|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Parental transmission of type 2 diabetes mellitus in a highly endogamous population显示文摘AIM: To determine the parental transmission of diabetes mellitus (DM) and evaluate its influence on the clinical characteristics. METHODS: This was a cross sectional study. The survey was carried out in urban and semi-urban primary health care centers. Of the 2400 registered with diagnosed diabetes, 1980 agreed and gave their consent to take part in this study, thus giving a response rate of 82.5%. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. DM was defined according to the World Health Organization expert group. A trained nurse performedphysical examinations and measurements. RESULTS: Of the study population, 72.9% reported a family history of DM. Family history of DM was significantly higher in females (54.2%; P = 0.04) and in the age group below 30 years (24%; P < 0.001). The prevalence of diabetes was higher among patients with a diabetic mother (25.4% vs 22.1%) and maternal aunts/uncles (31.2% vs 22.2%) compared to patients with a diabetic father and paternal aunts/ uncles. Family history of DM was higher in patients of consanguineous parents (38.5%) than those of non-consanguineous parents (30.2%). The development of type 2 diabetes mellitus (T2DM) complications was higher in patients with either a paternal or maternal history of DM than in those without. No significant difference was observed in the metabolic characteristics of patients with/without family history of DM except for hypertension. Complications were higher in diabetic patients with a family history of DM. CONCLUSION: The present study found a significant maternal effect in transmission of T2DM. Family history is associated with the increased incidence of diabetes. | Abdulbari Bener Mohammad T Yousafzai Abdulla OAA Al-Hamaq Abdul-Ghani Mohammad Ralph A DeFronzo | 2013 | World Journal of Diabetes2013，4，2： | 28 |
| 2 | Driver sleepiness,fatigue,careless behavior and risk of motor vehicle crash and injury:Population based case and control study显示文摘Background: A few studies have been conducted to determine the relationship between road motor vehicle crashes(MVC) and serious injuries related to tiredness, fatigues and sleeping.Aim: To determine the effects of aggressive behaviour, driver sleepiness and fatigue on MVC and related injuries among Turkish population.Design and setting: Population-based case and control study conducted at the accident emergency departments of hospitals and roads.Subjects: 515 car drivers involved in crashes with injury were admitted to hospital and 1030 car drivers involved while driving on public roads as control group during the study period.Methods: The Manchester driver behaviour questionnaire(DBQ) measured the aberrant driving behaviours leading to accidents. Participants completed a fatigue severity scale(FSS) and Stanford Sleeping questionnaire an epworth scale with items related to sociodemographic information, driving experiences, adherence to traffic laws(such as speed limits and seat belt), and drivers' driving records.Results: In a representative sampling, participant's age ranged from 25 to 65 and the mean and standard deviation were 36.5 ± 7.8 for cases and 37.0 ± 8.0 for controls. There was a significant difference in both group of drivers regarding BMI, level of education, marital status, driving experience, seat belt use, excessive speed limits, physical activity number of sleeping hours, mobile phone use, and cigarette smoking habit(p = 0.017). Also, there was a significant higher mean score on all the DBQ violation questions among case group in comparison with the control group(p < 0.001). Further, cases had higher prevalence of Epworth sleeping disorders(p < 0.001) and fatigue severity(p = 0.003) compared to control drivers. Multivariate logistic regression revealed that excessive speed, fatigue, lapses, errors, Stanford sleepiness score, violations, mobile phone use and Epworth sleepiness scale were significantly associated with injury involvement in vehicle crash, after adjusting for driving experience and annual mileage.Conclusion: The current study confirmed that drivers with chronic fatigue, acute sleepiness,and careless driver behavior may significantly increases the risk of road crash which can be lead to serious injury. | Abdulbari Bener Erol Yildirim Turker Ozkan Timo Lajunen | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，5： | 5 |
| 3 | Association between psychological distress and gastrointestinal symptoms in diabetes mellitus显示文摘AIM:To examine the possible association between gastrointestinal symptoms and anxiety and depression in type 2 diabetes mellitus(T2DM).METHODS:The study was a matched case-control study based on a face to face interview with designed diagnostic screening questionnaires for gastrointestinal(GI) symptoms and T2DM,Patient Health Questionnaire(PHQ-9) for depression and General Anxiety Disorders(GAD-7) for anxiety.The questionnaire consisted of questions about symptoms and signs of anxiety and depression disorders.Also,socio-demographic characteristics,life style habits and the family history of patients were collected.It was carried out from June 2010 to May 2011 among Qatari and other Arab nationals over 20 years of age at Primary Health Care Centers of the Supreme Council of Health,Qatar,including patients with diabetes mellitus and healthy subjects over 20 years of age.RESULTS:In the studied sample,most of the studied T2DM patients with GI symptoms(39.3%) and healthy subjects(33.3%) were in the age group 45-54 years(P < 0.001).The prevalence of severe depression(9.5% vs 4.4%,P < 0.001) and anxiety(26.3% vs 13.7%,P < 0.001) was significantly higher in T2DM patients with GI symptoms than in general population.Obesity(35.7% vs 31.2%) and being overweight(47.9% vs 42.8%) were significantly higher in T2DM patients with GI symptoms than in healthy subjects(P = 0.001).Mental health severity score was higher in T2DM patients with GI symptoms than in healthy subjects;depression(8.2 ± 3.7 vs 6.0 ± 3.6) and anxiety(7.6 ± 3.3 vs 6.0 ± 3.7).The most significant GI symptom which was considerably different from controls was early satiety [odds ratio(OR) = 10.8,P = 0.009] in depressed T2DM patients and loose/watery stools(OR = 2.79,P = 0.029) for severe anxiety.Anxiety was observed more than depression in T2DM patients with GI symptoms.CONCLUSION:Gastrointestinal symptoms were significantly associated with depression and anxiety in T2DM patients,especially anxiety disorders. | Abdulbari Bener Suhaila Ghuloum Abdulla OAA Al-Hamaq Elnour E Dafeeah | 2012 | World Journal of Diabetes2012，3，6： | 5 |
| 4 | Treatment of hepatitis C virus genotype 4 with peginterferon alfa-2a: Impact of bilharziasis and fibrosis stage显示文摘AIM: To evaluate pegylated interferon alpha2a (PegIFN- α2a) in Egyptian patients with HCV genotype 4, and the impact of pretreatment viral load, co-existent bilharziasis and histological liver changes on response rate. METHODS: A total of 73 na?ve patients (61 with history of bilharziasis) with compensated chronic HCV genotype 4 were enrolled into: group A (38 patients) who received 180 mg PegIFN-alpha2a subcutaneously once weekly for a year and group B (35 patients) received IFN alpha-2a 3 MU 3 times weekly. Ribavirin was added to each regimen at a dose of 1200 mg. Patients were followed for 72 wk and sustained response was assessed. RESULTS: Significant improvement in both end of treatment response (ETR) (P < 0.002) and sustained response (SR) (P < 0.05) was noted with pegylated interferon, where ETR was achieved in 29 (76.3%) and 14 patients (40%) in both groups respectively, and 25 patients in group A (65.8%) and 9 (25.7%) in group B could retain negative viraemia by the end of follow up period. Sustained virological response (SVR) showed a significant negative correlation with age and positive correlation with pretreatment inflammation in patients receiving PegIFN. Viral clearance after 3 mo of therapy was associated with high incidence of ETR and SR (P < 0.001), but without significant difference between both forms of interferon. Significant improvement in response was achieved in patients with high grade fibrosis (grade 3 and 4) with PegIFN-α2a, where SR was seen in 5 out of 13 patients in group A, but none in group B. There was no significant difference in response betweenbilharzial and non-bilharzial patients in both groups. In terms of safety and tolerability, neutropenia was the predominant side effect; both drugs were comparable. CONCLUSION: PegIFN-α2a combined with ribavirin results in improvement in sustained response in HCV genotype 4, irrespective of history of bilharzial infestation. | MF Derbala SR Al Kaabi NZ El Dweik F Pasic MT Butt R Yakoob A Al-Marri AM Amer N Morad A Bener | 2006 | World Journal of Gastroenterology2006，12，35： | 3 |
| 5 | Prevalence and Impact of Diabetes Mellitus in Patients With Acute Myocardial Infarction:A 10-year Experience显示文摘 | El-Menyar AA Albinali HA Bener A | 2009 | Angiology2009，60，6： | 1 |
| 6 | Analysis of naive Bayes' assumptions on software fault data: an empirical study显示文摘 | TURHAN B BENER A | 2009 | Data & Knowledge En- gineering2009，68，2： | 1 |
| 7 | The level of awareness of stroke risk factoris and sympotms in the Gulf Cooperation Council countries:Gulf Cooperation Council stroke awareness study显示文摘 | Kamran S Bener AB Deleu D | 2007 | Neuroepidemiology2007，29，34： | 1 |
| 8 | fMRI activation during spike and wave discharges in idiopathic generalized epilepsy显示文摘 | Aghakhani Y Bagshaw AP Bener CG | 2004 | Brain2004，127，5： | 1 |
| 9 | Temporal lobe epilepsy in children:Etiology in a cohort with new-onset seizures显示文摘 | Sztriha L Gururaj AK Bener A | 2002 | Epilpesia2002，43，1： | 1 |
| 10 | Is male fertility associated with type 2 diabetes mellitus显示文摘 | Bener A Al Ansari AA Zirie M | 2009 | Int Urol Nephrol2009，41，4： | 1 |
| 11 | Dexmedetomidine during local anesthesia显示文摘 | Abdalla MI AI Mansouri F Bener A | 2006 | J Anesth2006，20，1： | 1 |
| 12 | Prevalence of gestational diabetes and asso- ciated maternal and neonatal complications in a fast - developing community: global comparisons 显示文摘 | Bener A Saleh NW | 2011 | International Journal of Women'' s Health2011，11，74： | 1 |
| 13 | Prevalence of gestational diabetes and associated maternal and neonatal complications in a fast-developing community-global comparisons 显示文摘 | Bener A Saleh NM Al-Hamaq A | 2011 | Int J Womens Health2011，3，： | 1 |
| 14 | Genetic and environmental factors associated with asthma 显示文摘 | Bener A Abdulrazzaq YM Al-Mutawwa J | 1996 | Hum Biol1996，68，3： | 1 |
| 15 | Pet ownership in the UAE: its effect on allergy and respiratory symptoms显示文摘 | Abdulrazza YM Bener A de Buse P | 1995 | J Asthma1995，32，： | 1 |
| 16 | Dexmedetomidine during local anesthesia显示文摘 | Abdalla MI A1 Mansouri F Bener A | 2006 | J Anesth2006，20，1： | 1 |
| 17 | Dissolved and particulate phosphorus forms in a eutrophic shallow lake显示文摘 | Uwe Selig Thomas Hübener Manfred Michalik | 2002 | Aquatic Sciences2002，，1： | 1 |
| 18 | Consanguinity and family history nf cancer in children with leukemia and lymphomas 显示文摘 | Bener A Denic S AL-Mazrouei M | 2001 | Cancer2001，92，1： | 1 |
| 19 | Impacts of family history and lifestyle habits on colorectal cancer risk: a case-control study in Qatar显示文摘 | Bener A Moore MA Ali R et a! | 2010 | Asian Pac J Cancer Prey2010，11，4： | 1 |
| 20 | Dexmedetomidine during local anesthesia显示文摘 | Abdalla MI Al Mansouri F Bener A | 2006 | J Anesth2006，20，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员