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| 1 | Pancreaticoduodenectomy: a comparison of superior approach with classical Whipple's technique显示文摘BACKGROUND: Pancreaticoduodenectomy (PD) is the standard procedure for resecting tumors arising from the periampullary area and the pancreatic head. Nevertheless this procedure is inherently difficult and associated with high morbidity and mortality. Besides, the technique applied for exposing the portal and superior mesenteric veins is time-consuming, difficult and associated with the risk of major venous injury. Recently we have introduced a modified approach for making this part of the procedure quick, safe and bloodless, which constitutes the subject of this study. METHODS: Patients who underwent pylorus preserving pancreaticoduodenectomy (PPPD) either by superior approach technique (group 1) or by classical Whipple's technique (group 2) were retrospectively identified. Age-sex composition, body mass index (BMI), total operative time, operative blood loss, intraoperative blood transfusion requirement, morbidity, mortality and length of hospital stay were compared between the two groups. RESULTS: Between January 1997 and December 2011, 72 patients underwent PPPD by the superior approach technique (group 1) and 38 underwent PPPD by the classical Whipple's technique (group 2) at our institution. Statistically significant differences were observed in operative time (208.1±46.3 minutes in group 1 vs 322.0±33.8 minutes in group 2), operative blood loss (601.0±250.3 mL in group 1 vs 1371.5±471.8 mL in group 2), and intraoperative blood transfusion requirement [10 (13.9%) patients in group 1 and 24 (63.2%) in group 2]. Among 18 (16.4%) obese patients, significant differences in operativetime, operative blood loss and intraoperative blood transfusion requirement were observed between groups 1 and 2. There was no significant inter-group difference in complication rate among obese patients, but comparing obese patients with normal weight patients revealed higher rates of complications like pancreatic fistula (27.8% vs 6.5%), delayed gastric emptying (16.7% vs 5.4%), and infective complications like wound infection and intra abdominal collection (44.4% vs 5.4%). CONCLUSIONS: On the basis of analytical data, we conclude that the superior approach technique is effective for PD compared with the classical Whipple's technique. It allows fast, safe and virtually bloodless dissection for exposure of the superior mesenteric and portal veins during early steps of PD. PD is normally a difficult and tedious procedure carrying a remote risk of major venous injury leading to substantial blood loss. | Omar Javed Shah Mushtaq A Gagloo Irfan Jan Khan Rayees Ahmad Saleema Bano | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，2： | 8 |
| 2 | Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains显示文摘Objective:To investigate the in vitro antimicrobial activities of the leaf extract in different solvents viz.,methanol,ethanol and water extracts of the selected plant Ricinus communis.Methods:Ager well diffusion method and agar tube dilution method were carried out to perform the antibacterial and antifungal activity of methanol,ethanol and aqueous extracts.Results:Metbanol leaf extracts were found to be more active against Gram positive bacteria(Bacillus subtilis:ATCC 6059 and Staphylococcus aureus:ATCC 6538)as well as Gram negative bacteria(Pseudomonas aeruginosa:ATCC 7221 and Klebsiella pneumoniae)than ethanol and aqueous leaf extracts.Antifungal activity of methanol and aqueous leaf extracts were also carded out against selected fungal strains as Aspergillus fumigatus and Aspergillus flavus.Methanolic as well as aqueous leaf extracts of Ricinus communis were effective in inhibiting the fungal growth.Conclusions:The efficient antibacterial and antifungai activity of Ricinus communis from the present investigation revealed that the methanol leaf extracts of the selected plant have significant potential to inhibit the growth of pathogenic bacterial and fungal strains than ethanol and aqueous leaf extracts. | Rabia Naz Asghari Bano | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，12： | 4 |
| 3 | Predictions of future hydrological conditions and contribution of snow and ice melt in total discharge of Shigar River Basin in Central Karakoram,Pakistan显示文摘The high mountains of Hindu-Kush Karakoram and Himalaya(HKKH) contain a large volume of snow and ice, which are the primary sources of water for the entire mountainous population of HKKH. Thus, knowledge of these available resources is very important in relation to their sustainable use. A Modified Positive Degree Day Model was used to simulate daily discharge with the contribution of snow and ice melt from the Shigar River Basin, Central Karakoram, Pakistan. The basin covers an area of 6,921 km2 with an elevation range of 2,204 to 8,611 m a.s.l.. Forty percent of the total area is glaciated among which 20% is covered by debris and remaining 80% by clean ice and permanent snow. To simulate daily discharge, the entire basin was divided into 26 altitude belts. Remotely sensed land cover types are derived by classifying Landsat images of 2009. Daily temperature and precipitation from Skardu meteorological station is used to calibrate the glacio-hydrological model as an input variable after correlating data with the Shigar station data(r=0.88). Local temperature lapse rate of 0.0075 °C/m is used. 2 °C critical temperature is used to separate rain and snow from precipitation. The model is calibrated for 1988~1991 and validated for 1992~1997. The model shows a good Nash-Sutcliffe efficiency and volume difference in calibration(0.86% and 0.90%) and validation(0.78% and 6.85%). Contribution of snow and ice melt in discharge is 32.37% in calibration period and 33.01% is validation period. The model is also used to predict future hydrological regime up to 2099 by using CORDEX South Asia RCM considering RCP4.5 and RCP8.5 climate scenarios.Predicted future snow and ice melt contributions in both RCP4.5 and RCP8.5 are 36% and 37%, respectively. Temperature seems to be more sensitive as compared to other input variables, which is why the contribution of snow and ice in discharge varies significantly throughout the whole century. | Javed Hassan Rijan Bhakta Kayastha Ahuti Shrestha Iram Bano Sayed Hammad Ali Haleem Zaman Magsi | 2017 | Research in Cold and Arid Regions2017，9，6： | 3 |
| 4 | Metamorphosis of the malaria parasite in the liver is associated with organelle clearance显示文摘当他们在他们的脊椎动物宿主和蚊子向量之间骑车,疟疾寄生虫遇到多样的条件。在这些不同环境以内,寄生虫经历激烈的转变,改变它的形态学和新陈代谢。变形体种类感染哺乳动物必须首先在开始红血房间感染前在肝收起住处。后面的穿入进 hepatocytes,寄生虫从侵略能干的、能动、伸长的孢子虫变换成新陈代谢地活跃的、圆 trophozoite。相对,很少对涉及孢子虫变形的细胞的事件被知道。我们的数据揭开与这些转变联系的早细胞的事件。我们说明变形的开始是,这在血浆膜下面由膜细胞骨架的混乱标记,它在原子核附近导致一个耸出的区域。当这个球状的区域膨胀,孢子虫的二远侧的结束逐渐地缩回并且消失,导致房间 sphericalization。这个形状变化与过剩细胞器的主要内部革新和清理被联系,例如涉及侵略的 micronemes。膜细胞骨架在细胞质以内被重新组织进稠密的薄片状的数组并且部分是由变换寄生虫的 expulsed。同时, micronemes 被划分进大 exocytic 泡并且然后被解除进环境。在变形的结束,寄生虫仅仅保留为复制必要的细胞器。这些观察放了地基因为发展小径上的进一步的调查在疟疾寄生虫的变形含有。 | Bamini Jayabalasingham Nazneen Bano Isabelle Coppens | 2010 | Cell Research2010，20，9： | 2 |
| 5 | Modeling of GPR waves for lossy media obeying a complex power law of frequency for dielectric permittivity 显示文摘 | Bano M | 2004 | Geophysical Prospecting2004，52，1： | 1 |
| 6 | Biodegradation of gossypol by the white oyster mushroom,Pleurotus florida,during culturing on rice straw growth substrate,supplemented with cottonseed powder显示文摘 | RAJARATHNAM S SHASHIREKHA M N BANO Z | 2001 | World Journal of Microbiology & Biotechnology2001，17，3： | 1 |
| 7 | Neuropathic pain is enhanced in delta-opioid receptor knockout mice显示文摘 | NADAL X BANOS JE KIEFFER BL | 2006 | Eur J Neurosci2006，23，3： | 1 |
| 8 | Isolation and Characterization of Phorate Degrading Soil Bacteria of Environmental and Agronomic Significance显示文摘 | BANO N MUSARRAT J | 2003 | Letters in Applied Microbiology2003，36，： | 1 |
| 9 | Influence of high carbohydrate enriched diets on plasma insulin levels and insulin and IGF-I receptors in trout 显示文摘 | Banos N Baro J Castejon C | 1998 | Reg Pept1998，77，： | 1 |
| 10 | Chitosan as a potential natural compound to control pre and post - harvest diseases of horticultural commodities显示文摘 | Bautista - Banos S Hemandez - Lauzardo A N Velazquez - del Valle M G | 2006 | Crop Pro- tection2006，25，2： | 1 |
| 11 | Photodegradation of norfloxacin in aqueous and organic solvents: a kinetic study显示文摘 | AHMAD I BANO R MUSHARRAF S G | 2015 | J Photoch Photobio A2015，302，： | 1 |
| 12 | Curriculum vitae method in science policy and research evaluation: The state- of-the-art显示文摘 | Ca~bano C Bozeman B | 2009 | Research Evaluation2009，18，2： | 1 |
| 13 | The role of CT colonography in colorectal cancer screening显示文摘 | Nicholson FB Bano JL Bartram CI | 2005 | Am J Gastroenterol2005，100，4： | 1 |
| 14 | Incidence and outcomeof small for gestational age foetuses:an experiencefrom a secondary care hospital显示文摘 | Bano R Mushtaq A Adhi M | 2013 | J Pak Med Assoc2013，63，11： | 1 |
| 15 | Symptomatic cardiotoxicity with high-dose 5-fluorouracil infusion: a prospective study显示文摘 | Akhtar S S Salim K P Bano Z A | 1993 | Ontology1993，50，6： | 1 |
| 16 | Comparative study between eystoscopy, urinary cytology, NMP- 22 and a new method, bladder chck, in the follow - up of superfieial bladder cell carcinoma 显示文摘 | Aguilera Tubet C Gutierrez Banos JL Antolln Juarez F | 2005 | Aetas Urol Esp2005，29，3： | 1 |
| 17 | Nepehinol-a new triterpene from Nepeta hindostana显示文摘 | Ahmad V U Bano S Mohammad F V | 1985 | Planta Med1985，，6： | 1 |
| 18 | Imaging of pancreatic serous cystadenocarcinoma 显示文摘 | Bano S Upreti L Puri SK | 2011 | Jpn J Radiol2011，29，10： | 1 |
| 19 | Prediction of bending load capacity of timber beams using a finite element method simulation of knots and grain deviation显示文摘 | Bano V Arriaga F Soilán A | 2011 | Biosystems Engineering2011，109，： | 1 |
| 20 | Current management of bloodstream infections显示文摘 | Rodriguez -Bano J de Cueto M Retamar P | 2010 | Expert Rev Anti Infection Ther2010，8，7： | 1 |
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