|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013，2，1： | 2 |
| 2 | A single subcutaneous bolus of erythropeietin normalizes cerebral blood flow autoregulatiou after subarachnoid hemorrhage in rats显示文摘 | Spring borg JB Ma XD Rochat P | 2002 | Br J Pharmacol2002，135，： | 1 |
| 3 | Progressive rise in gut hormone levels after Rouxen-Y gastric bypass suggests gut adaptation and explains altered satiety显示文摘 | Borg CM le Roux CW Ghatei MA | 2006 | Br J Surg2006，93，2： | 1 |
| 4 | A comparison of molar root canal preparation using stainless-steel and nickel-titanium instruments显示文摘 | Carvalho LA Bonetti I Borges MA | 1999 | J Endod1999，25，12： | 1 |
| 5 | Tonin in rat heart with experimental hypertrophy显示文摘 | Borges JC Silva JA Jr Gomes MA | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 6 | Ambulatory care self-medicadon with antibiotics within countries in the south-eastern Mediterranean region: results from the ARMed project 显示文摘 | Scicluna EA Borg MA | 2007 | International Journal of Antimicrobial Agents2007，29，2： | 1 |
| 7 | Micro-biological composition associated with vitamin D receptor gene polymorphism in chronic periodontitis显示文摘 | Borges MA Figueiredo LC Brito RB Jr | 2009 | Braz Oral Res2009，23，2： | 1 |
| 8 | Tonin in rat heart with experimental hypertrophy显示文摘 | Borges JC Silva JA Jr Comes MA | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 9 | NOR sites detected by AgDAPI staining of an unusual autosome chromosome of Bradysia hygida (Diptera:Sciaridae) colocalize with C-banded heterochromatic region 显示文摘 | Gaspar VP Borges AR Fernandez MA | 2002 | Genetica2002，，114： | 1 |
| 10 | Hydrotherapy: Coadjuvant treatment to kinesiotherapy in patients with sequels after stroke 显示文摘 | Paizan NLM Silva RD Borges MA | 2009 | Rev Neurosci2009，17，4： | 1 |
| 11 | Antibiotic consumption as a driver for resistance in Staphylococcus aureus and Esche- richia coli within a developing region显示文摘 | Borg MA Zarb P Scicluna EA | 2010 | Am J Infect Con- trol2010，38，3： | 1 |
| 12 | Tonin in rat heart with experimental hypertrophy显示文摘 | Borges JC Silva JA Jr Gomes MA | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 13 | Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting显示文摘 | Borges DL Nina VJ Costa MA | 2013 | Rev Bras Cir Cardiovasc2013，28，3： | 1 |
| 14 | Biliopancreatic diversion in rats is associated with intestinal hypertrophy and with increased GLP-1, GLP-2 and PYY levels显示文摘 | Borg CM le Roux CW Ghatei MA | 2007 | Obes Surg2007，17，9： | 1 |
| 15 | Quantification of bone density of the proximal femur after hip resurfacing arthroplasty-comparison of different DXA acquisition modes显示文摘 | Hakulinen MA Borg H Hakkinen A | | 0，，04： | 1 |
| 16 | Prevalence of methicillin- resistant Staphylococcus aureus (MRSA) in invasive isolates from southern and eastern Mediterranean countries显示文摘 | Borg MA de Kraker M Scicluna E | 2007 | J Antimicrob Chemother2007，60，： | 1 |
| 17 | Evaluation of left ventricular mechanical dyssynchrony as determined by phase analysis of ECG-gated SPECT myocardial perfusion imaging in patients with left ventricular dysfunction and conduction disturbances显示文摘 | Trimble MA BorgesNeto S Smallheiser S | 2007 | J Nucl Cardiol2007，14，3： | 1 |
| 18 | Prevention of meticillin-resistant Staphylococcus aureus bloodstream infections in European hospitals:moving beyond policies显示文摘 | Borg MA Hulscher M Scicluna EA | 2014 | J Hosp Infect2014，87，4： | 1 |
| 19 | The effects of lipopolysaceharide-indueed reactive oxygen species were blunted by calcium oxalate in renal tubular epithelial cells 显示文摘 | Borges FT Garofalo AS Dalboni MA el al | 2008 | Nephron Exp Nephrol2008，108，2： | 1 |
| 20 | Polymer films with surfaces unmodified and modified by non-thermal plas- ma as new substrates for cell adhesion显示文摘 | Borges AM Benetoli LO Licinio MA | 2013 | Mater Sci Eng C Mater Biol Appl2013，33，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员