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1篇 您的检索式:作者名="Benjamin Crawshaw"
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1Do the benefits outweigh the side effects of colorectal cancer surveillance? A systematic review显示文摘Most patients treated with curative intent for colorectal cancer(CRC) are included in a follow-up program involving periodic evaluations. The survival benefits of a follow-up program are well delineated, and previous meta-analyses have suggested an overall survival improvement of 5%-10% by intensive follow-up. However, in a recent randomized trial, there was no survival benefit when a minimal vs an intensive follow-up program was compared. Less is known about the potential side effects of follow-up. Well-known side effects of preventive programs are those of somatic complications caused by testing, negative psychological conse-quences of follow-up itself, and the downstream impact of false positive or false negative tests. Accordingly, the potential survival benefits of CRC follow-up must be weighed against these potential negatives. The present review compares the benefits and side effects of CRC follow-up, and we propose future areas for research.Knut Magne Augestad Johnie Rose Benjamin Crawshaw Gregory Cooper Conor Delaney 2014World Journal of Gastrointestinal Oncology2014,6,5:0
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