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| 1 | 舒更葡糖钠用于ASA分级Ⅲ或Ⅳ级高风险手术患者安全性的评价:随机双盲临床研究显示文摘目的评价舒更葡糖钠用于ASA分级Ⅲ或Ⅳ级高风险手术患者术后拮抗神经肌肉阻滞的安全性。尤其着重评估了心脏不良事件以及其他预先指定的临床关注不良事件的影响。方法符合ASA分级Ⅲ或Ⅳ级标准的患者,根据ASA分级和神经肌肉阻滞剂(罗库溴铵或维库溴铵)进行随机分组,新斯的明/格隆溴铵组:中度神经肌肉阻滞;舒更葡糖钠2 mg/kg组,中度神经肌肉阻滞;舒更葡糖钠4 mg/kg组,深度神经肌肉阻滞;舒更葡糖钠16 mg/kg组,深度神经肌肉阻滞(仅罗库溴铵)。主要研究终点包括治疗期间窦性心动过缓、窦性心动过速和其他心律失常的发生情况。结果344例患者进入随机化分配,331例患者接受了治疗[61%为男性,BMI(28.5±5.3)kg/m^(2),年龄(69±11)岁]。舒更葡糖钠2 mg/kg组治疗期间窦性心动过缓发生率显著降低,舒更葡糖钠2 mg/kg组和4 mg/kg组治疗期间窦性心动过速发生率显著降低(P<0.05)。4组间治疗期间其他心律失常发生率比较差异无统计学意义(P>0.05)。结论ASA分级Ⅲ或Ⅳ级高风险手术患者使用舒更葡糖钠拮抗罗库溴铵或维库溴铵诱导的中度和深度神经肌肉阻滞的安全性良好。 | W.Joseph Herring Yuki Mukai Aobo Wang Jeannine Lutkiewicz John F.Lombard Li Lin Molly Watkins David M.Broussard Manfred Blobner | 2022 | 中华麻醉学杂志2022，42，1： | 3 |
| 2 | Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients 显示文摘 | MANN R BLOBNER M JELEN-ESSELBORN S | 2000 | Anesthesiology2000，93，2： | 1 |
| 3 | Postoperativeup^er airway obstruction after recovery of the train of four ra-tio of the adductor pollicis muscle from neuromuscular block-ade 显示文摘 | Eikermann M Blobner M Groeben H | 2006 | Anesth Analg2006，102，3： | 1 |
| 4 | Point-of-care testing on admission to the intensive care unit:lactate and glucose independently predict mortality显示文摘 | Martin J Blobner M Busch R | 2013 | Clin Chem Lab Med2013，51，2： | 1 |
| 5 | Preanes- thetictrain-of-four fade predicts the atracurium equire- ment of myasthenia gravis patients显示文摘 | Mann R Blobner M Jelen-Esselborn S | 2000 | Anesthesioligy2000，93，2： | 1 |
| 6 | Clinical predictors of dura-tion of action of cisatracurium and rocuronium administered longterm 显示文摘 | Fassbender P Geldner G Blobner M | 2009 | Am J Critcare2009，18，5： | 1 |
| 7 | Postoperative upper airway obstruction after recovery of the train of four ratio of the adductor pollicis muscle from neuromuscular blockade 显示文摘 | Eikermann M Blobner M Groeben H | 2006 | Anesth Analg2006，102，3： | 1 |
| 8 | Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia:results of a randomised,controlled trial显示文摘 | Blobner M Eiksson LI Scholz J | | 0，，10： | 1 |
| 9 | Clinical predictors of duration of action of cisatracurium and rocuronium administered long-term显示文摘 | Fassbender P Geldner G Blobner M | 2009 | Am J Crit Care2009，18，5： | 1 |
| 10 | Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuroniur显示文摘 | Maybauer DM Geldner G Blobner M | | 0，，01： | 1 |
| 11 | Transport of blood gas sam- pies: is the pneumatic tube system safe? 显示文摘 | Zanner R Moser N Blobner M | 2006 | Anaesthesist2006，55，10： | 1 |
| 12 | Clinical predictors of duration of action of cisatracurium and rocuronium administered long-term显示文摘 | Fassbender P Geldner G Blobner M | 2009 | Am J Crit Care2009，18，5： | 1 |
| 13 | Transport of blood gas samples:is the pneumatic tube system safe?显示文摘 | Zanner R Moser N Blobner M | 2006 | Anaesthesi st2006，55，10： | 1 |
| 14 | Theim- pact of cardiopulmonary bypass on systemic interleukin-6 release, cerebralnuclear factor-kappa B expression, and neurocognitive outcome in rats 显示文摘 | JUNGWIRTH B ECKEL B BLOBNER M | 2010 | AnesthAnalg2010，110，2： | 1 |
| 15 | Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: Reduction in cerebral inflammation but without improvement in cognitive performance 显示文摘 | Kellermann K Dertinger N Blobner M | 2011 | J Thorae Cardiovasc Surg2011，141，4： | 1 |
| 16 | Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium 显示文摘 | aybauer DM Geldner G Blobner M | 2007 | Anaesthesia2007，62，1： | 1 |
| 17 | The impact of cardiopulmon- ary bypass on systemic interleukin-6 re- lease, cerebral nuclear factor- kappa B expression, and neuroeognitive outcome in rats 显示文摘 | Jungwirth B Eckel B Blobner M | 2010 | Anesthesia and Analge- sia2010，110，： | 1 |
| 18 | Plasma vasopress in laparoscopic cholecystectomy显示文摘 | Felber AR Blobner M Goegler S | 1993 | Anesthesiology1993，79，： | 1 |
| 19 | Clinical predictors of duration of action of cisatracufium and rocuronium administered long-term显示文摘 | FassbenderP Geldner G Blobner M etal | 2009 | AmJ Crit Care2009，18，5： | 1 |
| 20 | Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients显示文摘 | Mann R Blobner M Jelen-Esselborn S | 2000 | Anesthesiology2000，93，： | 1 |
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