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146篇 您的检索式:作者名="Bhullar"
    题名 作者 年代 出处 被引量
1Animal models of human colorectal cancer:Current status, uses and limitations显示文摘AIM: To make orthotopic colon cancer murine modelsa more clearly understood subject. The orthotopic tumor models have been found to be more relevant in replicating the human disease process as compared to heterotopic models, many techniques for making orthotopic colorectal murine models have been reported.METHODS: We evaluated the current literature for various reported orthotopic colon cancer models to understand their techniques, advantages and limitations. An extensive literature review was performed by searching the National Library of Medicine Database(Pub Med) using Me SH terms animal model; colon cancer; orthotopic model; murine model. Twenty studies related to colon cancer orthotopic xenograft model were evaluated in detail and discussed here. RESULTS: The detailed analysis of all relevant reports on orthotopic model showed tumor take rate between 42%-100%. While models using the enema technique and minimally invasive technique have reported development of tumor from mucosa with tumor take rate between 87%-100% with metastasis in 76%-90%.CONCLUSION: Over the years, the increased understanding of the murine models of human colon cancer has resulted in the development of various models. Each reported model has some limitations. These latest models have opened up new doors for continuing cancer research for not only understanding the colon cancer pathogenesis but also aid in the development of newer chemotherapeutic drugs as they mimic the human disease closely.Vijay K Mittal Jasneet Singh Bhullar Kumar Jayant 2015World Journal of Gastroenterology2015,21,41:5
2Curcumin and its carboeyelie analogs: structure-activity in relation to antioxidant and selected biological properties显示文摘BHULLAR S JHA A YOUSSEF D 2013Molecules2013,18,5:1
3Single-incision laparoscopic cholecystectomy(SILC)using non-articulating instruments and conventional trocars-single surgeon experience显示文摘Chaudhary S Bhullar JS Subhas G 2013J Gastrointest Surg2013,17,4:1
4Effects of ingredients supplementation on textural characteristics and microstructure of yoghurt显示文摘BHULLAR Y S UDDIN M A 2002Milehwissen- sclmft2002,57,6:1
5Self- assembling protein microarrays 显示文摘Ramachandran N Hainsworth E Bhullar B 2004Science2004,305,:1
6Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure显示文摘 Bhullar VB Workowski KA 2000J Infect Dis2000,181,:1
7Dating reservoir filling-a case history from the North Sea显示文摘Bhullar A G 1999Marine and Petroleum Geology1999,16,3:1
8Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells 显示文摘Singh N Chakraborty R Bhullar RP 2014Biochem Biophys Res Commun2014,446,2:1
9Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure显示文摘Somani J Bhullar VB Workowski KA 2000J Infect Dis2000,181,:1
10Treatment of an open me- dial tibiotalar dislocation with no associated fracture显示文摘Bhullar PS Grant DR Foreman M ct al 2014J Foot Ankle Surg2014,53,6:1
11Linker-assisted immunoassay and liquid chromatography/mass spectrometry for the analysis of glyphosate 显示文摘Lee E A Zimmerman L R Bhullar B S 2002Anal Chem2002,74,:1
12YBX1 expression and function in early hematopoiesis and leukemic cells显示文摘Bhullar J Sollars VE 2011I mmunogeneties2011,63,6:1
13Strategies for Implementing AdvancedProcess Controls in a Distributed Control System (DCS)显示文摘Bhullar Romel S 1993ISATransactions1993,32,2:1
14Methane transport and emissions from soil as affected by water table and vascular plants显示文摘BHULLAR G S IRAVANI M EDWARDS P J 2013BMC Ecology2013,13,1:1
15Selective nonoperative management of blunt splenic injury:an Eastern Association for the Surgery of Trauma practice management guideline显示文摘Stassen N A Bhullar I Cheng J D 2012J Trauma Acute Care Surg2012,,54:1
16An Evaluation of the THIN Database in the OMOP Common Data Model for Active Drug Safety Surveillance显示文摘Xiaofeng Zhou Sundaresan Murugesan Harshvinder Bhullar 2013Drug Saf2013,36,2:1
17Self- assembling protein microarrays 显示文摘Ramachandran N Hainsworth E Bhullar B 2004Science2004,305,5680:1
18Differential responses to high temperatures of starch and nitrogen accumulation in the grain of four cultivars of wheat显示文摘Bhullar S S Jenner C F 1985Australian Journal of Plant Physiology1985,12,:1
19Lifespan and heahhspan extension by resveratrol显示文摘BHULLAR K S HUBBARD B P 2015Biochim Biophys Acta2015,1852,6:1
20Multipledrug-resistant associatedwith clinical treatment failure显示文摘Somani J Bhullar VB Workowski KA 2000J Infect Dis2000,181,14:1
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