga G S Brant D A Fincher G B	1986	Carbohydrate Research1986，157，：	1
18	Roll-gap temperature models for hot mills显示文摘	Heselton M O	1982	Metall Technol1982，9，：	1
19	Development of a high fidelity ltmar soil stimulant显示文摘	ROBERT J G BRANT C W MARTY A G	2008	Space Technology and Applications International Forum2008，6，：	1
20	Fast and Sensitive Silver Staining of DNA in Polyacrylamide Gels显示文摘	Brant J B Gustavo C A Peter M G	1991	analytieal biochemistry1991，196，：	1

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