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| 1 | 体质指数和腰围对浙江地区成年人糖尿病发生影响的前瞻性研究显示文摘目的 探讨BMI和腰围对成年人糖尿病发病的影响。方法 使用"中国慢性病前瞻性研究"(CKB)浙江省桐乡市数据,剔除基线时自报患有恶性肿瘤、心脏病、脑卒中和糖尿病患者后,纳入分析30-79岁53 916人。采用Cox比例风险模型计算糖尿病发病风险比(HR)。结果 调查对象累计随访391 512人年(平均随访7.26年)。随访期间,男性944人和女性1 643人被新诊断为糖尿病。多因素调整后,与BMI正常组的人群相比,男性超重和肥胖组糖尿病发病的HR值(95%CI)分别为2.72(95%CI:2.47-2.99)和6.27(95%CI:5.33-7.36)。女性超重和肥胖组HR值(95%CI)分别为2.19(95%CI:2.04-2.36)和3.78(95%CI:3.36-4.26);与腰围正常组的人群相比,男性Ⅰ级(85.0-89.9)和Ⅱ级中心性肥胖(≥ 90.0)组糖尿病发病的HR值(95%CI)分别为2.56(2.22-2.95)和4.66(4.14-5.24)。女性Ⅰ级(80.0-84.9)和Ⅱ级中心性肥胖(≥ 85.0)组HR值(95%CI)分别为1.99(1.80-2.21)和3.16(2.90-3.44)。结论 超重/肥胖以及中心性肥胖人群糖尿病发病风险均会升高。在开展控制体重预防糖尿病的同时,更应控制腰围。 | 王浩 胡如英 钱一建 王春梅 谢开婿 陈玲琍 潘东霞 张益丹 卞铮 郭彧 Fiona Bragg 俞敏 李立明 陈铮鸣 | 2018 | 中华流行病学杂志2018，39，6： | 20 |
| 2 | 鼻气管鸟疫杆菌中国株的鉴定显示文摘通过形态特征检验、常规生长实验、API-20NE生化试剂盒检验、PCR检验和血清学检验从疑似副鸡嗜血杆菌的野外分离株中鉴定出2株鼻气管鸟疫杆菌。 | 陈小玲 宋程 罗廷荣 宋敏训 Terry T Bragg R Blackall P.J. | 2004 | 中国家禽2004，26，18： | 13 |
| 3 | Role of the JNK signal transduction pathway in inflammatory bowel disease显示文摘The c-Jun NH2-terminal Kinase (JNK) pathway representsone sub-group of the mitogen-activated protein (MAP)kinases which plays an important role in variousinflammatory diseases states, including inflammatorybowel disease (IBD). Significant progress towardsunderstanding the function of the JNK signaling pathwayhas been achieved during the past few years. Blockadeof the JNK pathway with JNK inhibitors in animal modelsof IBD lead to resolution of intestinal inflammation.Current data suggest specific JNK inhibitors hold promiseas novel therapies in IBD. | Praveen K Roy Farzana Rashid Jack Bragg Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008，14，2： | 10 |
| 4 | 中国成人糖尿病、血糖与结直肠癌发病率:针对50万人的前瞻性研究显示文摘背景糖尿病可致结直肠癌(CRC)的发病风险升高。糖尿病病程和非糖尿病患者的血糖与CRC发病风险之间的相关性仍不清楚。方法2004至2008年前瞻性中国Kadoofe Biobank研究从10个不同地区纳入了512 713名受试者。在10年随访期间,在基线无癌症史的510 136名受试者中共记录有3 024例新发CRC病例(1 745例结肠癌,1 716例直肠癌)。应用Cox回归分析对糖尿病(入组前诊断或筛查发现的)或无糖尿病病史者随机血糖(RPG)水平与CRC发病相关性的校正风险比(HR)进行估计。结果基线时,共有5.8%的受试者患有糖尿病。糖尿病患者发生CRC的校正HR为1.18(95%可信区间1.04~1.33),且发生结肠癌与直肠癌的风险相当[1.19(1.01~1.39)比1.14(0.96~1135)]。这些患者发生CRC的HR随糖尿病病程的延长而下降(趋势P值为0.03)。在入组前无糖尿病的受试者中,其RPG水平与CRC发病呈正相关,基线RPG每升高1 mmol/L其发生CRC的校正HR为1.04(1.02~1.05),且发生结肠癌与直肠癌的风险亦相当[1.03(1.01~1.05)比1.04(1.02~1.06)]。在男性中,糖尿病和RPG与CRC发病风险的相关性高于女性,但其差异无统计学意义(异质性检验的P值分别为0.3和0.2)。讨论在中国成年人中,未诊断糖尿病者其糖尿病和升高的血糖水平与CRC发病风险升高相关。 | Yuanjie Pang Christiana Kartsonak yu Guo Yiping Chen Ling Yang Zheng Bian Fiona Bragg Iona Y Millwood Leijia Shen Songgen Zhou Jiben Liu Junshi Chen Liming Li Michael V Holmes Zhengming Ghen 霍永丰(译) | 2019 | 英国医学杂志中文版2019，22，1： | 6 |
| 5 | Virus-Induced Gene Silencing in the Culinary Ginger (Zingiber officinale): An Effective Mechanism for Down-Regulating Gene Expression in Tropical Monocots显示文摘导致病毒的基因 silencing (VIGS ) 被显示了有效为短暂在植物到的基因表示击倒在开发和压力相关的回答分析特定的基因的效果。VIGS 很好在 Solanaceae, Brassicaceae, Leguminaceae,和 Poaceae 以内为模型系统和庄稼的研究被建立,但是仅仅最近被用于住在这些家庭外面的植物。这里,我们证明了那个大麦条纹马赛克病毒(BSMV ) 能在 Zingiberaceae 以内感染二种,并且那 BSMVVIGS 能被用于明确地在厨房的生姜姜 officinale 的下面调整 phytoene desaturase。这些结果建议到除谷物以外的 monocots 的 BSMVVIGS 的扩展为许多重要适度、热带的庄稼种类的指导基因分析有潜力。 | Tanya Renner Jennifer Bragg Heather E. Driscoll Juliana Cho Andrew O. Jackson Chelsea D. Specht | 2009 | Molecular Plant2009，2，5： | 2 |
| 6 | 重型颅脑损伤的早期治疗(英文)显示文摘Severe traumatic brain injury remains a major health-care problem worldwide. Although major progress has been made in understanding of the pathophysiology of this injury,this has not yet led to substantial improvements in outcome. In this report,we address present knowledge and its limitations,research innovations,and clinical implications. Improved outcomes for patients with severe traumat- ic brain injury could result from progress in pharmacological and other treatments,neural repair and regeneration,optimisation of surgical indications and techniques,and combination and individually targeted treatments. Expanded classification of traumatic brain injury and in- novations in research design will underpin these advances. We are optimistic that further gains in outcome for patients with severe traumat- ic brain injury will be achieved in the next decade. | Rosenfeld JV Maas AI Bragge P Morganti-Kossmann MC Manley GT Gruen RL | 2012 | 中华神经外科疾病研究杂志2012，11，6： | 2 |
| 7 | The role of intensity-modulated radiotherapy in the treatment of parotid tumors 显示文摘 | Bragg CM Conway J Robinson MH | 2002 | int J Radiat Oncol Biol Phys2002，52，3： | 1 |
| 8 | Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS) 显示文摘 | Goodkin DA Bragg - Gresham JL Koenig KG | 2003 | J Am Soc Nephrol2003，14，12： | 1 |
| 9 | Fast analysis of volatile organic compounds and disinfection by-products in drinking water using solid-phase mieroextraetion-gas chromatography/time-of-flight mass spectrometry 显示文摘 | Niri V H Bragg L Pawliszyn J | 2008 | J Chromatogr A2008，1201，2： | 1 |
| 10 | The Contamination of Fiber Optics Connectors and Their Effect on Optical Performance显示文摘 | BERDINSKIKH T BRAGG J TSE E | 2002 | Optical Fiber Com- munication Conference and Exhibit2002，，70： | 1 |
| 11 | Influence of dietary energy source on performance and fatty liver syn- drome in White Leghorn laying hens显示文摘 | Bragg D B Sim J S Hodgson G C | 1973 | Poult Sci1973，52，2： | 1 |
| 12 | Mortality risk for patients receiving hemodiafiltration versus hemodialysis: Euro- pean results from the DOPPS 显示文摘 | Canaud B Bragg - Gresham JL Marshall MR | 2006 | Kidney Int2006，69，11： | 1 |
| 13 | An attributable cost model for a telecare system using advanced community alarms显示文摘 | Brownsell SJ Bradley DA Bragg R | 2001 | Journal of Telemedicinc and Telecare2001，，7： | 1 |
| 14 | The N-terminal 85 amino acids of the Barley stripe mosaic virus gammab pathogenesis protein contain three zinc-binding motifs显示文摘 | Bragg J N Lawrence D M Jackson A O | 2004 | Journal of Virology2004，78，14： | 1 |
| 15 | UHMWPE wear debris up-regulates mononuclear cell proinflammatory gene expression in a novel murine model of intramedullary particle disease显示文摘 | Epstein N J Bragg WE Ma T | 2005 | Acta Orthop2005，76，3： | 1 |
| 16 | The Need for Adaptive Routing in the Chaotic and Unbalanced Environment显示文摘 | Chou W Bragg A W Nilsson A A | 1981 | IEEE Transactions on Communications1981，29，4： | 1 |
| 17 | Depression as a predictor of mortality and hospitalization among hem dialysis patients in the U- nited States and Europe显示文摘 | Lopes AA Bragg J Young E | 2002 | Kidney Int2002，62，1： | 1 |
| 18 | The acute respiratory management of cervical spinal cord injury in the first 6 weeks after injury : a systematic review 显示文摘 | BERNEY S BRAGGE P GRANGER C | 2011 | Spinal Cord2011，49，1： | 1 |
| 19 | A comparison of methods, including angled and vertical minirhizotrons, for studying root growth and distribution in a spring oat crop显示文摘 | Bragg P L Govi G Canell R Q | 1983 | Plant and Soil1983，73，3： | 1 |
| 20 | Health-related quality of life and associated outcomes among hemodialysis patients of different ethuicities in the United States:the Dialysis Outcomes and Practice Patterns Study(DOPPS)显示文摘 | Lopes AA Bragg JL Satayathum S | 2003 | Am J Kidney Dis2003，41，3： | 1 |
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