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2篇 您的检索式：作者名="Bernard Robaye"

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		题名	作者	年代	出处	被引量
	1	Role of the P2Y<sub>13</sub> Receptor in the Differentiation of Bone Marrow Stromal Cells into Osteoblasts and Adipocytes显示文摘	Galadrielle Biver Ning Wang Alison Gartland Isabel Orriss Timothy R. Arnett Jean‐Marie Boeynaems Bernard Robaye	2013	Stem Cells2013，，12：	1
	2	Role of the P2Y6 receptor of UDP in the modulation of murine dendritic cell functions and Th1 polarisation of the immune response显示文摘Numerous studies have demonstrated the role of uridine diphosphate(UDP)and its P2Y6 receptor in the inflammatory reaction and innate immunity.However,the importance of the P2Y6 receptor in the adaptive immune response remains unclear.In this study,we demonstrate that the P2Y6 receptor is functionally expressed in murine bone marrow dendritic cells(BMDC).UDP induced a Ca^2+transient in these cells that was decreased in P2Y6-deficient mice.UDP also increased the endocytosis of fluorescein isothiocyanate-dextran(FITC-dextran)and amplified the secretion of interleukin 12-p70(IL-12p70)induced by CpG;these responses were abolished in P2Y6-deficient mice.In vivo experiments showed that the serum level of specific IgG2c after immunisation with ovalbumin was decreased in P2Y6-deficient mice,while the level of specific IgG1 was unchanged.These data suggest that the P2Y6-mediated effects of UDP on myeloid dendritic cells play a role in the in vivo Th1 skewing of the immune response.	Dorothée Cammarata Abduelhakem Ben Addi Eva D’Amico Bernard Robaye 无	2016	Journal of Medicines Development Sciences2016，2，1：	0

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