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| 1 | Oxidative damage in the progression of chronic liver disease to hepatocellular carcinoma:An intricate pathway显示文摘The histo-pathologic and molecular mechanisms leading to initiation and progression of hepatocellular carcinoma(HCC)are still ill-defined;however,there is increasing evidence that the gradual accumulation of mutations,genetic and epigenetic changes which occur in preneoplastic hepatocytes results in the development of dysplastic foci,nodules,and finally,overt HCC.As well as many other neoplasias,liver cancer is considered an'inflammatory cancer',arising from a context of inflammation,and characterized by inflammation-related mechanisms that favor tumor cell survival,proliferation,and invasion.Molecular mechanisms that link inflammation and neoplasia have been widely investigated,and it has been well established that inflammatory cells recruited at these sites with ongoing inflammatory activity release chemokines that enhance the production of reactive oxygen species.The latter,in turn,probably have a major pathogenic role in the continuum starting from hepatitis followed by chronic inflammation,and ultimately leading to cancer.The relationship amongst chronic liver injury,free radical production,and development of HCC is explored in the present review,particularly in the light of the complex network that involves oxidative DNA damage,cytokine synthesis,telomere dysfunction,and microRNA regulation. | Romilda Cardin Marika Piciocchi Marina Bortolami Andromachi Kotsafti Luisa Barzon Enrico Lavezzo Alessandro Sinigaglia Kryssia Isabel Rodriguez-Castro Massimo Rugge Fabio Farinati | 2014 | World Journal of Gastroenterology2014，20，12： | 14 |
| 2 | Primary bílateral adrenal B-cell lymphoma associated with EBV and JCV infection显示文摘 | Barzon L Trevisan M Marino F | 2009 | Infect Agent Cancer2009，4，4： | 1 |
| 3 | Diagnosis and management of adrenal incidentalomas 显示文摘 | Barzon L Boscaro M | 2000 | J Urol2000，163，2： | 1 |
| 4 | Therapy with glycosaminoglycans lowers albumin excretion in non- insulin dependent diabetic patients with microalbumin- uria显示文摘 | Solini A Carraro A Barzon I | 1994 | Diabetes Nutr Metab1994，7，： | 1 |
| 5 | Development of overt Cush- ing's syndrome in patients with adrenal incidentalomas显示文摘 | Barzon L Fallo F Sonino N | 2002 | Ettro J Endocrinol2002，146，1： | 1 |
| 6 | An upgraded brazing technique to manufacture ceramic-metal joints for UHV applications显示文摘 | Murari A Albrecht H Barzon A | 2002 | Vacuum2002，68，4： | 1 |
| 7 | Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and Herpes Simplex Vires thymidine kinase显示文摘 | Barzon L Bonaguro R Castagliuolo I | 2003 | Eur J Endoefinol2003，148，1： | 1 |
| 8 | Prevalence and natural history of adrenal incidentalomas显示文摘 | Barzon L Sonino N Fallo F | 2003 | Eur J Endocfinol2003，149，4： | 1 |
| 9 | Prevalence and natural history of adrenal incidentalomas显示文摘 | Barzon L Sonino N Fallo F | 2003 | Eur J Endocrinol2003，149，： | 1 |
| 10 | Purification ofmitochondrial thioredoxin reductase and its involvement in the redox regu-lation of membrane permeability显示文摘 | RIGOBELLO M P CALLEGARO M T BARZON E | 1998 | Free Radical Biology&Medicine1998，24，2： | 1 |
| 11 | Diagnosis and management of adrenal incidentalomas显示文摘 | Barzon L Boscaro M | 2000 | J Urol2000，163，： | 1 |
| 12 | Development of overt Cushing's syndrome in patients with adrenal incidentaloma显示文摘 | Barzon L Fallo F Sonino N | | 0，，01： | 1 |
| 13 | Development of overt Cushing's syndrome in patients with adrenal incidentalomas显示文摘 | Fallo F Sonino N | 2002 | Eur J Endocrinol2002，146，1： | 1 |
| 14 | Distribution of human papillomavirus types in the anogenital tract of females and males显示文摘 | Barzon L Militello V Pagni S | 2010 | J Med Virol2010，82，： | 1 |
| 15 | Incidentally discovered adrenal tumors:endocrine and scintigraphic correlates显示文摘 | Barzon L Scaroni C Sonino N | | 0，，01： | 1 |
| 16 | Comparison of methods to identify individuals at increased risk of cardiovascular disease in Italian cohorts显示文摘 | Giavarina D Barzon E Cigolini M | 2007 | Nutr Metab Cardiovasc Dis2007，17，4： | 1 |
| 17 | Development of overt cushing's syndromein patients with adrenal incidentaloma显示文摘 | Fallo F Soninon N | 2002 | Eur J Endo2002，146，： | 1 |
| 18 | Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme:biological and clinical results显示文摘 | Colombo F Barzon L Franchin E | 2005 | Cancer Gene Ther2005，12，： | 1 |
| 19 | New perspectives for gene therapy in endocrinology显示文摘 | Barzon L Bonaguro R Palu G | 2000 | European journal of endocrinology2000，143，4： | 1 |
| 20 | Diagnosis and management of adrenal incidentalomas显示文摘 | Boscaro M | 2000 | J Urol2000，163，2： | 1 |
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