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| 1 | Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn's disease显示文摘AIM To determine levels of cytokines incolonic mucosa of asymptomatic first degreerelatives of Crohn’s disease patients.METHODS Cytokines(Interleukin(IL)1-Beta,IL-2,IL-5 and IL-8)were measured using ELISAin biopsy samples of normal looking colonicmucosa of first degree relatives of Crohn’sdisease patients(n = 9)and from normalcontrols(n = 10)with no family history ofCrohn’s disease.RESULTS Asymptomatic first degree relativesof patients with Crohn’s disease had significantlyhigher levels of basal intestinal mucosalcytokines(IL-2,IL-5 and IL-8)than normalcontrols.Whether these increased cytokinelevels serve as phenotypic markers for a geneticpredisposition to developing Crohns diseaselater on,or whether they indicate early(pre-clinical)damage has yet to be further defined.CONCLUSION Asymptomatic first degreerelatives of Crohn’s disease patients have higherlevels of cytokines in their normal-lookingintestinal mucosa compared to normal controls,This supports the hypothesis that increasedcytokines may be a cause or an early event inthe inflammatory cascade of Crohns disease andare not merely a result of the inflammatoryprocess. | Indaram AVK Nandi S Weissman S Lam S Bailey B Blumstein M Greenberg R Bank S | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 2 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 3 | 钒微合金钢的热塑性显示文摘低碳低氮微合金钢通常表现出抗横向开裂性能,而碳含量较高的微合金钢则不然。讨论了碳含量质量分数为0.05%~0.6%的含钒微合金钢的热塑性研究和工业经验。在不同碳含量的情况下,只要[V][N]乘积不超过1×10-3,添加的钒就能降低钢对横向开裂的敏感性。铌和钒的结合增加了800~900℃临界矫直温度范围内的热塑性,这一改善得益于钒和铌复合加入减缓了动态析出过程。在含钛钢中,最初在高温下生成的Ti N具有促进Ti Nb(C,N)沉淀粗化和降低对塑性不利的细小Nb V(C,N)沉淀体积分数的额外作用。还介绍了TWIP钢热塑性的最新结果以及含钒微合金钢连铸的工业经验。 | Banks K M Tuling A Mintz B | 2015 | 钢铁钒钛2015，36，5： | 2 |
| 4 | Firstsemester grades,thought modes,and undergraduate persistence显示文摘 | BIDDL B J &SHAVINGS R L | 1994 | Contemporary Educatonal Psychology1994，19，： | 1 |
| 5 | The effect of fenoxycarb on alate of the red imported fire ant显示文摘 | Glancey B M Banks W A Obin M S | 1989 | J Entomol Sci1989，24，： | 1 |
| 6 | Effects of extraction conditions and alkali type on yield and composition of wheat straw hemicellulose显示文摘 | LAWTHER J M SUN R C BANKS W B | 1996 | J Appl Polym Sci1996，60，11： | 1 |
| 7 | Re-duced greasiness of ‘ Granny Smith ’ apples washed in Tween 20 so-lution显示文摘 | DADZIE B K BANKS N H HEWETT E W CLELAND D J | 1995 | New Zealand Journal of Crop and Horticultural Science1995，23，2： | 1 |
| 8 | Extraction fraction and characterization of structural polysaccharides from wheat straw显示文摘 | MARK L J SUN Runcang BANKS W B | 1995 | Journal of Agricultural and Food Chemistry1995，43，3： | 1 |
| 9 | A note on the zeros of solutions of w' + P(z)ca = 0 where P is a polynomial 显示文摘 | Bank S B | 1987 | Appal Anal1987，25，： | 1 |
| 10 | On the frequency of zeros of solutions of second-order linear differential equations显示文摘 | LAINE I LANGLEY J K | 1986 | Results Math1986，，10： | 1 |
| 11 | A class of iterative methods for solving saddle point problems显示文摘 | Bank R E Welfert B D Yserentant H | 1990 | Numer Math1990，56，： | 1 |
| 12 | On the oscillation theory off' + Af = 0 where A is entire显示文摘 | Bank S B Laine I | 1982 | Trans Amer Math Soc1982，273，： | 1 |
| 13 | The Sodium Tungsten Bronzes显示文摘 | Brown B W Banks E | 1954 | J Am Chem Soc1954，76，4： | 1 |
| 14 | Pilot's Associate: A Coopertive,Knowledge-based System Application 显示文摘 | Shella B Bank Carl S Lizza | 1991 | IEEE Expert1991，6，3： | 1 |
| 15 | Fractional and structural characterization of wheat straw hemicelluloses显示文摘 | Sun R C Lawther J M Banks W B | 1996 | Carbohydrate Polymers1996，29，： | 1 |
| 16 | Fractional and structural characterization of wheat straw hemicelluloses显示文摘 | SUN R C LAWTHER J M BANKS W B | 1996 | Carbohydrate Polymers1996，29，： | 1 |
| 17 | 显示文摘 | Quinney R F Banks W B Lawther J M J | 1995 | J Wood Chem Tech1995，15，4： | 1 |
| 18 | Pilot's associate:A coopertive,knowledgebased system application显示文摘 | Bank S B Lizza C S | 1991 | IEEE Expert1991，6，3： | 1 |
| 19 | Ultrafiltrationversus usual care for hospitalizedpatients with heart failure: The Relief forAcutely Fluid overloaded Patients with Decompensated Congestive Heart Failure (RAPID--CHF) trial 显示文摘 | Bart B A Boyle A Bank A J | 2005 | Jam Coll Cardiol2005，46，： | 1 |
| 20 | 显示文摘 | Perry M D Stuart B C Banks P S | 1999 | J Appl Phys1999，85，： | 1 |
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