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| 1 | Thymosin alpha 1:A comprehensive review of the literature显示文摘Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies,as an enhancer of vaccine response,and as a means of curbing morbidity and mortality in sepsis and numerous infections.Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill corona virus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.In this review,we discuss key literature on the background knowledge and current clinical uses of thymosin alpha 1.Considering the known biochemical properties including antibacterial and antiviral properties,timehonored applications,and the new promising findings regarding the use of thymosin,we believe that thymosin alpha 1 deserves further investigation into its antiviral properties and possible repurposing as a treatment against severe acute respiratory syndrome coronavirus-2. | Asimina Dominari Donald Hathaway III Krunal Pandav Wanessa Matos Sharmi Biswas Gowry Reddy Sindhu Thevuthasan Muhammad Adnan Khan Anoopa Mathew Sarabjot Singh Makkar Madiha Zaidi Michael Maher Mourad Fahem Renato Beas Valeria Castaneda Trissa Paul John Halpern Diana Baralt | 2020 | World Journal of Virology2020，9，5： | 11 |
| 2 | A simple Tenax? extraction method to determine the availability of sediment‐sorbed organic compounds显示文摘 | GerardCornelissen HenkRigterink Dorien E. M.ten Hulscher Bea A.Vrind Paul C. M.van Noort | 2009 | Environmental Toxicology and Chemistry2009，，4： | 2 |
| 3 | Effect oftedon transfers and extra-articular soft-tissue balancing on glenohumeral development in brachial plexus birth palsy显示文摘 | Bea DS | 2005 | J Bone Joint Surg2005，87，： | 1 |
| 4 | Differential expression of cdc25 cell- cycle - activating phosphatases in human colorectal carcinoma显示文摘 | Hernandez S Bessa X Bea S | 2001 | Lab Invest2001，81，4： | 1 |
| 5 | Life-cycle reliability characteristics of minimum structures显示文摘 | R G Bea A Brandtzaeg M J K Craig | 1998 | Journal of Offshore mechanics and Arctic Engineering1998，120，： | 1 |
| 6 | Life-cycle reliability characteristics of minimum structures显示文摘 | Bea R G Brandtzaeg A Craig M J K | 1998 | Journal of Offshore Mechanics and Arctic Engineering1998，120，： | 1 |
| 7 | The synthesis of a zeolite via pseudomorphic crystallization 显示文摘 | CHOI M NA K RYO0 hierarchically porous BEA R | 2009 | Chemical Communications2009，，20： | 1 |
| 8 | Kinetics of adsorption and desorption of some organochlorine compounds on black carbon in a sediment显示文摘 | Bea A.Vrind Theodora E. M.ten Hulscher Paul C. M.van Noort | 2009 | Environmental Toxicology and Chemistry2009，，4： | 1 |
| 9 | Hematoma enlargement 显示文摘 | Bea H G Lee K S Yun I C | 1995 | Neurosurgery1995，12，23： | 1 |
| 10 | Impact of post-stroke cogni tive impairment with no dementia on health-related quality of life显示文摘 | PARK J H KIM B J BEA H J | 2013 | J Stroke2013，15，1： | 1 |
| 11 | A G{alpha}i-GIV molec-ular complex binds epidermal growth factor receptor and determineswhether cells migrate or proliferate显示文摘 | Ghosh P Beas AO Bornheimer SJ | 2010 | Mol Biol Cell2010，21，13： | 1 |
| 12 | Comparative Risk Assessment of Alternative TLP Systems: Structure and Foundation Aspect显示文摘 | R G Bea | 1994 | Journal of OMAE1994，116，： | 1 |
| 13 | Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma显示文摘 | HERNANDEZ S BESSA X BEA S | 2001 | Lab Invest2001，81，4： | 1 |
| 14 | BMI-1 gene amplication and overexpression in hematological malignancies occur mainly in mantle cell lymphomas显示文摘 | BEA S TORT F PUIG X | 2001 | Cancer Res2001，84，9： | 1 |
| 15 | CDC25A and the splicing variant CDC25B2, but not CDC25B1, -B3 or-C, are over-expressed in aggressive human non-Hodgkin's lymphomas 显示文摘 | HERNANDEZ S HERNANDEZ L BEA S | 2000 | Int J Cancer2000，89，2： | 1 |
| 16 | Telomerase and Telomeres: From Basic Biology to Cancer Treatment显示文摘 | Marco N. Helder G. Bea A. Wisman Ate G. J. van der Zee | 2002 | Cancer Investigation2002，，1： | 1 |
| 17 | Edge Disjoint Hamiltonian Cycles in k-Ary n-Cubes and Hypercubes显示文摘 | Bea M M Bose B | 2003 | IEEE Transactions on Computers2003，52，10： | 1 |
| 18 | Successful treatment of erosive vulvar lichen sclerosus with methylaminolaevulinic acid and laser-mediated photodynamic therapy显示文摘 | Vano GS Fernandez GM Bea AS | 2009 | J Eur Acad Dermatol Venereol2009，23，1： | 1 |
| 19 | Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression - based proliferation signature显示文摘 | Salaverria I Zettt A Bea S | 2007 | J Clin Oncol2007，25，10： | 1 |
| 20 | Triode Field Emitterswith Planar Carbon-Nanoparticle Cathodes显示文摘 | Kyung Ho Park Sungil Bea Soonil Lee | 2006 | Current Ap-plied Physics2006，6，6： | 1 |
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