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    题名 作者 年代 出处 被引量
1Mesenchymal stromal cells from human perinatal tissues: From biology to cell therapy显示文摘Cell-based regenerative medicine is of growing interest in biomedical research. The role of stem cells in this context is under intense scrutiny and may help to define principles of organ regeneration and develop innovative therapeutics for organ failure. Utilizing stem and progenitor cells for organ replacement has been conducted for many years when performing hematopoietic stem cell transplantation. Since the first successful transplantation of umbilical cord blood to treat hematological malignancies, non-hematopoietic stem and progenitor cell populations have recently been identified within umbilical cord blood and other perinatal and fetal tissues. A cell population entitled mesenchymal stromal cells (MSCs) emerged as one of the most intensely studied as it subsumes a variety of capacities: MSCs can differentiate into various subtypes of the mesodermal lineage, they secrete a large array of trophic factors suitable of recruiting endogenous repair processes and they are immunomodulatory.Focusing on perinatal tissues to isolate MSCs, we will discuss some of the challenges associated with these cell types concentrating on concepts of isolation and expansion, the comparison with cells derived from other tissue sources, regarding phenotype and differentiation capacity and finally their therapeutic potential.Karen Bieback Irena Brinkmann 2010World Journal of Stem Cells2010,2,4:15
2Critical parameters for the isolation of Mesenchymal Stem Cells from umbilical cord blood显示文摘Karen Bieback Susanne Kern Harald Klter 2004Stem Cells2004,22,4:1
3Comparing mesenehymal stromal cells from different human tissues: bone marrow, adipose tissue and umbilical cord blood显示文摘Bieback K Kern S Kocaomer A 2008Biomed Mater Eng2008,18,1:1
4Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood显示文摘Karen Bieback K Kern S Kluter H 2004Stem Cells2004,22,4:1
5Mesenchymal stromal cells from umbilical cord blood显示文摘Bieback K Kltlter H 2007Curr Stem Cell Res Ther2007,2,4:1
6Comparing mesenchymal stromal cells from different human tissues: bone marrow, adipose tissue and umbilical cord blood 显示文摘Bieback K Kern S Kocaomer A 2008Biomed Mater Eng2008,18,1:1
7Hermann Eichler Critical Parameters for the isolation of Mesenchymal Stem Cells from Umbilical Cord Blood显示文摘Karen Bieback Susanne Kem Hamld K1ter 2004Stem Cells2004,22,4:1
8Critical parameters for the isolation of mesenchymal stem cell from umbilical eord blood显示文摘Bieback K Kern S Kluter H 2004Stem Cells2004,22,9:1
9Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood显示文摘 Kern S Kluter H 2004Stem Cells2004,22,4:1
10Human alternatives tofetal bovine serum for the expansion of mesenchymal stromal cellsfrom bone marrow 显示文摘Bieback K Hecker A KocaomerA 2009Stem Cells2009,27,9:1
11In-vitro analysis of the expressionof TGF beta-superfamily-members during chondrogenic differentiation of mesenchymal stem cells and chondrocytes during dedifferentiation in cell culture 显示文摘Ooesslerur Bugert P Bieback K 2005Cell Mol Biol Lett2005,10,2:1
12H uman alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow显示文摘Bieback K Hecker A Koca(o)mer A 2009Stem Cells2009,27,9:1
13Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood显示文摘Bieback K Ken S Kluter H 0,,:1
14In-vitro analysis of the expression of TGFbeta-superfamily-members during chondrogenic differentiation of mesenchymal stem cells and chondrocytes during dedifferentiation in cell culture显示文摘Goessler UR Bugert P Bieback K 2005Cell Mol Biol Lett2005,10,2:1
15Mesenchymal stem cells and cardiac repair 显示文摘Nesselmann C Ma N Bieback K 2008J Cell Mol Med2008,12,5:1
16Hemagglutinin protein of wild - type measles virus activates toil - like receptor 2 signaling 显示文摘Bieback K Lien E Klagge IM 2002J Virology2002,976,17:1
17In vitro analysis of the expression of TGF beta superfamily members during ehondrogenic differentiation of mesenchymal stem cells and chondrocytes during dedifferentiation in cell culture显示文摘Goessler UR Bugert P Bieback K 2005Cell Mol Biol Lett2005,10,2:1
18Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood显示文摘Bieback K Kern S Kluter H 2004Stem Cells2004,22,:1
19In vitro analysis of the expression of TGFbeta superfamily members during chondrogenic differentiation of mesenchymal stem cells and chondrocytes during dedifferentiation in cell culture显示文摘GOESSLER U R BUGERT P BIEBACK K 2005Cell Mol Biol Lett2005,10,2:1
20Critical parameters for the isolation of mesenchymal stem ceils from umbilical cord blood 显示文摘BIEBACK K KERN S KLUTER H 2004Stem Ceils2004,22,4:1
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