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    题名 作者 年代 出处 被引量
1山东日照地区系统区域调查的新收获显示文摘1995年以来,山东大学和美国耶鲁大学、芝加哥自然历史博物馆等单位合作,在山东日照地区开展了长期的系统区域调查,取得丰硕成果,并在探索适合中国实际的田野考古方法上获得重要经验。本文概略介绍了这一研究课题的调查区域、调查目的和采用的方法,并对前5年的调查成果进行了初步的归纳和总结。方辉 栾丰实 于海广 蔡凤书 Anne Underhill Gary Feinman Linda Nicholas Gwen Bennet 2002考古2002,,5:22
2Can we further optimize therapeutic hypothermia for hypoxic-ischemic encephalopathy?显示文摘Perinatal hypoxic-ischemic encephalopathy is a leading cause of neonatal death and disability.Therapeutic hypothermia significantly reduces death and major disability associated with hypoxic-ischemic encephalopathy;however,many infants still experience lifelong disabilities to movement,sensation and cognition.Clinical guidelines,based on strong clinical and preclinical evidence,recommend therapeutic hypothermia should be started within 6 hours of birth and continued for a period of 72 hours,with a target brain temperature of 33.5 ±0.5℃ for infants with moderate to severe hypoxic-ischemic encephalopathy.The clinical guidelines also recommend that infants be re warmed at a rate of 0.5℃ per hour,but this is not based on strong evidence.There are no randomized controlled trials investigating the optimal rate of rewarming after therapeutic hypothermia for infants with hypoxic-ischemic encephalopathy.Preclinical studies of rewarming are conflicting and results were confounded by treatment with sub-optimal durations of hypothermia.In this review,we evaluate the evidence for the optimal start time,duration and depth of hypothermia,and whether the rate of rewarming after treatment affects brain injury and neurological outcomes.Anthony Davies Guido Wassink Laura Bennet Alistair J.Gunn Joanne O.Davidson 2019Neural Regeneration Research2019,14,10:20
3半再生重整分子水平反应动力学模型显示文摘根据实验数据建立了半再生重整分子水平反应动力学模型。模型包括305个C1-C12分子组分及864个化学反应,其中包括数十种烯烃及C6-C9所有芳烃异构体的生成与转化。以Langmuir-Hinshelwood-Hougen-Watson(LHHW)方程模拟反应速率,采用线性自由能关联方法(LFER)获取动力学参数,利用实验数据对模型进行了校正及检验。结果表明,芳烃脱烷基速率较低,应区分于加氢裂化反应;芳烃甲基迁移速率不容忽视,对C8+芳烃产物分布有影响;模型对贫、富芳烃2种原料在10组不同反应条件下的C5+液收、正构烷烃和环烷烃产率的预测较为准确,对C6-C9芳烃组分产率(质量分数)的预测偏差平均值小于3%。周祥 王杰广 侯震 BENNET Craing A 马爱增 KLEIN Michael T 郭锦标 2016石油学报(石油加工)2016,32,4:5
4胃癌组织Ⅱ型β转化生长因子受体基因突变的研究显示文摘目的 β转化生长因子 ( transforming growth factorβ,TGF- β) 型受体 TGF- βR 基因突变是某些肿瘤细胞逃逸 TGF- β生长抑制调控的机制之一。有报道表明 TGF- βR 基因的两个突变热点 ( c DNA70 9- 718,1931- 1936)在人类结肠癌细胞系有高的突变率。据此我们检测了 TGF- βR 基因这两个热点在 4 4例人胃癌组织的改变。方法 组织 DNA提取后进行 PCR- SSCP银染分析 ,将阳性标本进行荧光测序。结果 在 TGF- β R 的 c DNA70 9- 718位点突变率为 6.8% ( 3/ 4 4 ) ,而另一位点 c DNA1931- 1936未发现突变 ( 0 / 4 4 )。结论 TGF- β R 基因在人胃癌组织较之结肠癌具有低的突变率。柯杨 K Hagiwara 苏秀兰 冯莉雅 张建明 王永信 WP Bennet 1997中华肿瘤杂志1997,19,1:3
5QT prolongation is associated with increased mortality in end stage liver disease显示文摘AIM To determine the prevalence of QT prolongation in a large series of end stage liver disease(ESLD) patients and its association to clinical variables and mortality.METHODS The QT interval was measured and corrected for heart rate for each patient,with a prolonged QT cutoff defined as QT > 450 ms for males and QT > 470 ms for females.Multiple clinical variables were evaluated including sex,age,serum sodium,international normalized ratio,creatinine,total bilirubin,beta-blocker use,Model for EndStage Liver Disease(MELD),MELD-Na,and etiology of liver disease. RESULTS Among 406 ESLD patients analyzed,207(51.0%) had QT prolongation. The only clinical variable associated with QT prolongation was male gender(OR = 3.04,95%CI:2.01-4.60,P < 0.001). During the study period,187patients(46.1%) died. QT prolongation was a significant independent predictor of mortality(OR = 1.69,95%CI:1.03-2.77,P = 0.039). In addition,mortality was also associated with viral etiology of ESLD,elevated MELD score and its components(P < 0.05 for all). No significant reversibility in the QT interval was seen after liver transplantation. CONCLUSION QT prolongation was commonly encountered in an ESLD population,especially in males,and served as a strong independent marker for increased mortality in ESLD patients.Sun Moon Kim Bennet George Diego Alcivar-Franco Charles L Campbell Richard Charnigo Brian Delisle Jonathan Hundley Yousef Darrat Gustavo Morales Samy-Claude Elayi Alison L Bailey 2017World Journal of Cardiology2017,9,4:3
6植物钾营养高效与膜转运系统的关系(英文)显示文摘HKT1和HAK1等转运子介导钾离子的高亲和吸收以及K+/Na+共运转 ,从而可能增强Na+替代K+的能力 ;KAT1和KST1等离子通道介导钾离子的累积和转运 ,从而调节气孔细胞的渗透压 ,控制气孔运动。阐述了植物生物膜上离子转运机制和钾营养高效机理的某种可能的关系。刘建祥 杨肖娥 吴良欢 John Bennet 2001植物学通报2001,18,5:3
7选择性头部降温对胎羊缺血性脑损伤纹状体神经元凋亡和星形胶质细胞增殖的影响显示文摘目的研究选择性头部降温对缺血性脑损伤胎羊纹状体神经元凋亡和星形胶质细胞增殖的影响。方法胎羊于妊娠117~124d时通过双侧颈动脉阻塞30min造成双侧脑缺血损伤,损伤后将胎羊随机分为:损伤组(n=10)、2h低温组(损伤后2h开始亚低温治疗,n=7)和6h低温组(损伤后6h开始亚低温治疗,n=8),另设正常对照组(n=5)。通过冷循环水进行选择性头部降温,取脑组织用免疫组化法检测胎羊纹状体caspase-3(半胱天冬氨酸酶-3),GFAP(胶质纤维酸性蛋白)和PCNA(增殖细胞核抗原)的表达。结果①纹状体神经元凋亡:正常对照组中,caspase-3表达极少(11.00±13.77),损伤组caspase-3免疫阳性细胞为177.70±48.69,明显增加(P=0.000),损伤后2h治疗组(54.14±39.44,P=0.000)和损伤后6h治疗组(122.43±52.36,P=0.017)均能减少caspase-3免疫阳性细胞。②纹状体星形胶质细胞增殖:与正常对照组(163.40±21.98)相比,缺血性脑损伤组的GFAP免疫阳性细胞明显增多(433.25±66.69,P=0.000),损伤后2h开始亚低温治疗(219.50±35.31,P=0.000)和损伤后6h开始亚低温治疗(272.50±86.20,P=0.000)均能减少GFAP免疫阳性细胞。③纹状体PCNA阳性细胞的表达:在正常对照组中,PCNA免疫阳性细胞较少,为153.40±12.46,缺血性脑损伤组的PCNA免疫阳性细胞明显增多(353.70±45.60,P=0.000),损伤后2h开始亚低温治疗(187.14±26.26,P=0.000)和损伤后6h开始亚低温治疗(230.25±67.46,P=0.000)均能减少PCNA免疫阳性细胞。结论亚低温可以抑制纹状体神经元的凋亡和星形胶质细胞的增殖,该作用可能为选择性头部降温的脑保护作用机制之一。骆菲 曹云 Guan J Gunn AJ Bennet L George S Gluckman PD 杨毅 陈莲 2007复旦学报(医学版)2007,34,4:2
8Apoptosis of human vascular smooth muscle cells derived from normal vessels couonary atheresclerotic plaques 显示文摘Bennet M Evan G Schwartz S 1995Clin invest1995,95,5:1
9Deregulated c-myc oncogene expression blocks vascular smooth muscle cell inhibition mediated by heparin,interferon-gamma,mitogen depletion and cyclic nucleotide analogues and induces apoptotic cell death显示文摘Bennet MR Evan GI Newby AC 1994Circulation Res1994,,:1
10Bundling a new identified risk factor for neonatal tetanus 显示文摘Bennet J 1996IntJEpidemiol1996,25,4:1
11Interleukin 10 (IL - 10) inhibits cytokine synthesis by human monocytes:An autoregulatory role of IL- 10 produced by monocytes显示文摘Rene de Waal Malefyt Jhon Abrams Bruce Bennet 1991Exp Med1991,174,11:1
1225- Norhopanes: formation during biodegradation of petrole- um in the subsurface 显示文摘BENNET B FUSTIC M FARRIMOND P 2006Organic Geochemistry2006,37,7:1
13Lp(a) level and risk of future coronary heart disease: large scale prospective date 显示文摘Bennet A Di Angelantonio E Erqou S 2008Arch Intern Med2008,168,6:1
14Distributed control of multirobot systems using bifurcating potential fields显示文摘BENNET D J MCINNES C R 2010Robotics and Autonomous Systems2010,58,3:1
15Mechanisms of hypotherrn neuroprotection显示文摘Drury PP Bennet L Gunn AJ 2010Semin Fetal Neonatal Med2010,1,:1
16Comparison of three priming techniques for onion seed lots differing in initial seed quality显示文摘Caseiro R Bennet M A Marcos-Filho 2004Seed Science and Technology2004,32,:1
17The Italian industrial districts and the crisis of the cooperative form: part I, part II 显示文摘Harrison Bennet 1994European Planning Studies1994,2,1:1
18Photochemical properties of porphrin; an agent for use in tumor phototherapy显示文摘Ghiggino KP Bennet LE henderson RW 1998Photochem Photobiol1998,47,:1
19Treatment of ulcerative colitis by implantation of normal colonic flora 显示文摘Bennet JD Brinkman M 1989Lancet1989,1,8630:1
20Isolated human islets trigger an instant blood mediated inflammatory reac- tion: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes 显示文摘Bennet W Groth CG Larsson R 2000Upsala J Med Sci2000,105,2:1
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