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| 1 | 急性脑梗死静脉溶栓治疗中凝血相关指标变化显示文摘目的:探讨纤维蛋白原、纤维蛋白降解产物、D-二聚体等凝血相关指标在急性缺血性脑卒中(AIS)静脉溶栓前后的改变。方法:选择80例发病后7h静脉内溶栓的急性大脑中动脉供血区AIS病例,观察溶栓前、溶栓后2h、溶栓后24h的凝血相关指标变化。结果:在AIS溶栓治疗中,纤维蛋白原在溶栓后2h较溶栓前降低(P<0.01),溶栓24h后上升(P<0.01),但仍低于溶栓前水平(P<0.05);纤维蛋白溶解产物在溶栓后2h较溶栓前升高(P<0.01),溶栓24h后下降(P<0.01);D-二聚体在溶栓后2h较溶栓前升高(P<0.01),溶栓24h后降低(P<0.01),但仍高于溶栓前(P<0.01);ⅩⅢ因子水平在溶栓24h后明显下降(P<0.01);α2-抗纤溶酶水平在溶栓后2h较溶栓前下降(P<0.01),溶栓24h后上升(P<0.01),但仍低于溶栓前水平(P<0.01);纤溶酶原水平在溶栓后2h较溶栓前下降(P<0.01),溶栓24h后上升(P<0.01),但仍低于溶栓前水平(P<0.01);血小板在溶栓治疗后低于溶栓前,尤其是溶栓24h后(P<0.05)。结论:在AIS溶栓治疗中,纤维蛋白原、ⅩⅢ因子、α2-抗纤溶酶、纤维蛋白溶解酶原、D-二聚体、纤维蛋白降解产物及血小板都发生明显变化,与纤溶作用机制相符。 | 孙旭红 Paul Trouillas Miche Berthiller Michel Hanss 李威 翟宇 | 2011 | 中国临床神经科学2011，19，5： | 6 |
| 2 | 全球食品和饲料链中生物毒素早期预警、监测和毒性评估的挑战和解决方案显示文摘确保世界人口不断增长下的食品供应安全和保障是巨大和紧迫的需求。然而,全球农业和食品行业仍易受植物、藻类,尤其是真菌产生的生物毒素污染问题的挑战;随着全球变暖和极端天气事件频发,这些有毒代谢产物的发生愈发难以预测。为了提升食品和饲料链中生物毒素的预警、监测和毒性评估方法,总结在各个科学领域和方法中创新所需的多学科、多部门互补能力,具体包括使用卫星和无人机成像的大数据方法、便携式监测设备以及使用蛋白质组学和转录组学对(新兴)生物毒素进行(联合)毒性测试。 | Rudolf Krska Eskola Mari Berthiller Franz Nielen Michel Oswald Isabelle Elliott Chris McNerney Oonagh BotanaLuis Miguel MalachováAlexandra | 2021 | 粮油食品科技2021，29，6： | 2 |
| 3 | Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize显示文摘 | SULYOK M BERTHILLER F KRSKA R | 2006 | Rapid Commun Mass Spectrom2006，20，： | 1 |
| 4 | Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize 显示文摘 | SULYOK M BERTHILLER F KRSKA R | 2006 | Rapid Commun Mass Spectr~ m2006，20，18： | 1 |
| 5 | Rapid simultaneous determination of major type A and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatographytandem mass spectrometry显示文摘 | Berthiller F Sehuhmacher R Buttinger G | 2005 | Journal of Chromato- graphy A2005，1062，2： | 1 |
| 6 | Word fragments and repeats in spontaneous spoken French 显示文摘 | Sandrine Henry& Berthille Pallaud | 2003 | Theoretical Linguistics2003，，90： | 1 |
| 7 | Development and validation ofa liquid chromatography/tandem mass spectrometric method forthe determination of 39 mycotoxins in wheat and maize显示文摘 | Sulyok M Berthiller F Krska R | 2006 | RapidCommun Mass Spectrom2006，20，18： | 1 |
| 8 | Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP- glucosyltransferase from Arabidopsis thaliana显示文摘 | POPPENBERGER B BERTHILLER F LUCYSHYN D | 2003 | Journal of Biological Chemistry2003，278，47： | 1 |
| 9 | Survey of deoxynivalenol and its conjugates deoxynivalenol-3-glucoside and 3-acetyl-deoxynivalenol in 374 beer samples显示文摘 | Elisabeth Varga Alexandra Malachova Heidi Schwartz Rudolf Krska Franz Berthiller | 2013 | Food Additives & Contaminants: Part A2013，，1： | 1 |
| 10 | Hydrolytic fate of deoxynivalenol-3-glucoside during digestion显示文摘 | Franz Berthiller Rudolf Krska Konrad J. Domig Wolfgang Kneifel Nathalie Juge Rainer Schuhmacher Gerhard Adam | 2011 | Toxicology Letters2011，，3： | 1 |
| 11 | Developments in mycotoxin analysis:an update for 2009-2010显示文摘 | Shephard G S Berthiller F Burdaspal P | 2011 | World Mycotoxin Journal2011，4，1： | 1 |
| 12 | Rapid simultaneous de-termination of major type A-and B-trichothecenes as well as zearalenone inmaize by high performance liquid chromatography-tandem mass spectrometry显示文摘 | Berthiller F Schuhmacher R Buttinger G | 2005 | J Chromatogr A2005，1062，20： | 1 |
| 13 | The ability to detoxify the mycotoxin deoxynivalenol colocalizes with a major quanti tative trait locus for Fusarium head blight resistance in wheat 显示文摘 | Lemmens M Scholz U Berthiller F | 2005 | Molecular Plant-microbe Interactions2005，181，： | 1 |
| 14 | Rapid simultaneous determination of major type A and B-tricho-thecenes as well as Zearalenone in maize by high performance liquid chromatography-Tandem mass spectrometry显示文摘 | Berthiller F Schuhmacher R Buttinger G | 2005 | J Chromatogr A2005，1062，： | 1 |
| 15 | Rapid simultane- ous determination of major type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography- tandem mass spectrometry显示文摘 | Berthiller F Schuhmacher R Buttinger G | 2005 | J Chromatogr A2005，1062，2： | 1 |
| 16 | Simultaneous de- termination of type A - & B-trichothecenes and zearalenone in ce- reals by High Performance Liquid Chromatography - Tandem Mass Spectrometry 显示文摘 | Schuhmacher R Berthiller F Buttinger G | 2005 | Mycotoxin Res2005，21，4： | 1 |
| 17 | Sexual behaviours and the risk of head and neck cancers:a pooled analysis in thee International Head and Neck Cancer Epidemiology (INHANCE)consortium显示文摘 | Heck JE Berthiller J Vaccarella S | | 0，，： | 1 |
| 18 | Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize 显示文摘 | Sulyok M Berthiller F Krska R | 2006 | Rapid Commun Mass Spectrom2006，20，18： | 1 |
| 19 | Rapid simultaneous determination of major type A-and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry显示文摘 | Berthiller F Schuhmacher R Buttinger G | | 0，，02： | 1 |
| 20 | Detoxification of the Fusarium my(c)otoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana显示文摘 | POPPENBERGER B BERTHILLER F LUCYSHYN D | 2003 | J Biol Chem2003，278，47： | 1 |
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