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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Rapid and robust slope failure appraisal using aerial photogrammetry and 3D slope stability models显示文摘Slope failures are an inevitable aspect of economic pit slope designs in the mining industry.Large open pit guidelines and industry standards accept up to 30%of benches in open pits to collapse provided that they are controlled and that no personnel are at risk.Rigorous ground control measures including real time monitoring systems at TARP(trigger-action-response-plan)protocols are widely utilized to prevent personnel from being exposed to slope failure risks.Technology and computing capability are rapidly evolving.Aerial photogrammetry techniques using UAV(unmanned aerial vehicle)enable geotechnical engineers and engineering geologists to work faster and more safely by removing themselves from potential line-of-fire near unstable slopes.Slope stability modelling software using limit equilibrium(LE)and finite element(FE)methods in three dimensions(3D)is also becoming more accessible,user-friendly and faster to operate.These key components enable geotechnical engineers to undertake site investigations,develop geotechnical models and assess slope stability faster and in more detail with less exposure to fall of ground hazards in the field.This paper describes the rapid and robust process utilized at BHP Limited for appraising a slope failure at an iron ore mine site in the Pilbara region of Western Australia using a combination of UAV photogrammetry and 3D slope stability models in less than a shift(i.e.less than 12 h). | Neil Bar Michael Kostadinovski Michael Tucker Glen Byng Rully Rachmatullah Arturo Maldonado Markus Pötsch Andreas Gaich Alison McQuillan Thamer Yacoub | 2020 | International Journal of Mining Science and Technology2020，30，5： | 2 |
| 3 | Spinal cord injury:bridging the lesion and the role of neurotrophic factors in repair 显示文摘 | Houweling D A Bar P R Gispen W H | 1998 | Prog Brain Res1998，117，： | 1 |
| 4 | A multidisciplinary field hospital as a substitute for medical hospital care in the aftermath of an earthquake: the experience of the Israeli Defense Forces Field Hospital in Duzce ,Turkey, 1999 显示文摘 | Bar Dayan Y Leiba A Beard P | 2005 | Prehosp Disaster Med2005，20，2： | 1 |
| 5 | Contrasting values of cultural ecosystem services in urban areas:the case of park Montjuc in Barcelona显示文摘 | LANGEMEYER J BARF ROEBELING P | 2015 | Ecosystem Services2015，12，： | 1 |
| 6 | Tiotropium bromide : a novel oncedaily anticholinergic bronchodilator for the treatment of COPD 显示文摘 | HANSEL T T BARNESS P J | 2002 | Drugs Today( Barc )2002，38，9： | 1 |
| 7 | A placebo- controlled,dauble- blind, randomized trial of an extract of Ginkgo biloha for dementia显示文摘 | Bars P L Katz M M Berman N | 1997 | J Am Med Assoc1997，278，： | 1 |
| 8 | DNA com- mission of the international society for forensic ge- netics: guidelines for mitochondrial DNA typing显示文摘 | Carracedo A Bar W Lincoln P eta! | 2000 | Forensic Sci Int2000，110，2： | 1 |
| 9 | Thermo stability of ochratoxin A in wheat under two moisture conditions显示文摘 | Boudra H Le Bars P Le Bars J | 1995 | Ap plied and Environmental Microbiology1995，，61： | 1 |
| 10 | The Interacting Multiple Model Algorithm for Systems with Markovian Switching Coefficients显示文摘 | Blom H A P Bar S Y | 1988 | IEEE Transactions on Automatic Control1988，33，8： | 1 |
| 11 | Urban land-use allocation in a Mediterranean ecotone: Habitat Heterogeneity Model incorporated in a GIS using a multi-criteria mechanism显示文摘 | Svoray T Bar P Banner T | 2005 | Landscape and Urban Planning2005，72，4： | 1 |
| 12 | Characterization of monaacidin A from Monaacus as citrinin显示文摘 | Blanc P J Laussac J P Le Bars J | 1995 | Int J Food Microbiol1995，27，23： | 1 |
| 13 | New flame retardant systems for styrenic plastics and method of preparation 显示文摘 | Finberg I Bar Yaakov Y Georlette P | 1999 | Polymer Degradation and Stability1999，64，3： | 1 |
| 14 | Glial-derived neurotrophic factor in human adult and fetal intestine and in Hirschsprung's disease 显示文摘 | Bar K J Facer P Williams NS | 1997 | Gastroenterology1997，112，4： | 1 |
| 15 | Thermostability of fumonisin B1 , a mycotoxin from Fusarium moniliforme, in corn 显示文摘 | Dupuy J Bars P L Boudra H | 1993 | Applied and Environmental Microbiology1993，59，9： | 1 |
| 16 | Coexistence of fast photodarkening and slow photobleaching in GelgAs21Se60 thin films 显示文摘 | KHAN P BAR/K A R VINOD E M | 2012 | Opt Express2012，20，12： | 1 |
| 17 | The Interacting Multiple Model Algorithm for Systems with Markovian Switching Coeficients显示文摘 | Blom H A P Bar Shalom Y | 1988 | IEEE Trans on Autom Control1988，33，8： | 1 |
| 18 | Type IV collagen and CD44v6 expression in benign, malignant primary and metastatic ovarian tumors: correlation with Ki-67 and p53 immunoreactivity显示文摘 | Bar JK Grelewski P Popiela A | 2004 | Gynecol Oncol2004，95，1： | 1 |
| 19 | Characterization of monascidin A from Monascus as citrinin显示文摘 | P J Blanc J P Laussac J L Bars P L Bars M O Lotet A Pareilleux D Prome J C Prome A L Santerre G Goma | 1995 | International Journal of Food Microbiology1995，27，： | 1 |
| 20 | Characterization of monascidin A from Monascus as citrinin显示文摘 | BLANC P J LAUSSAC J P BARS J L | 1995 | International Journal of Food Microbiology1995，27，： | 1 |
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