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69篇 您的检索式：作者名="Baroukh"

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	题名	作者	年代	出处	被引量
1	Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/-IVS8Tn:T7/9 patient with acute recurrent pancreatitis显示文摘BACKGROUND Acute recurrent pancreatitis(ARP)is characterized by episodes of acute pancreatitis in an otherwise normal gland.When no cause of ARP is identifiable,the diagnosis of'idiopathic'ARP is given.Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR)gene increase the risk of ARP by 3-to 4-times compared to the general population,while cystic fibrosis(CF)patients present with a 40-to 80-times higher risk of developing pancreatitis.CASE SUMMARY In non-classical CF or CFTR-related disorders,CFTR functional tests can help to ensure a proper diagnosis.We applied an individualized combination of standardized and new CFTR functional bioassays for a patient referred to the Verona CF Center for evaluation after several episodes of acute pancreatitis.The CFTR genotype was G542X+/-with IVS8Tn:T7/9 polymorphism.The sweat(Cl-)values were borderline.Intestinal current measurements were performed according to the European Cystic Fibrosis Society Standardized Operating Procedure.Recent nasal surgery for deviated septum did not allow for nasal potential difference measurements.Lung function and sputum cultures were normal;azoospermia was excluded.Pancreas divisum was excluded by imaging but hypoplasia of the left hepatic lobe was detected.Innovative tests applied in this case include sweat rate measurement by image analysis,CFTR function in monocytes evaluated using a membrane potential-sensitive fluorescent probe,and the intestinal organoids forskolin-induced swelling assay.CONCLUSION Combination of innovative CFTR functional assays might support a controversial diagnosis when CFTR-related disorders and/or non-classical CF are suspected.	Sara Caldrer Gabriella Bergamini Angela Sandri Silvia Vercellone Luca Rodella Angelo Cerofolini Francesco Tomba Filippo Catalano Luca Frulloni Mario Buffelli Gloria Tridello Hugo de Jonge Baroukh Maurice Assael Claudio Sorio Paola Melotti	2019	World Journal of Clinical Cases2019，7，22：	2
2	Function of microRNA-375 and microRNA-124a in pancreas and brain显示文摘	BAROUKH N N VAN OBBERGHEN E		0，，22：	1
3	miR-375 targets 3 ' - phosphoinositide - dependent protein kinase- 1 and regulates glucose induced biological responses in pancreatic β-cells显示文摘	El Ouaamari A Baroukh N Martens GA	2008	Diabetes2008，57，10：	1
4	MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines 显示文摘	Baroukh N Ravier MA Loder MK	2007	J Biol Chem2007，282，19：	1
5	MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic β-Cell Lines显示文摘	Baroukh N Ravier MA Loder MK	2007	J Biol Chem2007，282，19：	1
6	Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceriderich lipoproteins and removal of their remnants显示文摘	Grosskopf I Baroukh N Lee SJ		0，，12：	1
7	Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants显示文摘	Grosskopf I Baroukh N Lee SJ Kamari Y Harats D Rubin EM	2005	Arterioscler Thromb Vasc Biol2005，25，12：	1
8	A new approachto treat tissue destruction in periodontitis with chemically modi-fied dextran polymers显示文摘	Eseartin Q Lallam-Laroye C Baroukh B	2003	FASEB J2003，17，6：	1
9	miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells 显示文摘	El Ouaamari A Baroukh N Martens GA	2008	Diabetes2008，57，10：	1
10	Chemical sympathectomy impairs bone resorption in rats:a role for the sympathetic system on bone metabolism显示文摘	Cherruau M Facchinetti P Baroukh B	1999	Bone1999，25，5：	1
11	MicroRNA-124a regu- lates Foxa2 expression and intracellular signaling in pancreatic be- ta-cell lines显示文摘	Baroukh N Ravier MA Loder MK	2007	J Biol Chem2007，282，19：	1
12	MicroRNA-124a regulates Foxa2 expressionand intracellular signaling in pancreatic beta-cell lines显示文摘	Baroukh N Ravier MA Loder MK	2007	J Biol Chem2007，282，19：	1
13	miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-indueed biological responses in pancreatic β-cells显示文摘	El Ouaamari A Baroukh N Martens GA		0，，：	1
14	Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants显示文摘	Grosskopf I Baroukh N Lee SJ	2005	Arterioscler Thromb Vasc Biol2005，25，12：	1
15	MiR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells显示文摘	Elouaamari A Baroukh N Martens G A	2008	Diabetes2008，57，10：	1
16	Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants 显示文摘	Grosskopf I Baroukh N Lee SJ	2005	Arterioscler Thromb Vasc Biol2005，25，：	1
17	MicroR- NA-124a regulates Foxa2 expression and intraeellular signaling in pancreatic β-Cell Lines 显示文摘	BAROUKH N RAVIER MA LODER MK	2007	J Biol Chem2007，282，19：	1
18	miR-375 targets 3r-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological reslJonses in pancreatic beta-cells显示文摘	E10uaarnari A Baroukh N Martens GA	2008	Diabetes2008，57，10：	1
19	miR-375 targets 3'-phosph- -oinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells 显示文摘	El Ouaamari A Baroukh N Martens GA	2008	Diabetes2008，57，10：	1
20	miR-375 targets 3- phosphoinositide-depertdent protein kinase-l and regulates glu- cose induced diological responses in pancreatic beta-cells 显示文摘	El Ouaamari A Baroukh N Martens G	2008	Diabetes2008，57，10：	1

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