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| 1 | Tau-induced neurodegeneration: mechanisms and targets显示文摘The accumulation of hyperphosphorylated tau is a common feature of several dementias. Tau is one of the brain microtubule-associated proteins. Here we discuss tau's functions in microtubule assembly and stabilization and with regard to its interactions with other proteins. We describe and analyze important post-translational modifications: hyperphosphorylation, ubiquitination, glycation, glycosylation, nitration, polyamination, proteolysis, acetylation, and methylation. We discuss how these post-translational modifi cations can alter tau's biological function. We analyze the role of mitochondrial health in neurodegeneration. We propose that microtubules could be a therapeutic target and review different approaches. Finally, we consider whether tau accumulation or its conformational change is related to tau-induced neurodegeneration, and propose a mechanism of neurodegeneration. | Cindy Beharry Leah S. Cohen Jing Di Kawsar Ibrahim Susan Briffa-Mirabella Alejandra del C. Alonso | 2014 | Neuroscience Bulletin2014，30，2： | 6 |
| 2 | Functional outcomes after open reduction and internal fixation for treatment of displaced distal radius fractures in patients over 60 years of age显示文摘 | Beharrie AW Beredjiklian FK Bozentka DJ | 2004 | J Orthop Trauma2004，18，10： | 1 |
| 3 | Expression of Alzheimer-like pathological human tau induces a behavioral motor and olfactory learning deficit in drosophila melanogaster显示文摘 | BEHARRY C ALANIZ ME ALONSO ADC | 2015 | J Alzheimers Dis2015，37，3： | 1 |
| 4 | Caffeine im- pact on neonatal morbidities显示文摘 | Aranda JV Beharry K Valencia GB | 2010 | J Matern Fetal Neonatal Med2010，23，： | 1 |
| 5 | Func- tional outcomes after open reduction and internal fixtion for treatment of displaced distal radius fractures in patients over 60 years of age 显示文摘 | BEHARRIE A W BEREDJIKLIAN P K BOZENTKA D J | 2004 | J Orthop Trauma2004，18，10： | 1 |
| 6 | The long-term functional outcome of operatively treated tibial plateau fractures显示文摘 | Stevens DG Beharry R Mckee MD | 2001 | J Orthop Trauma2001，15，5： | 1 |
| 7 | The long-term functional outcome of operatively treated tibial plateau fraetures显示文摘 | Stevens DG Beharry R McKee MD | 2001 | J Orthop Trauma2001，15，： | 1 |
| 8 | Combined effects of antenatal corticosteroids and surfactant supplementation on the outcome of very low birth weight infants显示文摘 | Modanlou HD Beharry K Padilla G | 1996 | J Perinatol1996，16，6： | 1 |
| 9 | Caffeine impact on neonatal morhidities显示文摘 | Aranda JV Beharry K Valencia GB | 2010 | J Matem Fetal Neonatal Med2010，23，： | 1 |
| 10 | The long - term functional outcome of operatively treated fibial plateau fractures显示文摘 | Stevens DG Beharry R Mckee MD | 2001 | J Orthop Trauma2001，15，： | 1 |
| 11 | Effects of brief, clustered versus dispersed hypoxic episodes on systemic and ocular growth factors in a rat model of oxygen- induced retinopathy 显示文摘 | Coleman R J Beharry KD Brock RS | 2008 | Pediatr Res2008，64，1： | 1 |
| 12 | High pressure liquid chromatographic microassay for simultaneous measurement of doxapram and its metabolites in prematurre newborn infanta显示文摘 | Aranda JV Beharry K Rex K | 1988 | Journal of Chromatography1988，11，： | 1 |
| 13 | Serum pancreatic enzymes define the pancreatic phenotype in patients with Shwachman-Diamond syndrome显示文摘 | Ip WF Dupuis A Ellis L Beharry S MorrisonJ Stormon MO | 2002 | J Pediatr2002，141，2： | 1 |
| 14 | Func- tional outcomes after open reduction and internal fixtion for treatment of displaced distal radius fractures in patients over 60 years of age显示文摘 | BEHARRIE A W BEREDJIKLIAN P K BOZENTKA D 2 | 2004 | J Orthop Trauma2004，18，10： | 1 |
| 15 | The long-term functional outcome of operatively treated tibial plateau fractures显示文摘 | Stevens DG Beharry R Mckee MD | 2001 | J Orthop Trauma2001，15，5： | 1 |
| 16 | Binding of N-retinylidene-PE to ABCA4 and a model for its transport across membranes显示文摘 | Molday RS Beharry S Ahn J | 2006 | Adv Exp Med Biol2006，572，： | 1 |
| 17 | 显示文摘 | Beharry S Ellis L Corey M | 2002 | J Pediatr2002，141，1： | 1 |
| 18 | Epitope mapping and use of epitope-specific antisera to characterize the VP5*binging site in rotavirus SA11 NSP4显示文摘 | HYSER J M ZENG C Q BEHARRY Z | 2008 | Virology2008，373，1： | 1 |
| 19 | Functional out-comes after open reduction and internal fixation for treatment of displaced distal radius fractures in patients over 60 years of age显示文摘 | Beharrie AW Bereajiklian PK Bozentka DJ | 2004 | J Orthop Trauma2004，18，10： | 1 |
| 20 | Comparative efficacy of exosurf and survanta surfactants on early clinical course of respiratory distress syndrome and complications of prematurity 显示文摘 | Modanlou HD Beharry K Padilla G | 1997 | J Perinatol1997，17，6： | 1 |
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