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| 1 | Association of autoimmune hepatitis and systemic lupus erythematodes:A case series and review of the literature显示文摘Liver test abnormalities have been described in up to 60% of patients with systemic lupus erythematodes(SLE) at some point during the course of their disease.Prior treatment with potentially hepatotoxic drugs or viral hepatitis is commonly considered to be the main cause of liver disease in SLE patients.However,in rare cases elevated liver enzymes may be due to concurrent autoimmune hepatitis(AIH).To distinguish whether the patient has primary liver disease with associated autoimmune clinical and laboratory features resembling SLE- such as AIH- or the elevation of liver enzymes is a manifestation of SLE remains a difficult challenge for the treating physician.Here,we present six female patients with complex autoimmune disorders and hepatitis.Patient charts were reviewed in order to investigate the complex relationship between SLE and AIH.All patients had coexisting autoimmune disease in their medical history.At the time of diagnosis of AIH,patients presented with arthralgia,abdominal complaints,cutaneous involvement and fatigue as common symptoms.All patients fulfilled the current diagnostic criteria of both,AIH and SLE.Remission of acute hepatitis was achieved in all cases after the initiation of immunosuppressive therapy.In addition to this case study a literature review was conducted. | Claudia Beisel Christina Weiler-Normann Andreas Teufel Ansgar W Lohse | 2014 | World Journal of Gastroenterology2014，20，35： | 2 |
| 2 | Reliable detection of subclonal single-nueleotide variants in tumour cell populations 显示文摘 | GERSTUNG M BEISEL C RECHSTEINER M | 2012 | Nat Commun2012，36，3： | 1 |
| 3 | Epigenetic regulation in Drosophila 显示文摘 | Lyko F Beisel C Marhold J | 2006 | Curr Top Microbiol Immunol2006，310，： | 1 |
| 4 | A chromatin-modifying function of JNK during stem cell differentiation显示文摘 | Tiwari V K Stadler M B Wirbelauer C Paro R Schübeler D Beisel C | | 0，，： | 1 |
| 5 | Molecular evolution of the vertebrate mechanosensory cell and ear显示文摘 | Fritzsch B Beisel KW Pauley S | 2007 | Int J Dev Biol2007，51，67： | 1 |
| 6 | Seroconversion of HBsAG coincides with hepatitis A superinfection: A case report显示文摘BACKGROUND Hepatitis B virus(HBV)is a hepatotropic virus that can cause acute and chronic liver damage.According to the world health organization 257 million people are infected with chronic HBV infection worldwide.Super-infection with other hepadnaviruses,including hepatitis A virus(HAV),hepatitis C virus,hepatitis D virus,and hepatitis E virus is associated with increased risk of acute liver failure in patients with chronic HBV.CASE SUMMARY Here,we report a case of a 47-year old male patient with HBV-related compensated Child A cirrhosis,who presented with general fatigue,malaise and laboratory signs of acute hepatitis.Although the patient was regularly seen at a specialized university liver unit,the HAV vaccination status was unclear.Acute HAV super-infection was diagnosed by positive serological and polymerase chain reaction analysis.Following acute HAV super-infection,spontaneous HBsAg elimination and development of an anti-HBs titer were observed.CONCLUSION This case illustrates the importance of carefully checking the vaccination status.In our patient,unspecific immunological responses to HAV led to functional cure of HBV. | Claudia Beisel Marylyn M Addo Julian Schulze zur Wiesch | 2020 | World Journal of Clinical Cases2020，8，9： | 1 |
| 7 | infection induced malnutrition from cholera to cytokines显示文摘 | Beisel WR Herman award lecture | 1995 | Am J Clin Nutr1995，62，： | 1 |
| 8 | Myocarditis-indu- cing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting ceils in the heart 显示文摘 | Donermeyer DL Beisel KW Alien PM | 1995 | J Exp Med1995，182，5： | 1 |
| 9 | The spatial heterogeneity of a river bottom: a key factor determining macroinvertebrate communities显示文摘 | Jean-Nicolas Beisel Philippe Usseglio-Polatera Jean-Claude Moreteau | 2000 | Hydrobiologia2000，，0： | 1 |
| 10 | Biodiversity and Structure of Macroinvertebrate Communities Along a Small Permanent Salinity Gradient (Meurthe River,France)显示文摘 | PISCART C MORETEAU J C BEISEL J N | 2005 | Hydrobiologia2005，551，1： | 1 |
| 11 | Stream community structure in relation to spatial variation:the influence of mesohabitat characteristics显示文摘 | Beisel J N Usseglio-Polatera P Thomas S | 1998 | Hydrobiologia1998，389，： | 1 |
| 12 | The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration显示文摘 | Fritzsch B Beisel KW Hansen LA | | BioEssays0，28，： | 1 |
| 13 | Variations in the susceptibility to coxsackievirus B3 induced myocarditis among different strains of mice显示文摘 | Wolfgram LJ Beisel KW Herskowitz A | 1986 | J Immunol1986，136，5： | 1 |
| 14 | Cardiac myosin induces myoearditis in genetically predisposed mice 显示文摘 | Neu N Rose NR Beisel KW | 1987 | J Immunol1987，139，11： | 1 |
| 15 | Does posteoital voiding prevent urinary tract infections in younger women 显示文摘 | Beisel B Hale W Graves RS | 2002 | J Faro Praet2002，51，11： | 1 |
| 16 | Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1 显示文摘 | Beisel C Imhof A Greene J | 2002 | Nature2002，419，： | 1 |
| 17 | Monitoring Changes in Freshwater Macroinvertebrate Communities Along a Salinity Gradient Using Artificial Substrates显示文摘 | Christophe Piscart Jean-Claude Moreteau Jean-Nicolas Beisel | 2006 | Environmental Monitoring and Assessment (-)2006，，1： | 1 |
| 18 | Chick hair cells do not exhibit voltage-dependent somatic motility显示文摘 | He D Z Beisel K W Chen L | 2003 | J Physiol2003，546，51： | 1 |
| 19 | Stream community structure in relation to spatial variation: the influence of microhabitat characteristics 显示文摘 | BEISEL J N POLATERA P THOMAS S | 1998 | Hydrobiology1998，71，389： | 1 |
| 20 | Stem cells andmolecular strategies to restore hearing显示文摘 | Pauley S Kopecky B Beisel K | 2008 | PanminervaMed2008，50，1： | 1 |
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