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| 1 | 无需二极管的精密全波信号整流器显示文摘使用半导体二极管的整流器电路通常要处理大大超过二极管正向压降的电压,一般这不会影响整流的精度. | Jos é M Blanes Jos é A Carrasco | 2005 | 电子设计技术 EDN CHINA2005,12,12: | 2 |
| 2 | Complementary analysis of microsatellite tumor profile and mismatch repair defects in colorectal carcinomas显示文摘Microsatellite instability (MSI) is a prognostic factor and a marker of defi cient mismatch repair (MMR) in colorectal adenocarcinomas (CRC). However, a proper application of this marker requires understanding the following: (1) The MSI concept: The PCR approach must amplify the correct locus and accurately identify the microsatellite pattern in the patient’s normal tissue. MSI is demonstrat- ed when the length of DNA sequences in a tumor differs from that of nontumor tissue. Any anomalous expansion or reduction of tandem repeats results in extra-bands normally located in the expected size range (100 bp, above or below the expected product), differ from the germline pattern by some multiple of the repeating unit, and must show appropriate stutter. (2) MSI mechanisms: MMR gene inactivation (by either mutation or protein down-regulation as frequently present in deep CRC com- partments) leads to mutation accumulation in a cell with every cellular division, resulting in malignant transforma- tion. These mechanisms can express tumor progression and result in a decreased prevalence of aneuploid cells and loss of the physiologic cell kinetic correlations in the deep CRC compartments. MSI molecular mechanisms are not necessarily independent from chromosomal in- stability and may coexist in a given CRC. (3) Because of intratumoural heterogeneity, at least two samples from each CRC should be screened, preferably from the su- perfi cial (tumor cells above the muscularis propria) and deep (tumor cells infi ltrating the muscularis propria) CRC compartments to cover the topographic tumor hetero- geneity. (4) Pathologists play a critical role in identify- ing microsatellite-unstable CRC, such as occur in young patients with synchronous or metachronous tumors or with tumors showing classic histologic features. In these cases, MSI testing and/or MMR immunohistochemistry are advisable, along with gene sequencing and genetic counseling if appropriate. MSI is an excellent functional and prognostically useful marker, whereas MMR immuno- histochemistry can guide gene sequencing. | Alfredo Blanes Salvador J Diaz-Cano | 2006 | World Journal of Gastroenterology2006,12,37: | 2 |
| 3 | Elevated risk of high blood pressure: climate and the inverse housing low显示文摘 | Muchell R Blane D Barrier M | 2002 | Int J Epidemiol2002,,: | 1 |
| 4 | Natural history and familial characteristics of isolated left ventricular non-compaction 显示文摘 | Murphy RT Thaman R Blanes JG | 2005 | Eur Heart J2005,26,2: | 1 |
| 5 | A 10-year prospective study of ITI dental implants placed in the posterior region Ⅱ:influence of crown-to-implant ratio and different prosthetic treatment modalitles on crestal bone loss显示文摘 | BLANES R J BERNARD J P BLANES Z M | | 0,,06: | 1 |
| 6 | Natural history and familial characteristics of isolated left ventricular noncompaction显示文摘 | Murphy R T Thaman R Blanes J G | 2005 | Eur Heart J2005,26,2: | 1 |
| 7 | Assessment of depressive symptoms in people with diabetes mellitus and foot ulcers显示文摘 | Salom6 GM Blanes L Ferreira LM | 2011 | Rev Col Bras Cir2011,38,5: | 1 |
| 8 | Monitoring and modeling temperature variations inside silage stacks using novel wireless sensor networks显示文摘 | Green O Nadimi E S Blanes V | 2009 | Computers and Electronicsin Agriculture2009,691,: | 1 |
| 9 | Develop- ment and field test of an on-line computerized instrumenta- tion system for air velocity, temperature and differential pressure measurements in poultry houses 显示文摘 | Blanes Vidal V Guijarro E Nadimi A G | 2010 | Spanish Journal of Agricultural Research2010,8,3: | 1 |
| 10 | Multi-robot object localization:A fuzzy fusion Approach显示文摘 | Le Blane Saffiotti | 2009 | IEEE Transactions on Systems Man and Cybemetics Part B:Cyhemeties2009,39,5: | 1 |
| 11 | Differentiating walls from corners using the amplitude of ultrasonic echoes显示文摘 | Gin s Benet Milagros Martfnez Francisco Blanes | 2005 | Robotics and Autonomous Systems2005,50,1: | 1 |
| 12 | Elevated risk of high blood pressure:climate and the inverse housing law显示文摘 | Mitchell R Blane D Bartley M | 2002 | Int J Epidemiol2002,31,: | 1 |
| 13 | Assessment of depressivesymptoms in people with diabetes mellitus and foot ulcers显示文摘 | Salome GM Blanes L Ferreira LM | 2011 | Rev Col Bras Cir2011,38,5: | 1 |
| 14 | Dynamical diseases of brain systems: Different routes to epileptic seizures 显示文摘 | Da Silva F H L Blanes W Kalitzin S N | 2003 | IEEE Trans on Biomed Eng2003,50,5: | 1 |
| 15 | Hashimoto's thyroiditis shares features with early papillary thyroid carcinoma显示文摘 | Arif S Blanes A Diaz-Cano SJ | 2002 | Histopathology2002,41,4: | 1 |
| 16 | Modeling the sequential switching shunt seriesregulator 显示文摘 | GARRIGOS A CARRASCO J A BLANES J M etal | 2005 | Power Electronics Letters2005,3,1: | 1 |
| 17 | Enterocolitis associated with Hirschsprung's disease:a clinical radiologicnl characterization based on 168 patients显示文摘 | Elhalaby EA Coran AG Blane CE | | 0,,01: | 1 |
| 18 | Surface modification of polypropylene non-woven substrates by padding with antistatic agents for deposition of polyvinyl alcohol nanofiber webs by electrospinning 显示文摘 | BLANES M MARCO B G1SBERT M | 2010 | Textile Research Journal2010,80,13: | 1 |
| 19 | Health-related quality of life of primary caregivers of persons with paraplegia显示文摘 | Blanes L Carmagnani MI Ferreira LM | 2007 | Spinal Cord2007,45,6: | 1 |
| 20 | Congenital Mullerian anomalies:diagnostic accuracy of three-dimensional ultrasound显示文摘 | Raga F Bonilla-Musoles F Blanes J | 1996 | Fertil Steril1996,65,: | 1 |